Deoxyribonuclease I (DNASE1)
DNaseI; DNL1; DRNI; DNase-I; Dornase alfa
DNase I is a nuclease that cleaves DNA preferentially at phosphodiester linkages adjacent to a pyrimidine nucleotide, yielding 5'-phosphate terminated polynucleotides with a free hydroxyl group on position 3', on average producing tetranucleotides. It acts on single-stranded DNA, double-stranded DNA, and chromatin. It has been suggested to be one of the deoxyribonucleases responsible for DNA fragmentation during apoptosis.DNase I binds to the cytoskeletal protein actin. It binds actin monomers with very high (sub-nanomolar) affinity and actin polymers with lower affinity. The function of this interaction is unclear. However since actin-bound DNase I is enzymatically inactive, the DNase-actin complex might be a storage form of DNase I that prevents damage of the genetic information.
Organism species: Homo sapiens (Human)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | V686Hu01 | Recombinant Deoxyribonuclease I (DNASE1) | Positive Control; Immunogen; SDS-PAGE; WB. |
NONE | Native Deoxyribonuclease I (DNASE1) | Bioactivity | |
Antibodies | MV686Hu21 | Monoclonal Antibody to Deoxyribonuclease I (DNASE1) | WB; IHC; ICC; IP. |
PV686Hu01 | Polyclonal Antibody to Deoxyribonuclease I (DNASE1) | WB; IHC; ICC; IF. | |
LV686Hu71 | Biotin Linked-Polyclonal Antibody to Deoxyribonuclease I (DNASE1) | ELISA(Det);IC; IH; IH(P); WB | |
NONE | APC Linked-Polyclonal Antibody to Deoxyribonuclease I (DNASE1) | IHC, WB | |
NONE | HRP Linked-Polyclonal Antibody to Deoxyribonuclease I (DNASE1) | Simple Western; WB | |
NONE | PE Linked-Polyclonal Antibody to Deoxyribonuclease I (DNASE1) | Flow Cytometry | |
LV686Hu82 | FITC Linked-Polyclonal Antibody to Deoxyribonuclease I (DNASE1) | Flow Cytometry;ICC/IF | |
Assay Kits | KEV686Hu | ELISA Kit for Deoxyribonuclease I (DNASE1) | Enzyme-linked immunosorbent assay for Antigen Detection |
NONE | CLIA kit for Deoxyribonuclease I (DNASE1) | CLIA assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | V686Mu01 | Recombinant Deoxyribonuclease I (DNASE1) | Positive Control; Immunogen; SDS-PAGE; WB. |
NONE | Native Deoxyribonuclease I (DNASE1) | Bioactivity | |
Antibodies | NONE | Monoclonal Antibody to Deoxyribonuclease I (DNASE1) | WB; IHC; ICC; IP. |
PV686Mu01 | Polyclonal Antibody to Deoxyribonuclease I (DNASE1) | WB; IHC; ICC; IF. | |
NONE | Biotin Linked-Polyclonal Antibody to Deoxyribonuclease I (DNASE1) | ELISA(Det);IC; IH; IH(P); WB | |
NONE | APC Linked-Polyclonal Antibody to Deoxyribonuclease I (DNASE1) | IHC, WB | |
NONE | HRP Linked-Polyclonal Antibody to Deoxyribonuclease I (DNASE1) | Simple Western; WB | |
NONE | PE Linked-Polyclonal Antibody to Deoxyribonuclease I (DNASE1) | Flow Cytometry | |
NONE | FITC Linked-Polyclonal Antibody to Deoxyribonuclease I (DNASE1) | Flow Cytometry;ICC/IF | |
Assay Kits | KEV686Mu | ELISA Kit for Deoxyribonuclease I (DNASE1) | Enzyme-linked immunosorbent assay for Antigen Detection |
