Cluster Of Differentiation 8a (CD8a)
p32; CD8-A; Leu2; MAL; T-cell surface glycoprotein CD8 alpha chain; T-lymphocyte differentiation antigen T8/Leu-2
The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain isoforms. Two alternative transcripts encoding distinct isoforms, one membrane associated and one secreted, have been identified.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | V714Hu01 | Recombinant Cluster Of Differentiation 8a (CD8a) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Cluster Of Differentiation 8a (CD8a) | Bioactivity | |
| Antibodies | MV714Hu22 | Monoclonal Antibody to Cluster Of Differentiation 8a (CD8a) | WB; IHC; ICC; IP. |
| PV714Hu01 | Polyclonal Antibody to Cluster Of Differentiation 8a (CD8a) | WB; IHC; ICC; IF. | |
| LV714Hu71 | Biotin Linked-Polyclonal Antibody to Cluster Of Differentiation 8a (CD8a) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Cluster Of Differentiation 8a (CD8a) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Cluster Of Differentiation 8a (CD8a) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Cluster Of Differentiation 8a (CD8a) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Cluster Of Differentiation 8a (CD8a) | Flow Cytometry;ICC/IF | |
| Assay Kits | KEV714Hu | ELISA Kit for Cluster Of Differentiation 8a (CD8a) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Cluster Of Differentiation 8a (CD8a) | CLIA assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | V714Mu01 | Recombinant Cluster Of Differentiation 8a (CD8a) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Cluster Of Differentiation 8a (CD8a) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Cluster Of Differentiation 8a (CD8a) | WB; IHC; ICC; IP. |
| PV714Mu01 | Polyclonal Antibody to Cluster Of Differentiation 8a (CD8a) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Cluster Of Differentiation 8a (CD8a) | ELISA(Det);IC; IH; IH(P); WB | |
| LV714Mu51 | APC Linked-Polyclonal Antibody to Cluster Of Differentiation 8a (CD8a) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Cluster Of Differentiation 8a (CD8a) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Cluster Of Differentiation 8a (CD8a) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Cluster Of Differentiation 8a (CD8a) | Flow Cytometry;ICC/IF | |
| Assay Kits | KEV714Mu | ELISA Kit for Cluster Of Differentiation 8a (CD8a) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Cluster Of Differentiation 8a (CD8a) | CLIA assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Cluster Of Differentiation 8a (CD8a) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Cluster Of Differentiation 8a (CD8a) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Cluster Of Differentiation 8a (CD8a) | WB; IHC; ICC; IP. |
| PV714Ra01 | Polyclonal Antibody to Cluster Of Differentiation 8a (CD8a) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Cluster Of Differentiation 8a (CD8a) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Cluster Of Differentiation 8a (CD8a) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Cluster Of Differentiation 8a (CD8a) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Cluster Of Differentiation 8a (CD8a) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Cluster Of Differentiation 8a (CD8a) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Cluster Of Differentiation 8a (CD8a) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Cluster Of Differentiation 8a (CD8a) | CLIA assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Cluster Of Differentiation 8a (CD8a) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Cluster Of Differentiation 8a (CD8a) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Cluster Of Differentiation 8a (CD8a) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Cluster Of Differentiation 8a (CD8a) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Cluster Of Differentiation 8a (CD8a) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Cluster Of Differentiation 8a (CD8a) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Cluster Of Differentiation 8a (CD8a) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Cluster Of Differentiation 8a (CD8a) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Cluster Of Differentiation 8a (CD8a) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Cluster Of Differentiation 8a (CD8a) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Cluster Of Differentiation 8a (CD8a) | CLIA assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Cluster Of Differentiation 8a (CD8a) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Cluster Of Differentiation 8a (CD8a) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Cluster Of Differentiation 8a (CD8a) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Cluster Of Differentiation 8a (CD8a) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Cluster Of Differentiation 8a (CD8a) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Cluster Of Differentiation 8a (CD8a) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Cluster Of Differentiation 8a (CD8a) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Cluster Of Differentiation 8a (CD8a) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Cluster Of Differentiation 8a (CD8a) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Cluster Of Differentiation 8a (CD8a) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Cluster Of Differentiation 8a (CD8a) | CLIA assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Cluster Of Differentiation 8a (CD8a) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Cluster Of Differentiation 8a (CD8a) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Cluster Of Differentiation 8a (CD8a) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Cluster Of Differentiation 8a (CD8a) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Cluster Of Differentiation 8a (CD8a) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Cluster Of Differentiation 8a (CD8a) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Cluster Of Differentiation 8a (CD8a) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Cluster Of Differentiation 8a (CD8a) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Cluster Of Differentiation 8a (CD8a) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Cluster Of Differentiation 8a (CD8a) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Cluster Of Differentiation 8a (CD8a) | CLIA assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Cluster Of Differentiation 8a (CD8a) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Cluster Of Differentiation 8a (CD8a) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Cluster Of Differentiation 8a (CD8a) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Cluster Of Differentiation 8a (CD8a) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Cluster Of Differentiation 8a (CD8a) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Cluster Of Differentiation 8a (CD8a) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Cluster Of Differentiation 8a (CD8a) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Cluster Of Differentiation 8a (CD8a) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Cluster Of Differentiation 8a (CD8a) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Cluster Of Differentiation 8a (CD8a) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Cluster Of Differentiation 8a (CD8a) | CLIA assay for Antigen Detection |
Organism species: Chicken (Gallus)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Cluster Of Differentiation 8a (CD8a) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Cluster Of Differentiation 8a (CD8a) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Cluster Of Differentiation 8a (CD8a) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Cluster Of Differentiation 8a (CD8a) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Cluster Of Differentiation 8a (CD8a) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Cluster Of Differentiation 8a (CD8a) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Cluster Of Differentiation 8a (CD8a) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Cluster Of Differentiation 8a (CD8a) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Cluster Of Differentiation 8a (CD8a) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Cluster Of Differentiation 8a (CD8a) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Cluster Of Differentiation 8a (CD8a) | CLIA assay for Antigen Detection |
Organism species: Ovis aries; Ovine (Sheep)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Cluster Of Differentiation 8a (CD8a) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Cluster Of Differentiation 8a (CD8a) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Cluster Of Differentiation 8a (CD8a) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Cluster Of Differentiation 8a (CD8a) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Cluster Of Differentiation 8a (CD8a) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Cluster Of Differentiation 8a (CD8a) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Cluster Of Differentiation 8a (CD8a) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Cluster Of Differentiation 8a (CD8a) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Cluster Of Differentiation 8a (CD8a) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Cluster Of Differentiation 8a (CD8a) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Cluster Of Differentiation 8a (CD8a) | CLIA assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Cluster Of Differentiation 8a (CD8a) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Cluster Of Differentiation 8a (CD8a) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Cluster Of Differentiation 8a (CD8a) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Cluster Of Differentiation 8a (CD8a) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Cluster Of Differentiation 8a (CD8a) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Cluster Of Differentiation 8a (CD8a) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Cluster Of Differentiation 8a (CD8a) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Cluster Of Differentiation 8a (CD8a) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Cluster Of Differentiation 8a (CD8a) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Cluster Of Differentiation 8a (CD8a) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Cluster Of Differentiation 8a (CD8a) | CLIA assay for Antigen Detection |
Organism species: Cavia (Guinea pig )
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Cluster Of Differentiation 8a (CD8a) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Cluster Of Differentiation 8a (CD8a) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Cluster Of Differentiation 8a (CD8a) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Cluster Of Differentiation 8a (CD8a) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Cluster Of Differentiation 8a (CD8a) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Cluster Of Differentiation 8a (CD8a) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Cluster Of Differentiation 8a (CD8a) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Cluster Of Differentiation 8a (CD8a) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Cluster Of Differentiation 8a (CD8a) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Cluster Of Differentiation 8a (CD8a) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Cluster Of Differentiation 8a (CD8a) | CLIA assay for Antigen Detection |
