Vimentin (VIM)

SPN	V772
HGNC	12692
MGI	98932
PubMed	12483219
RGD	621646
UniProt	P08670
Wiki	Vimentin

Vimentin is a type III intermediate filament (IF) protein that is expressed in mesenchymal cells. IF proteins are found in all metazoan cells as well as bacteria. IF, along with tubulin-based microtubules and actin-based microfilaments, comprise the cytoskeleton. All IF proteins are expressed in a highly developmentally-regulated fashion; vimentin is the major cytoskeletal component of mesenchymal cells. Because of this, vimentin is often used as a marker of mesenchymally-derived cells or cells undergoing an epithelial-to-mesenchymal transition (EMT) during both normal development and metastatic progression. A vimentin monomer, like all other intermediate filaments, has a central α-helical domain, capped on each end by non-helical amino (head) and carboxyl (tail) domains.

Organism species: Homo sapiens (Human)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	V772Hu01	Recombinant Vimentin (VIM)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Vimentin (VIM)	Bioactivity
Antibodies	MV772Hu22	Monoclonal Antibody to Vimentin (VIM)	WB; IHC; ICC; IP.
	PV772Hu01	Polyclonal Antibody to Vimentin (VIM)	WB; IHC; ICC; IF.
	LV772Hu71	Biotin Linked-Polyclonal Antibody to Vimentin (VIM)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Vimentin (VIM)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Vimentin (VIM)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Vimentin (VIM)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Vimentin (VIM)	Flow Cytometry;ICC/IF
Assay Kits	KEV772Hu	ELISA Kit for Vimentin (VIM)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Vimentin (VIM)	CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	V772Mu01	Recombinant Vimentin (VIM)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Vimentin (VIM)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Vimentin (VIM)	WB; IHC; ICC; IP.
	PV772Mu01	Polyclonal Antibody to Vimentin (VIM)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Vimentin (VIM)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Vimentin (VIM)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Vimentin (VIM)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Vimentin (VIM)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Vimentin (VIM)	Flow Cytometry;ICC/IF
Assay Kits	KEV772Mu	ELISA Kit for Vimentin (VIM)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Vimentin (VIM)	CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Vimentin (VIM)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Vimentin (VIM)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Vimentin (VIM)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Vimentin (VIM)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Vimentin (VIM)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Vimentin (VIM)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Vimentin (VIM)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Vimentin (VIM)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Vimentin (VIM)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Vimentin (VIM)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Vimentin (VIM)	CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Vimentin (VIM)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Vimentin (VIM)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Vimentin (VIM)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Vimentin (VIM)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Vimentin (VIM)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Vimentin (VIM)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Vimentin (VIM)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Vimentin (VIM)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Vimentin (VIM)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Vimentin (VIM)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Vimentin (VIM)	CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Vimentin (VIM)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Vimentin (VIM)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Vimentin (VIM)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Vimentin (VIM)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Vimentin (VIM)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Vimentin (VIM)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Vimentin (VIM)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Vimentin (VIM)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Vimentin (VIM)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Vimentin (VIM)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Vimentin (VIM)	CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Vimentin (VIM)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Vimentin (VIM)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Vimentin (VIM)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Vimentin (VIM)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Vimentin (VIM)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Vimentin (VIM)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Vimentin (VIM)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Vimentin (VIM)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Vimentin (VIM)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Vimentin (VIM)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Vimentin (VIM)	CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Vimentin (VIM)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Vimentin (VIM)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Vimentin (VIM)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Vimentin (VIM)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Vimentin (VIM)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Vimentin (VIM)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Vimentin (VIM)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Vimentin (VIM)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Vimentin (VIM)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Vimentin (VIM)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Vimentin (VIM)	CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Vimentin (VIM)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Vimentin (VIM)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Vimentin (VIM)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Vimentin (VIM)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Vimentin (VIM)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Vimentin (VIM)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Vimentin (VIM)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Vimentin (VIM)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Vimentin (VIM)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Vimentin (VIM)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Vimentin (VIM)	CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Vimentin (VIM)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Vimentin (VIM)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Vimentin (VIM)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Vimentin (VIM)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Vimentin (VIM)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Vimentin (VIM)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Vimentin (VIM)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Vimentin (VIM)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Vimentin (VIM)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Vimentin (VIM)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Vimentin (VIM)	CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Vimentin (VIM)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Vimentin (VIM)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Vimentin (VIM)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Vimentin (VIM)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Vimentin (VIM)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Vimentin (VIM)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Vimentin (VIM)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Vimentin (VIM)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Vimentin (VIM)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Vimentin (VIM)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Vimentin (VIM)	CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Vimentin (VIM)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Vimentin (VIM)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Vimentin (VIM)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Vimentin (VIM)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Vimentin (VIM)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Vimentin (VIM)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Vimentin (VIM)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Vimentin (VIM)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Vimentin (VIM)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Vimentin (VIM)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Vimentin (VIM)	CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Vimentin (VIM)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Vimentin (VIM)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Vimentin (VIM)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Vimentin (VIM)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Vimentin (VIM)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Vimentin (VIM)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Vimentin (VIM)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Vimentin (VIM)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Vimentin (VIM)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Vimentin (VIM)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Vimentin (VIM)	CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Vimentin (VIM)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Vimentin (VIM)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Vimentin (VIM)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Vimentin (VIM)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Vimentin (VIM)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Vimentin (VIM)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Vimentin (VIM)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Vimentin (VIM)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Vimentin (VIM)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Vimentin (VIM)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Vimentin (VIM)	CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Vimentin (VIM)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Vimentin (VIM)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Vimentin (VIM)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Vimentin (VIM)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Vimentin (VIM)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Vimentin (VIM)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Vimentin (VIM)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Vimentin (VIM)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Vimentin (VIM)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Vimentin (VIM)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Vimentin (VIM)	CLIA assay for Antigen Detection

Reference

"Coding sequence and growth regulation of the human vimentin gene."
Mol. Cell. Biol. 6:3614-3620(1986) [PubMed] [Europe PMC] [Abstract]

"Nucleotide sequence of cDNA covering the complete coding part of the human vimentin gene."
Nucleic Acids Res. 18:6692-6692(1990) [PubMed] [Europe PMC] [Abstract]

"SEREX identification of new tumour-associated antigens in cutaneous T-cell lymphoma."
Br. J. Dermatol. 150:252-258(2004) [PubMed] [Europe PMC] [Abstract]

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

"The DNA sequence and comparative analysis of human chromosome 10."
Nature 429:375-381(2004) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Vimentin rather than keratin expression in some hormone-independent breast cancer cell lines and in oncogene-transformed mammary epithelial cells."
Cancer Res. 49:4258-4263(1989) [PubMed] [Europe PMC] [Abstract]

, Submitted (MAY-2006) to UniProtKB