NONE | CLIA kit for Deoxyribonuclease I (DNASE1) | CLIA assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | NONE | Recombinant Deoxyribonuclease I (DNASE1) | Positive Control; Immunogen; SDS-PAGE; WB. |
NONE | Native Deoxyribonuclease I (DNASE1) | Bioactivity | |
Antibodies | NONE | Monoclonal Antibody to Deoxyribonuclease I (DNASE1) | WB; IHC; ICC; IP. |
NONE | Polyclonal Antibody to Deoxyribonuclease I (DNASE1) | WB; IHC; ICC; IF. | |
NONE | Biotin Linked-Polyclonal Antibody to Deoxyribonuclease I (DNASE1) | ELISA(Det);IC; IH; IH(P); WB | |
NONE | APC Linked-Polyclonal Antibody to Deoxyribonuclease I (DNASE1) | IHC, WB | |
NONE | HRP Linked-Polyclonal Antibody to Deoxyribonuclease I (DNASE1) | Simple Western; WB | |
NONE | PE Linked-Polyclonal Antibody to Deoxyribonuclease I (DNASE1) | Flow Cytometry | |
NONE | FITC Linked-Polyclonal Antibody to Deoxyribonuclease I (DNASE1) | Flow Cytometry;ICC/IF | |
Assay Kits | NONE | ELISA Kit for Deoxyribonuclease I (DNASE1) | Enzyme-linked immunosorbent assay for Antigen Detection |
NONE | CLIA kit for Deoxyribonuclease I (DNASE1) | CLIA assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | NONE | Recombinant Deoxyribonuclease I (DNASE1) | Positive Control; Immunogen; SDS-PAGE; WB. |
NONE | Native Deoxyribonuclease I (DNASE1) | Bioactivity | |
Antibodies | NONE | Monoclonal Antibody to Deoxyribonuclease I (DNASE1) | WB; IHC; ICC; IP. |
NONE | Polyclonal Antibody to Deoxyribonuclease I (DNASE1) | WB; IHC; ICC; IF. | |
NONE | Biotin Linked-Polyclonal Antibody to Deoxyribonuclease I (DNASE1) | ELISA(Det);IC; IH; IH(P); WB | |
NONE | APC Linked-Polyclonal Antibody to Deoxyribonuclease I (DNASE1) | IHC, WB | |
NONE | HRP Linked-Polyclonal Antibody to Deoxyribonuclease I (DNASE1) | Simple Western; WB | |
NONE | PE Linked-Polyclonal Antibody to Deoxyribonuclease I (DNASE1) | Flow Cytometry | |
NONE | FITC Linked-Polyclonal Antibody to Deoxyribonuclease I (DNASE1) | Flow Cytometry;ICC/IF | |
Assay Kits | NONE | ELISA Kit for Deoxyribonuclease I (DNASE1) | Enzyme-linked immunosorbent assay for Antigen Detection |
NONE | CLIA kit for Deoxyribonuclease I (DNASE1) | CLIA assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | NONE | Recombinant Deoxyribonuclease I (DNASE1) | Positive Control; Immunogen; SDS-PAGE; WB. |
NONE | Native Deoxyribonuclease I (DNASE1) | Bioactivity | |
Antibodies | NONE | Monoclonal Antibody to Deoxyribonuclease I (DNASE1) | WB; IHC; ICC; IP. |
NONE | Polyclonal Antibody to Deoxyribonuclease I (DNASE1) | WB; IHC; ICC; IF. | |
NONE | Biotin Linked-Polyclonal Antibody to Deoxyribonuclease I (DNASE1) | ELISA(Det);IC; IH; IH(P); WB | |
NONE | APC Linked-Polyclonal Antibody to Deoxyribonuclease I (DNASE1) | IHC, WB | |
NONE | HRP Linked-Polyclonal Antibody to Deoxyribonuclease I (DNASE1) | Simple Western; WB | |
NONE | PE Linked-Polyclonal Antibody to Deoxyribonuclease I (DNASE1) | Flow Cytometry | |
NONE | FITC Linked-Polyclonal Antibody to Deoxyribonuclease I (DNASE1) | Flow Cytometry;ICC/IF | |
Assay Kits | NONE | ELISA Kit for Deoxyribonuclease I (DNASE1) | Enzyme-linked immunosorbent assay for Antigen Detection |
