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Albumin (ALB)

Serum albumin

  • Albumin is a soluble, monomeric protein which comprises about one-half of the blood serum protein. Albumin functions primarily as a carrier protein for steroids, fatty acids, and thyroid hormones and plays a role in stabilizing extracellular fluid volume. Mutations in the ALB gene on chromosome 4 result in various anomalous proteins.Albumin is a globular unglycosylated serum protein of molecular weight 65,000. The albumin variant first described by Fraser et al. in a Welsh family was characterized as a dimer by Jamieson and Ganguly. The amino acid sequence has been determined in fragments of serum albumin of man. By 1980, at least 2 dozen electrophoretic variants of serum albumin had been reported but only 2 of them had been characterized with respect to their primary structure: albumin A and albumin B.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV784Hu01 Recombinant Albumin (ALB) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV784Hu01 Monoclonal Antibody to Albumin (ALB) WB; IHC; ICC; IP.
PAV784Hu01 Polyclonal Antibody to Albumin (ALB) WB; IHC; ICC; IF.
Assay Kits CLV784Hu01 CLIA Kit for Albumin (ALB) CLIA assay for Antigen Detection
ELV784Hu01 ELISA Kit for Albumin (ALB) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV784Mu01 Recombinant Albumin (ALB) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV784Mu01 Monoclonal Antibody to Albumin (ALB) WB; IHC; ICC; IP.
PAV784Mu01 Polyclonal Antibody to Albumin (ALB) WB; IHC; ICC; IF.
Assay Kits CLV784Mu01 CLIA Kit for Albumin (ALB) CLIA assay for Antigen Detection
ELV784Mu01 ELISA Kit for Albumin (ALB) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV784Ra01 Recombinant Albumin (ALB) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV784Ra01 Monoclonal Antibody to Albumin (ALB) WB; IHC; ICC; IP.
PAV784Ra01 Polyclonal Antibody to Albumin (ALB) WB; IHC; ICC; IF.
Assay Kits CLV784Ra01 CLIA Kit for Albumin (ALB) CLIA assay for Antigen Detection
ELV784Ra01 ELISA Kit for Albumin (ALB) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV784Ca01 Recombinant Albumin (ALB) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV784Ca01 Monoclonal Antibody to Albumin (ALB) WB; IHC; ICC; IP.
PAV784Ca01 Polyclonal Antibody to Albumin (ALB) WB; IHC; ICC; IF.
Assay Kits CLV784Ca01 CLIA Kit for Albumin (ALB) CLIA assay for Antigen Detection
ELV784Ca01 ELISA Kit for Albumin (ALB) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV784Po01 Recombinant Albumin (ALB) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV784Po01 Monoclonal Antibody to Albumin (ALB) WB; IHC; ICC; IP.
PAV784Po01 Polyclonal Antibody to Albumin (ALB) WB; IHC; ICC; IF.
Assay Kits CLV784Po01 CLIA Kit for Albumin (ALB) CLIA assay for Antigen Detection
ELV784Po01 ELISA Kit for Albumin (ALB) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV784Bo01 Recombinant Albumin (ALB) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV784Bo01 Monoclonal Antibody to Albumin (ALB) WB; IHC; ICC; IP.
PAV784Bo01 Polyclonal Antibody to Albumin (ALB) WB; IHC; ICC; IF.
Assay Kits CLV784Bo01 CLIA Kit for Albumin (ALB) CLIA assay for Antigen Detection
ELV784Bo01 ELISA Kit for Albumin (ALB) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV784Rb01 Recombinant Albumin (ALB) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV784Rb01 Monoclonal Antibody to Albumin (ALB) WB; IHC; ICC; IP.
PAV784Rb01 Polyclonal Antibody to Albumin (ALB) WB; IHC; ICC; IF.
Assay Kits CLV784Rb01 CLIA Kit for Albumin (ALB) CLIA assay for Antigen Detection
ELV784Rb01 ELISA Kit for Albumin (ALB) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV784Mo01 Recombinant Albumin (ALB) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV784Mo01 Monoclonal Antibody to Albumin (ALB) WB; IHC; ICC; IP.
PAV784Mo01 Polyclonal Antibody to Albumin (ALB) WB; IHC; ICC; IF.
Assay Kits CLV784Mo01 CLIA Kit for Albumin (ALB) CLIA assay for Antigen Detection
ELV784Mo01 ELISA Kit for Albumin (ALB) Enzyme-linked immunosorbent assay for Antigen Detection

