Angiotensin II Receptor 2 (AGTR2)
AT2R; AT2-R; ATGR2; AT2; MRX88
Angiotensin II is a potent pressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors termed AT1 and AT2. AGTR2 belongs to a family 1 of G protein-coupled receptors. It is an integral membrane protein. It plays a role in the central nervous system and cardiovascular functions that are mediated by the renin-angiotensin system. This receptor mediates programmed cell death (apoptosis). In adults, it is highly expressed in myometrium with lower levels in adrenal gland and fallopian tube. It is highly expressed in fetal kidney and intestine. The human AGTR2 gene is composed of three exons and spans at least 5 kb.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV839Hu01 | Recombinant Angiotensin II Receptor 2 (AGTR2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV839Hu01 | Monoclonal Antibody to Angiotensin II Receptor 2 (AGTR2) | WB; IHC; ICC; IP. |
| PAV839Hu01 | Polyclonal Antibody to Angiotensin II Receptor 2 (AGTR2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV839Hu01 | CLIA Kit for Angiotensin II Receptor 2 (AGTR2) | CLIA assay for Antigen Detection |
| ELV839Hu01 | ELISA Kit for Angiotensin II Receptor 2 (AGTR2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV839Mu01 | Recombinant Angiotensin II Receptor 2 (AGTR2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV839Mu01 | Monoclonal Antibody to Angiotensin II Receptor 2 (AGTR2) | WB; IHC; ICC; IP. |
| PAV839Mu01 | Polyclonal Antibody to Angiotensin II Receptor 2 (AGTR2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV839Mu01 | CLIA Kit for Angiotensin II Receptor 2 (AGTR2) | CLIA assay for Antigen Detection |
| ELV839Mu01 | ELISA Kit for Angiotensin II Receptor 2 (AGTR2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV839Ra01 | Recombinant Angiotensin II Receptor 2 (AGTR2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV839Ra01 | Monoclonal Antibody to Angiotensin II Receptor 2 (AGTR2) | WB; IHC; ICC; IP. |
| PAV839Ra01 | Polyclonal Antibody to Angiotensin II Receptor 2 (AGTR2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV839Ra01 | CLIA Kit for Angiotensin II Receptor 2 (AGTR2) | CLIA assay for Antigen Detection |
| ELV839Ra01 | ELISA Kit for Angiotensin II Receptor 2 (AGTR2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV839Ca01 | Recombinant Angiotensin II Receptor 2 (AGTR2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV839Ca01 | Monoclonal Antibody to Angiotensin II Receptor 2 (AGTR2) | WB; IHC; ICC; IP. |
| PAV839Ca01 | Polyclonal Antibody to Angiotensin II Receptor 2 (AGTR2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV839Ca01 | CLIA Kit for Angiotensin II Receptor 2 (AGTR2) | CLIA assay for Antigen Detection |
| ELV839Ca01 | ELISA Kit for Angiotensin II Receptor 2 (AGTR2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV839Po01 | Recombinant Angiotensin II Receptor 2 (AGTR2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV839Po01 | Monoclonal Antibody to Angiotensin II Receptor 2 (AGTR2) | WB; IHC; ICC; IP. |
| PAV839Po01 | Polyclonal Antibody to Angiotensin II Receptor 2 (AGTR2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV839Po01 | CLIA Kit for Angiotensin II Receptor 2 (AGTR2) | CLIA assay for Antigen Detection |
| ELV839Po01 | ELISA Kit for Angiotensin II Receptor 2 (AGTR2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV839Bo01 | Recombinant Angiotensin II Receptor 2 (AGTR2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV839Bo01 | Monoclonal Antibody to Angiotensin II Receptor 2 (AGTR2) | WB; IHC; ICC; IP. |
| PAV839Bo01 | Polyclonal Antibody to Angiotensin II Receptor 2 (AGTR2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV839Bo01 | CLIA Kit for Angiotensin II Receptor 2 (AGTR2) | CLIA assay for Antigen Detection |
| ELV839Bo01 | ELISA Kit for Angiotensin II Receptor 2 (AGTR2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV839Rb01 | Recombinant Angiotensin II Receptor 2 (AGTR2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV839Rb01 | Monoclonal Antibody to Angiotensin II Receptor 2 (AGTR2) | WB; IHC; ICC; IP. |
| PAV839Rb01 | Polyclonal Antibody to Angiotensin II Receptor 2 (AGTR2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV839Rb01 | CLIA Kit for Angiotensin II Receptor 2 (AGTR2) | CLIA assay for Antigen Detection |
| ELV839Rb01 | ELISA Kit for Angiotensin II Receptor 2 (AGTR2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV839Mo01 | Recombinant Angiotensin II Receptor 2 (AGTR2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV839Mo01 | Monoclonal Antibody to Angiotensin II Receptor 2 (AGTR2) | WB; IHC; ICC; IP. |
| PAV839Mo01 | Polyclonal Antibody to Angiotensin II Receptor 2 (AGTR2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV839Mo01 | CLIA Kit for Angiotensin II Receptor 2 (AGTR2) | CLIA assay for Antigen Detection |
| ELV839Mo01 | ELISA Kit for Angiotensin II Receptor 2 (AGTR2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"The sequence and genomic organization of the human type 2 angiotensin II receptor."
Biochem. Biophys. Res. Commun. 209:554-562(1995) [PubMed] [Europe PMC] [Abstract]
"Assignment of the human angiotensin II type 2 receptor gene (AGTR2) to chromosome Xq22-q23 by fluorescence in situ hybridization."
Genomics 25:601-603(1995) [PubMed] [Europe PMC] [Abstract]
"Human type 2 angiotensin II receptor gene: cloned, mapped to the X chromosome, and its mRNA is expressed in the human lung."
Biochem. Biophys. Res. Commun. 203:1842-1850(1994) [PubMed] [Europe PMC] [Abstract]
"Molecular cloning and expression of the gene encoding human angiotensin II type 2 receptor."
Biochem. Biophys. Res. Commun. 200:1449-1454(1994) [PubMed] [Europe PMC] [Abstract]
"Molecular cloning of the human angiotensin II type 2 receptor cDNA."
Biochem. Biophys. Res. Commun. 205:645-651(1994) [PubMed] [Europe PMC] [Abstract]
"Molecular characterization and chromosome localization of a human angiotensin II AT2 receptor gene highly expressed in fetal tissues."
Recept. Channels 2:271-280(1994) [PubMed] [Europe PMC] [Abstract]
"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
"The DNA sequence of the human X chromosome."
Nature 434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"AGTR2 mutations in X-linked mental retardation."
Science 296:2401-2403(2002) [PubMed] [Europe PMC] [Abstract]
"Trans-inactivation of receptor tyrosine kinases by novel angiotensin II AT2 receptor-interacting protein, ATIP."
J. Biol. Chem. 279:28989-28997(2004) [PubMed] [Europe PMC] [Abstract]
"XLID-causing mutations and associated genes challenged in light of data from large-scale human exome sequencing."
Am. J. Hum. Genet. 93:368-383(2013) [PubMed] [Europe PMC] [Abstract]