NONE | CLIA kit for Deoxyribonuclease I (DNASE1) | CLIA assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | V686Bo01 | Recombinant Deoxyribonuclease I (DNASE1) | Positive Control; Immunogen; SDS-PAGE; WB. |
NONE | Native Deoxyribonuclease I (DNASE1) | Bioactivity | |
Antibodies | MV686Bo21 | Monoclonal Antibody to Deoxyribonuclease I (DNASE1) | WB; IHC; ICC; IP. |
PV686Bo01 | Polyclonal Antibody to Deoxyribonuclease I (DNASE1) | WB; IHC; ICC; IF. | |
NONE | Biotin Linked-Polyclonal Antibody to Deoxyribonuclease I (DNASE1) | ELISA(Det);IC; IH; IH(P); WB | |
NONE | APC Linked-Polyclonal Antibody to Deoxyribonuclease I (DNASE1) | IHC, WB | |
NONE | HRP Linked-Polyclonal Antibody to Deoxyribonuclease I (DNASE1) | Simple Western; WB | |
NONE | PE Linked-Polyclonal Antibody to Deoxyribonuclease I (DNASE1) | Flow Cytometry | |
NONE | FITC Linked-Polyclonal Antibody to Deoxyribonuclease I (DNASE1) | Flow Cytometry;ICC/IF | |
Assay Kits | KEV686Bo | ELISA Kit for Deoxyribonuclease I (DNASE1) | Enzyme-linked immunosorbent assay for Antigen Detection |
NONE | CLIA kit for Deoxyribonuclease I (DNASE1) | CLIA assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | NONE | Recombinant Deoxyribonuclease I (DNASE1) | Positive Control; Immunogen; SDS-PAGE; WB. |
NONE | Native Deoxyribonuclease I (DNASE1) | Bioactivity | |
Antibodies | NONE | Monoclonal Antibody to Deoxyribonuclease I (DNASE1) | WB; IHC; ICC; IP. |
NONE | Polyclonal Antibody to Deoxyribonuclease I (DNASE1) | WB; IHC; ICC; IF. | |
NONE | Biotin Linked-Polyclonal Antibody to Deoxyribonuclease I (DNASE1) | ELISA(Det);IC; IH; IH(P); WB | |
NONE | APC Linked-Polyclonal Antibody to Deoxyribonuclease I (DNASE1) | IHC, WB | |
NONE | HRP Linked-Polyclonal Antibody to Deoxyribonuclease I (DNASE1) | Simple Western; WB | |
NONE | PE Linked-Polyclonal Antibody to Deoxyribonuclease I (DNASE1) | Flow Cytometry | |
NONE | FITC Linked-Polyclonal Antibody to Deoxyribonuclease I (DNASE1) | Flow Cytometry;ICC/IF | |
Assay Kits | NONE | ELISA Kit for Deoxyribonuclease I (DNASE1) | Enzyme-linked immunosorbent assay for Antigen Detection |
NONE | CLIA kit for Deoxyribonuclease I (DNASE1) | CLIA assay for Antigen Detection |
Organism species: Chicken (Gallus)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | NONE | Recombinant Deoxyribonuclease I (DNASE1) | Positive Control; Immunogen; SDS-PAGE; WB. |
NONE | Native Deoxyribonuclease I (DNASE1) | Bioactivity | |
Antibodies | NONE | Monoclonal Antibody to Deoxyribonuclease I (DNASE1) | WB; IHC; ICC; IP. |
NONE | Polyclonal Antibody to Deoxyribonuclease I (DNASE1) | WB; IHC; ICC; IF. | |
NONE | Biotin Linked-Polyclonal Antibody to Deoxyribonuclease I (DNASE1) | ELISA(Det);IC; IH; IH(P); WB | |
NONE | APC Linked-Polyclonal Antibody to Deoxyribonuclease I (DNASE1) | IHC, WB | |
NONE | HRP Linked-Polyclonal Antibody to Deoxyribonuclease I (DNASE1) | Simple Western; WB | |
NONE | PE Linked-Polyclonal Antibody to Deoxyribonuclease I (DNASE1) | Flow Cytometry | |
