Call Now

Motility Related Protein (MRP1)

CD9; TSPAN29; 5H9; BA2; BTCC-1; DRAP-27; GIG2; MIC3; P24; Tetraspanin 29; Cell growth-inhibiting gene 2 protein; Leukocyte antigen MIC3

Motility related protein is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility.

This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It can modulate cell adhesion and migration and also trigger platelet activation and aggregation. In addition, the protein appears to promote muscle cell fusion and support myotube maintenance.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV716Hu01 Recombinant Motility Related Protein (MRP1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV716Hu01 Monoclonal Antibody to Motility Related Protein (MRP1) WB; IHC; ICC; IP.
PAV716Hu01 Polyclonal Antibody to Motility Related Protein (MRP1) WB; IHC; ICC; IF.
Assay Kits CLV716Hu01 CLIA Kit for Motility Related Protein (MRP1) CLIA assay for Antigen Detection
ELV716Hu01 ELISA Kit for Motility Related Protein (MRP1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV716Mu01 Recombinant Motility Related Protein (MRP1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV716Mu01 Monoclonal Antibody to Motility Related Protein (MRP1) WB; IHC; ICC; IP.
PAV716Mu01 Polyclonal Antibody to Motility Related Protein (MRP1) WB; IHC; ICC; IF.
Assay Kits CLV716Mu01 CLIA Kit for Motility Related Protein (MRP1) CLIA assay for Antigen Detection
ELV716Mu01 ELISA Kit for Motility Related Protein (MRP1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV716Ra01 Recombinant Motility Related Protein (MRP1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV716Ra01 Monoclonal Antibody to Motility Related Protein (MRP1) WB; IHC; ICC; IP.
PAV716Ra01 Polyclonal Antibody to Motility Related Protein (MRP1) WB; IHC; ICC; IF.
Assay Kits CLV716Ra01 CLIA Kit for Motility Related Protein (MRP1) CLIA assay for Antigen Detection
ELV716Ra01 ELISA Kit for Motility Related Protein (MRP1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV716Ca01 Recombinant Motility Related Protein (MRP1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV716Ca01 Monoclonal Antibody to Motility Related Protein (MRP1) WB; IHC; ICC; IP.
PAV716Ca01 Polyclonal Antibody to Motility Related Protein (MRP1) WB; IHC; ICC; IF.
Assay Kits CLV716Ca01 CLIA Kit for Motility Related Protein (MRP1) CLIA assay for Antigen Detection
ELV716Ca01 ELISA Kit for Motility Related Protein (MRP1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV716Po01 Recombinant Motility Related Protein (MRP1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV716Po01 Monoclonal Antibody to Motility Related Protein (MRP1) WB; IHC; ICC; IP.
PAV716Po01 Polyclonal Antibody to Motility Related Protein (MRP1) WB; IHC; ICC; IF.
Assay Kits CLV716Po01 CLIA Kit for Motility Related Protein (MRP1) CLIA assay for Antigen Detection
ELV716Po01 ELISA Kit for Motility Related Protein (MRP1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV716Bo01 Recombinant Motility Related Protein (MRP1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV716Bo01 Monoclonal Antibody to Motility Related Protein (MRP1) WB; IHC; ICC; IP.
PAV716Bo01 Polyclonal Antibody to Motility Related Protein (MRP1) WB; IHC; ICC; IF.
Assay Kits CLV716Bo01 CLIA Kit for Motility Related Protein (MRP1) CLIA assay for Antigen Detection
ELV716Bo01 ELISA Kit for Motility Related Protein (MRP1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV716Rb01 Recombinant Motility Related Protein (MRP1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV716Rb01 Monoclonal Antibody to Motility Related Protein (MRP1) WB; IHC; ICC; IP.
PAV716Rb01 Polyclonal Antibody to Motility Related Protein (MRP1) WB; IHC; ICC; IF.
Assay Kits CLV716Rb01 CLIA Kit for Motility Related Protein (MRP1) CLIA assay for Antigen Detection
ELV716Rb01 ELISA Kit for Motility Related Protein (MRP1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV716Mo01 Recombinant Motility Related Protein (MRP1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV716Mo01 Monoclonal Antibody to Motility Related Protein (MRP1) WB; IHC; ICC; IP.
PAV716Mo01 Polyclonal Antibody to Motility Related Protein (MRP1) WB; IHC; ICC; IF.
Assay Kits CLV716Mo01 CLIA Kit for Motility Related Protein (MRP1) CLIA assay for Antigen Detection
ELV716Mo01 ELISA Kit for Motility Related Protein (MRP1) Enzyme-linked immunosorbent assay for Antigen Detection

Reference

"Molecular cloning of the CD9 antigen. A new family of cell surface proteins."
J. Biol. Chem. 266:117-122(1991) [PubMed] [Europe PMC] [Abstract]

"cDNA cloning and expression of platelet p24/CD9. Evidence for a new family of multiple membrane-spanning proteins."
J. Biol. Chem. 266:10638-10645(1991) [PubMed] [Europe PMC] [Abstract]

"Identification of the motility-related protein (MRP-1), recognized by monoclonal antibody M31-15, which inhibits cell motility."
J. Exp. Med. 174:1347-1354(1991) [PubMed] [Europe PMC] [Abstract]

"Organization of the human CD9 gene."
Genomics 16:132-138(1993) [PubMed] [Europe PMC] [Abstract]

"The tetraspanin CD9 is preferentially expressed on the human CD4(+)CD45RA+ naive T cell population and is involved in T cell activation."
Clin. Exp. Immunol. 137:101-108(2004) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Purification and partial characterization of CD9 antigen of human platelets."
FEBS Lett. 264:270-274(1990) [PubMed] [Europe PMC] [Abstract]

"Suppression of cell motility and metastasis by transfection with human motility-related protein (MRP-1/CD9) DNA."
J. Exp. Med. 177:1231-1237(1993) [PubMed] [Europe PMC] [Abstract]

"CD9-regulated adhesion. Anti-CD9 monoclonal antibody induce pre-B cell adhesion to bone marrow fibroblasts through de novo recognition of fibronectin."
J. Immunol. 152:2768-2777(1994) [PubMed] [Europe PMC] [Abstract]

"Structural requirements for the inhibitory action of the CD9 large extracellular domain in sperm/oocyte binding and fusion."
Biochem. Biophys. Res. Commun. 311:208-214(2003) [PubMed] [Europe PMC] [Abstract]

"Evidence for specific tetraspanin homodimers: inhibition of palmitoylation makes cysteine residues available for cross-linking."
Biochem. J. 377:407-417(2004) [PubMed] [Europe PMC] [Abstract]

"Differential stability of tetraspanin/tetraspanin interactions: role of palmitoylation."
FEBS Lett. 516:139-144(2002) [PubMed] [Europe PMC] [Abstract]

"The major CD9 and CD81 molecular partner. Identification and characterization of the complexes."
J. Biol. Chem. 276:14329-14337(2001) [PubMed] [Europe PMC] [Abstract]

"EWI-2 is a major CD9 and CD81 partner and member of a novel Ig protein subfamily."
J. Biol. Chem. 276:40545-40554(2001) [PubMed] [Europe PMC] [Abstract]

"Palmitoylation supports the association of tetraspanin CD63 with CD9 and integrin alphaIIbbeta3 in activated platelets."
Thromb. Res. 125:152-158(2010) [PubMed] [Europe PMC] [Abstract]

"Initial characterization of the human central proteome."
BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]