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Discoidin Domain Receptor Family, Member 1 (DDR1)

CD167a; CAK; DDR; EDDR1; MCK10; NEP; NTRK4; PTK3; PTK3A; RTK6; TRKE; Cell adhesion kinase; Epithelial discoidin domain receptor 1; Mammary carcinoma kinase 10

DDR1 is a RTK that is widely expressed in normal and transformed epithelial cells and is activated by various types of collagen. This protein belongs to a subfamily of tyrosine kinase receptors with a homology region to the Dictyostelium discoideum protein discoidin I in their extracellular domain. Its autophosphorylation is achieved by all collagens so far tested (type I to type VI). In situ studies and Northern-blot analysis showed that expression of this encoded protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, this protein is significantly over-expressed in several human tumors from breast, ovarian, esophageal, and pediatric brain. This gene is located on chromosome 6p21.3 in proximity to several HLA class I genes.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV835Hu01 Recombinant Discoidin Domain Receptor Family, Member 1 (DDR1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV835Hu01 Monoclonal Antibody to Discoidin Domain Receptor Family, Member 1 (DDR1) WB; IHC; ICC; IP.
PAV835Hu01 Polyclonal Antibody to Discoidin Domain Receptor Family, Member 1 (DDR1) WB; IHC; ICC; IF.
Assay Kits CLV835Hu01 CLIA Kit for Discoidin Domain Receptor Family, Member 1 (DDR1) CLIA assay for Antigen Detection
ELV835Hu01 ELISA Kit for Discoidin Domain Receptor Family, Member 1 (DDR1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV835Mu01 Recombinant Discoidin Domain Receptor Family, Member 1 (DDR1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV835Mu01 Monoclonal Antibody to Discoidin Domain Receptor Family, Member 1 (DDR1) WB; IHC; ICC; IP.
PAV835Mu01 Polyclonal Antibody to Discoidin Domain Receptor Family, Member 1 (DDR1) WB; IHC; ICC; IF.
Assay Kits CLV835Mu01 CLIA Kit for Discoidin Domain Receptor Family, Member 1 (DDR1) CLIA assay for Antigen Detection
ELV835Mu01 ELISA Kit for Discoidin Domain Receptor Family, Member 1 (DDR1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV835Ra01 Recombinant Discoidin Domain Receptor Family, Member 1 (DDR1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV835Ra01 Monoclonal Antibody to Discoidin Domain Receptor Family, Member 1 (DDR1) WB; IHC; ICC; IP.
PAV835Ra01 Polyclonal Antibody to Discoidin Domain Receptor Family, Member 1 (DDR1) WB; IHC; ICC; IF.
Assay Kits CLV835Ra01 CLIA Kit for Discoidin Domain Receptor Family, Member 1 (DDR1) CLIA assay for Antigen Detection
ELV835Ra01 ELISA Kit for Discoidin Domain Receptor Family, Member 1 (DDR1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV835Ca01 Recombinant Discoidin Domain Receptor Family, Member 1 (DDR1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV835Ca01 Monoclonal Antibody to Discoidin Domain Receptor Family, Member 1 (DDR1) WB; IHC; ICC; IP.
PAV835Ca01 Polyclonal Antibody to Discoidin Domain Receptor Family, Member 1 (DDR1) WB; IHC; ICC; IF.
Assay Kits CLV835Ca01 CLIA Kit for Discoidin Domain Receptor Family, Member 1 (DDR1) CLIA assay for Antigen Detection
ELV835Ca01 ELISA Kit for Discoidin Domain Receptor Family, Member 1 (DDR1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV835Po01 Recombinant Discoidin Domain Receptor Family, Member 1 (DDR1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV835Po01 Monoclonal Antibody to Discoidin Domain Receptor Family, Member 1 (DDR1) WB; IHC; ICC; IP.
PAV835Po01 Polyclonal Antibody to Discoidin Domain Receptor Family, Member 1 (DDR1) WB; IHC; ICC; IF.
Assay Kits CLV835Po01 CLIA Kit for Discoidin Domain Receptor Family, Member 1 (DDR1) CLIA assay for Antigen Detection
ELV835Po01 ELISA Kit for Discoidin Domain Receptor Family, Member 1 (DDR1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV835Bo01 Recombinant Discoidin Domain Receptor Family, Member 1 (DDR1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV835Bo01 Monoclonal Antibody to Discoidin Domain Receptor Family, Member 1 (DDR1) WB; IHC; ICC; IP.
PAV835Bo01 Polyclonal Antibody to Discoidin Domain Receptor Family, Member 1 (DDR1) WB; IHC; ICC; IF.
Assay Kits CLV835Bo01 CLIA Kit for Discoidin Domain Receptor Family, Member 1 (DDR1) CLIA assay for Antigen Detection
ELV835Bo01 ELISA Kit for Discoidin Domain Receptor Family, Member 1 (DDR1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV835Rb01 Recombinant Discoidin Domain Receptor Family, Member 1 (DDR1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV835Rb01 Monoclonal Antibody to Discoidin Domain Receptor Family, Member 1 (DDR1) WB; IHC; ICC; IP.
PAV835Rb01 Polyclonal Antibody to Discoidin Domain Receptor Family, Member 1 (DDR1) WB; IHC; ICC; IF.
Assay Kits CLV835Rb01 CLIA Kit for Discoidin Domain Receptor Family, Member 1 (DDR1) CLIA assay for Antigen Detection
ELV835Rb01 ELISA Kit for Discoidin Domain Receptor Family, Member 1 (DDR1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV835Mo01 Recombinant Discoidin Domain Receptor Family, Member 1 (DDR1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV835Mo01 Monoclonal Antibody to Discoidin Domain Receptor Family, Member 1 (DDR1) WB; IHC; ICC; IP.
PAV835Mo01 Polyclonal Antibody to Discoidin Domain Receptor Family, Member 1 (DDR1) WB; IHC; ICC; IF.
Assay Kits CLV835Mo01 CLIA Kit for Discoidin Domain Receptor Family, Member 1 (DDR1) CLIA assay for Antigen Detection
ELV835Mo01 ELISA Kit for Discoidin Domain Receptor Family, Member 1 (DDR1) Enzyme-linked immunosorbent assay for Antigen Detection

Reference

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"Structural mechanisms determining inhibition of the collagen receptor DDR1 by selective and multi-targeted type II kinase inhibitors."
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