NONE | FITC Linked-Polyclonal Antibody to Deoxyribonuclease I (DNASE1) | Flow Cytometry;ICC/IF | |
Assay Kits | NONE | ELISA Kit for Deoxyribonuclease I (DNASE1) | Enzyme-linked immunosorbent assay for Antigen Detection |
NONE | CLIA kit for Deoxyribonuclease I (DNASE1) | CLIA assay for Antigen Detection |
Organism species: Ovis aries; Ovine (Sheep)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | NONE | Recombinant Deoxyribonuclease I (DNASE1) | Positive Control; Immunogen; SDS-PAGE; WB. |
NONE | Native Deoxyribonuclease I (DNASE1) | Bioactivity | |
Antibodies | NONE | Monoclonal Antibody to Deoxyribonuclease I (DNASE1) | WB; IHC; ICC; IP. |
NONE | Polyclonal Antibody to Deoxyribonuclease I (DNASE1) | WB; IHC; ICC; IF. | |
NONE | Biotin Linked-Polyclonal Antibody to Deoxyribonuclease I (DNASE1) | ELISA(Det);IC; IH; IH(P); WB | |
NONE | APC Linked-Polyclonal Antibody to Deoxyribonuclease I (DNASE1) | IHC, WB | |
NONE | HRP Linked-Polyclonal Antibody to Deoxyribonuclease I (DNASE1) | Simple Western; WB | |
NONE | PE Linked-Polyclonal Antibody to Deoxyribonuclease I (DNASE1) | Flow Cytometry | |
NONE | FITC Linked-Polyclonal Antibody to Deoxyribonuclease I (DNASE1) | Flow Cytometry;ICC/IF | |
Assay Kits | NONE | ELISA Kit for Deoxyribonuclease I (DNASE1) | Enzyme-linked immunosorbent assay for Antigen Detection |
NONE | CLIA kit for Deoxyribonuclease I (DNASE1) | CLIA assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | NONE | Recombinant Deoxyribonuclease I (DNASE1) | Positive Control; Immunogen; SDS-PAGE; WB. |
NONE | Native Deoxyribonuclease I (DNASE1) | Bioactivity | |
Antibodies | NONE | Monoclonal Antibody to Deoxyribonuclease I (DNASE1) | WB; IHC; ICC; IP. |
NONE | Polyclonal Antibody to Deoxyribonuclease I (DNASE1) | WB; IHC; ICC; IF. | |
NONE | Biotin Linked-Polyclonal Antibody to Deoxyribonuclease I (DNASE1) | ELISA(Det);IC; IH; IH(P); WB | |
NONE | APC Linked-Polyclonal Antibody to Deoxyribonuclease I (DNASE1) | IHC, WB | |
NONE | HRP Linked-Polyclonal Antibody to Deoxyribonuclease I (DNASE1) | Simple Western; WB | |
NONE | PE Linked-Polyclonal Antibody to Deoxyribonuclease I (DNASE1) | Flow Cytometry | |
NONE | FITC Linked-Polyclonal Antibody to Deoxyribonuclease I (DNASE1) | Flow Cytometry;ICC/IF | |
Assay Kits | NONE | ELISA Kit for Deoxyribonuclease I (DNASE1) | Enzyme-linked immunosorbent assay for Antigen Detection |
NONE | CLIA kit for Deoxyribonuclease I (DNASE1) | CLIA assay for Antigen Detection |
Organism species: Cavia (Guinea pig )
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | NONE | Recombinant Deoxyribonuclease I (DNASE1) | Positive Control; Immunogen; SDS-PAGE; WB. |
NONE | Native Deoxyribonuclease I (DNASE1) | Bioactivity | |
Antibodies | NONE | Monoclonal Antibody to Deoxyribonuclease I (DNASE1) | WB; IHC; ICC; IP. |
NONE | Polyclonal Antibody to Deoxyribonuclease I (DNASE1) | WB; IHC; ICC; IF. | |
NONE | Biotin Linked-Polyclonal Antibody to Deoxyribonuclease I (DNASE1) | ELISA(Det);IC; IH; IH(P); WB | |
NONE | APC Linked-Polyclonal Antibody to Deoxyribonuclease I (DNASE1) | IHC, WB | |