Reference

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, Submitted (DEC-2008) to UniProtKB

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"Albumin as a zinc carrier: properties of its high-affinity zinc-binding site."
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"Large-scale phosphoproteome analysis of human liver tissue by enrichment and fractionation of phosphopeptides with strong anion exchange chromatography."
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"Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
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"Initial characterization of the human central proteome."
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Erratum
Nature 364:362-362(1993)

"Crystal structure of human serum albumin complexed with fatty acid reveals an asymmetric distribution of binding sites."
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"Crystal structure of human serum albumin at 2.5-A resolution."
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"Amino acid substitutions in genetic variants of human serum albumin and in sequences inferred from molecular cloning."
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"Point substitutions in Japanese alloalbumins."
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"Albumin Redhill (-1 Arg, 320 Ala-->Thr): a glycoprotein variant of human serum albumin whose precursor has an aberrant signal peptidase cleavage site."
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"Mutations in genetic variants of human serum albumin found in Italy."
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"A donor splice mutation and a single-base deletion produce two carboxyl-terminal variants of human serum albumin."
Proc. Natl. Acad. Sci. U.S.A. 88:5959-5963(1991) [PubMed] [Europe PMC] [Abstract]

"Genetic variants of serum albumin in Americans and Japanese."
Proc. Natl. Acad. Sci. U.S.A. 88:9853-9857(1991) [PubMed] [Europe PMC] [Abstract]

"Structural characterization of a glycoprotein variant of human serum albumin: albumin Casebrook (494 Asp-->Asn)."
Biochim. Biophys. Acta 1097:49-54(1991) [PubMed] [Europe PMC] [Abstract]

"Two alloalbumins with identical electrophoretic mobility are produced by differently charged amino acid substitutions."
Biochim. Biophys. Acta 1119:232-238(1992) [PubMed] [Europe PMC] [Abstract]

"Alloalbuminemia in Sweden: structural study and phenotypic distribution of nine albumin variants."
Proc. Natl. Acad. Sci. U.S.A. 89:8225-8229(1992) [PubMed] [Europe PMC] [Abstract]

"The structural characterization and bilirubin-binding properties of albumin Herborn, a [Lys240-->Glu] albumin mutant."
Eur. J. Biochem. 214:437-444(1993) [PubMed] [Europe PMC] [Abstract]

"Albumin Hawkes Bay; a low level variant caused by loss of a sulphydryl group at position 177."
Biochim. Biophys. Acta 1182:46-50(1993) [PubMed] [Europe PMC] [Abstract]

"Protein and DNA sequence analysis of a 'private' genetic variant: albumin Ortonovo (Glu-505-->Lys)."
Biochim. Biophys. Acta 1225:27-32(1993) [PubMed] [Europe PMC] [Abstract]

"Genetic variants of human serum albumin in Italy: point mutants and a carboxyl-terminal variant."
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"An identical missense mutation in the albumin gene results in familial dysalbuminemic hyperthyroxinemia in 8 unrelated families."
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"Identification of a human serum albumin species associated with familial dysalbuminemic hyperthyroxinemia."
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"A novel missense mutation in codon 218 of the albumin gene in a distinct phenotype of familial dysalbuminemic hyperthyroxinemia in a Japanese kindred."
J. Clin. Endocrinol. Metab. 82:3246-3250(1997) [PubMed] [Europe PMC] [Abstract]

"Familial dysalbuminemic hypertriiodothyroninemia: a new, dominantly inherited albumin defect."
J. Clin. Endocrinol. Metab. 83:1448-1454(1998) [PubMed] [Europe PMC] [Abstract]

"Towards defining the urinary proteome using liquid chromatography-tandem mass spectrometry I. Profiling an unfractionated tryptic digest."
Proteomics 1:93-107(2001) [PubMed] [Europe PMC] [Abstract]

"A nucleotide insertion and frameshift cause albumin Kenitra, an extended and O-glycosylated mutant of human serum albumin with two additional disulfide bridges."
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