Organism species: Equus caballus; Equine (Horse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Cluster Of Differentiation 8a (CD8a) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Cluster Of Differentiation 8a (CD8a) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Cluster Of Differentiation 8a (CD8a) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Cluster Of Differentiation 8a (CD8a) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Cluster Of Differentiation 8a (CD8a) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Cluster Of Differentiation 8a (CD8a) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Cluster Of Differentiation 8a (CD8a) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Cluster Of Differentiation 8a (CD8a) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Cluster Of Differentiation 8a (CD8a) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Cluster Of Differentiation 8a (CD8a) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Cluster Of Differentiation 8a (CD8a) | CLIA assay for Antigen Detection |
Organism species: Capra hircus; Caprine (Goat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Cluster Of Differentiation 8a (CD8a) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Cluster Of Differentiation 8a (CD8a) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Cluster Of Differentiation 8a (CD8a) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Cluster Of Differentiation 8a (CD8a) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Cluster Of Differentiation 8a (CD8a) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Cluster Of Differentiation 8a (CD8a) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Cluster Of Differentiation 8a (CD8a) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Cluster Of Differentiation 8a (CD8a) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Cluster Of Differentiation 8a (CD8a) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Cluster Of Differentiation 8a (CD8a) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Cluster Of Differentiation 8a (CD8a) | CLIA assay for Antigen Detection |
Organism species: Pan-species (General)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Cluster Of Differentiation 8a (CD8a) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Cluster Of Differentiation 8a (CD8a) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Cluster Of Differentiation 8a (CD8a) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Cluster Of Differentiation 8a (CD8a) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Cluster Of Differentiation 8a (CD8a) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Cluster Of Differentiation 8a (CD8a) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Cluster Of Differentiation 8a (CD8a) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Cluster Of Differentiation 8a (CD8a) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Cluster Of Differentiation 8a (CD8a) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Cluster Of Differentiation 8a (CD8a) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Cluster Of Differentiation 8a (CD8a) | CLIA assay for Antigen Detection |
Reference
"The isolation and sequence of the gene encoding T8: a molecule defining functional classes of T lymphocytes."
Cell 40:237-246(1985) [PubMed] [Europe PMC] [Abstract]
"Structure of Leu-2/T8 as deduced from the sequence of a cDNA clone."
Behring Inst. Mitt. 77:48-55(1985) [PubMed] [Europe PMC] [Abstract]
"The T cell differentiation antigen Leu-2/T8 is homologous to immunoglobulin and T cell receptor variable regions."
Cell 40:591-597(1985) [PubMed] [Europe PMC] [Abstract]
"Structure and expression of the gene encoding CD8 alpha chain (Leu-2/T8)."
Immunogenetics 30:393-397(1989) [PubMed] [Europe PMC] [Abstract]
"Alternatively spliced mRNA encodes a secreted form of human CD8 alpha. Characterization of the human CD8 alpha gene."
J. Immunol. 142:3312-3319(1989) [PubMed] [Europe PMC] [Abstract]
"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
"Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
"A secreted form of the human lymphocyte cell surface molecule CD8 arises from alternative splicing."
Proc. Natl. Acad. Sci. U.S.A. 86:998-1002(1989) [PubMed] [Europe PMC] [Abstract]
"The T8 antigen is a multimeric complex of two distinct subunits on human thymocytes but consists of homomultimeric forms on peripheral blood T lymphocytes."
J. Biol. Chem. 258:14675-14681(1983) [PubMed] [Europe PMC] [Abstract]
"Crystal structure of a soluble form of the human T cell coreceptor CD8 at 2.6-A resolution."
Cell 68:1145-1162(1992) [PubMed] [Europe PMC] [Abstract]
"Crystal structure of the complex between human CD8alpha(alpha) and HLA-A2."
Nature 387:630-634(1997) [PubMed] [Europe PMC] [Abstract]
"A zinc clasp structure tethers Lck to T cell coreceptors CD4 and CD8."
Science 301:1725-1728(2003) [PubMed] [Europe PMC] [Abstract]
"Familial CD8 deficiency due to a mutation in the CD8 alpha gene."
J. Clin. Invest. 108:117-123(2001) [PubMed] [Europe PMC] [Abstract]