NONE | HRP Linked-Polyclonal Antibody to Deoxyribonuclease I (DNASE1) | Simple Western; WB | |
NONE | PE Linked-Polyclonal Antibody to Deoxyribonuclease I (DNASE1) | Flow Cytometry | |
NONE | FITC Linked-Polyclonal Antibody to Deoxyribonuclease I (DNASE1) | Flow Cytometry;ICC/IF | |
Assay Kits | NONE | ELISA Kit for Deoxyribonuclease I (DNASE1) | Enzyme-linked immunosorbent assay for Antigen Detection |
NONE | CLIA kit for Deoxyribonuclease I (DNASE1) | CLIA assay for Antigen Detection |
Organism species: Equus caballus; Equine (Horse)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | NONE | Recombinant Deoxyribonuclease I (DNASE1) | Positive Control; Immunogen; SDS-PAGE; WB. |
NONE | Native Deoxyribonuclease I (DNASE1) | Bioactivity | |
Antibodies | NONE | Monoclonal Antibody to Deoxyribonuclease I (DNASE1) | WB; IHC; ICC; IP. |
NONE | Polyclonal Antibody to Deoxyribonuclease I (DNASE1) | WB; IHC; ICC; IF. | |
NONE | Biotin Linked-Polyclonal Antibody to Deoxyribonuclease I (DNASE1) | ELISA(Det);IC; IH; IH(P); WB | |
NONE | APC Linked-Polyclonal Antibody to Deoxyribonuclease I (DNASE1) | IHC, WB | |
NONE | HRP Linked-Polyclonal Antibody to Deoxyribonuclease I (DNASE1) | Simple Western; WB | |
NONE | PE Linked-Polyclonal Antibody to Deoxyribonuclease I (DNASE1) | Flow Cytometry | |
NONE | FITC Linked-Polyclonal Antibody to Deoxyribonuclease I (DNASE1) | Flow Cytometry;ICC/IF | |
Assay Kits | NONE | ELISA Kit for Deoxyribonuclease I (DNASE1) | Enzyme-linked immunosorbent assay for Antigen Detection |
NONE | CLIA kit for Deoxyribonuclease I (DNASE1) | CLIA assay for Antigen Detection |
Organism species: Capra hircus; Caprine (Goat)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | NONE | Recombinant Deoxyribonuclease I (DNASE1) | Positive Control; Immunogen; SDS-PAGE; WB. |
NONE | Native Deoxyribonuclease I (DNASE1) | Bioactivity | |
Antibodies | NONE | Monoclonal Antibody to Deoxyribonuclease I (DNASE1) | WB; IHC; ICC; IP. |
NONE | Polyclonal Antibody to Deoxyribonuclease I (DNASE1) | WB; IHC; ICC; IF. | |
NONE | Biotin Linked-Polyclonal Antibody to Deoxyribonuclease I (DNASE1) | ELISA(Det);IC; IH; IH(P); WB | |
NONE | APC Linked-Polyclonal Antibody to Deoxyribonuclease I (DNASE1) | IHC, WB | |
NONE | HRP Linked-Polyclonal Antibody to Deoxyribonuclease I (DNASE1) | Simple Western; WB | |
NONE | PE Linked-Polyclonal Antibody to Deoxyribonuclease I (DNASE1) | Flow Cytometry | |
NONE | FITC Linked-Polyclonal Antibody to Deoxyribonuclease I (DNASE1) | Flow Cytometry;ICC/IF | |
Assay Kits | NONE | ELISA Kit for Deoxyribonuclease I (DNASE1) | Enzyme-linked immunosorbent assay for Antigen Detection |
NONE | CLIA kit for Deoxyribonuclease I (DNASE1) | CLIA assay for Antigen Detection |
Organism species: Pan-species (General)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | NONE | Recombinant Deoxyribonuclease I (DNASE1) | Positive Control; Immunogen; SDS-PAGE; WB. |
NONE | Native Deoxyribonuclease I (DNASE1) | Bioactivity | |
Antibodies | NONE | Monoclonal Antibody to Deoxyribonuclease I (DNASE1) | WB; IHC; ICC; IP. |
NONE | Polyclonal Antibody to Deoxyribonuclease I (DNASE1) | WB; IHC; ICC; IF. | |
NONE | Biotin Linked-Polyclonal Antibody to Deoxyribonuclease I (DNASE1) | ELISA(Det);IC; IH; IH(P); WB | |
NONE | APC Linked-Polyclonal Antibody to Deoxyribonuclease I (DNASE1) | IHC, WB | |
NONE | HRP Linked-Polyclonal Antibody to Deoxyribonuclease I (DNASE1) | Simple Western; WB | |
NONE | PE Linked-Polyclonal Antibody to Deoxyribonuclease I (DNASE1) | Flow Cytometry | |
NONE | FITC Linked-Polyclonal Antibody to Deoxyribonuclease I (DNASE1) | Flow Cytometry;ICC/IF | |
Assay Kits | NONE | ELISA Kit for Deoxyribonuclease I (DNASE1) | Enzyme-linked immunosorbent assay for Antigen Detection |
NONE | CLIA kit for Deoxyribonuclease I (DNASE1) | CLIA assay for Antigen Detection |
Reference
"Recombinant human DNase I reduces the viscosity of cystic fibrosis sputum."
Proc. Natl. Acad. Sci. U.S.A. 87:9188-9192(1990) [PubMed] [Europe PMC] [Abstract]
"Structure of the human deoxyribonuclease I (DNase I) gene: identification of the nucleotide substitution that generates its classical genetic polymorphism."
Ann. Hum. Genet. 59:1-15(1995) [PubMed] [Europe PMC] [Abstract]
"DNase I mediates internucleosomal DNA degradation in human cells undergoing drug-induced apoptosis."
Eur. J. Immunol. 31:743-751(2001) [PubMed] [Europe PMC] [Abstract]
"Characterization of human deoxyribonuclease I gene (DNASE1) promoters reveals the utilization of two transcription-starting exons and the involvement of Sp1 in its transcriptional regulation."
FEBS J. 273:3094-3105(2006) [PubMed] [Europe PMC] [Abstract]
"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
"The sequence and analysis of duplication-rich human chromosome 16."
Nature 432:988-994(2004) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"A human urine-derived interleukin 1 inhibitor. Homology with deoxyribonuclease I."
J. Exp. Med. 168:1767-1779(1988) [PubMed] [Europe PMC] [Abstract]
"Human genetically polymorphic deoxyribonuclease: purification, characterization, and multiplicity of urine deoxyribonuclease I."
J. Biochem. 108:393-398(1990) [PubMed] [Europe PMC] [Abstract]
"Mutation of DNASE1 in people with systemic lupus erythematosus."
Nat. Genet. 28:313-314(2001) [PubMed] [Europe PMC] [Abstract]
"Molecular analysis of the third allele of human deoxyribonuclease I polymorphism."
Ann. Hum. Genet. 59:139-147(1995) [PubMed] [Europe PMC] [Abstract]
"The molecular basis for genetic polymorphism of human deoxyribonuclease I: identification of the nucleotide substitution that generates the fourth allele."
FEBS Lett. 359:211-214(1995) [PubMed] [Europe PMC] [Abstract]
"The fifth allele of the human deoxyribonuclease I (DNase I) polymorphism."
Electrophoresis 18:1936-1939(1997) [PubMed] [Europe PMC] [Abstract]
"A new allele, DNASE1*6, of human deoxyribonuclease I polymorphism encodes an Arg to Cys substitution responsible for its instability."
Biochem. Biophys. Res. Commun. 260:280-283(1999) [PubMed] [Europe PMC] [Abstract]