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Cadherin, Osteoblast (CDHOB)

CDH11; CAD11; OB; OSF4; Cadherin 11 Type 2; OB-Cadherin

Cadherin-11 is type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion.

Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain.

Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV679Hu01 Recombinant Cadherin, Osteoblast (CDHOB) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV679Hu01 Monoclonal Antibody to Cadherin, Osteoblast (CDHOB) WB; IHC; ICC; IP.
PAV679Hu01 Polyclonal Antibody to Cadherin, Osteoblast (CDHOB) WB; IHC; ICC; IF.
Assay Kits CLV679Hu01 CLIA Kit for Cadherin, Osteoblast (CDHOB) CLIA assay for Antigen Detection
ELV679Hu01 ELISA Kit for Cadherin, Osteoblast (CDHOB) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV679Mu01 Recombinant Cadherin, Osteoblast (CDHOB) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV679Mu01 Monoclonal Antibody to Cadherin, Osteoblast (CDHOB) WB; IHC; ICC; IP.
PAV679Mu01 Polyclonal Antibody to Cadherin, Osteoblast (CDHOB) WB; IHC; ICC; IF.
Assay Kits CLV679Mu01 CLIA Kit for Cadherin, Osteoblast (CDHOB) CLIA assay for Antigen Detection
ELV679Mu01 ELISA Kit for Cadherin, Osteoblast (CDHOB) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV679Ra01 Recombinant Cadherin, Osteoblast (CDHOB) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV679Ra01 Monoclonal Antibody to Cadherin, Osteoblast (CDHOB) WB; IHC; ICC; IP.
PAV679Ra01 Polyclonal Antibody to Cadherin, Osteoblast (CDHOB) WB; IHC; ICC; IF.
Assay Kits CLV679Ra01 CLIA Kit for Cadherin, Osteoblast (CDHOB) CLIA assay for Antigen Detection
ELV679Ra01 ELISA Kit for Cadherin, Osteoblast (CDHOB) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV679Ca01 Recombinant Cadherin, Osteoblast (CDHOB) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV679Ca01 Monoclonal Antibody to Cadherin, Osteoblast (CDHOB) WB; IHC; ICC; IP.
PAV679Ca01 Polyclonal Antibody to Cadherin, Osteoblast (CDHOB) WB; IHC; ICC; IF.
Assay Kits CLV679Ca01 CLIA Kit for Cadherin, Osteoblast (CDHOB) CLIA assay for Antigen Detection
ELV679Ca01 ELISA Kit for Cadherin, Osteoblast (CDHOB) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV679Po01 Recombinant Cadherin, Osteoblast (CDHOB) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV679Po01 Monoclonal Antibody to Cadherin, Osteoblast (CDHOB) WB; IHC; ICC; IP.
PAV679Po01 Polyclonal Antibody to Cadherin, Osteoblast (CDHOB) WB; IHC; ICC; IF.
Assay Kits CLV679Po01 CLIA Kit for Cadherin, Osteoblast (CDHOB) CLIA assay for Antigen Detection
ELV679Po01 ELISA Kit for Cadherin, Osteoblast (CDHOB) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV679Bo01 Recombinant Cadherin, Osteoblast (CDHOB) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV679Bo01 Monoclonal Antibody to Cadherin, Osteoblast (CDHOB) WB; IHC; ICC; IP.
PAV679Bo01 Polyclonal Antibody to Cadherin, Osteoblast (CDHOB) WB; IHC; ICC; IF.
Assay Kits CLV679Bo01 CLIA Kit for Cadherin, Osteoblast (CDHOB) CLIA assay for Antigen Detection
ELV679Bo01 ELISA Kit for Cadherin, Osteoblast (CDHOB) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV679Rb01 Recombinant Cadherin, Osteoblast (CDHOB) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV679Rb01 Monoclonal Antibody to Cadherin, Osteoblast (CDHOB) WB; IHC; ICC; IP.
PAV679Rb01 Polyclonal Antibody to Cadherin, Osteoblast (CDHOB) WB; IHC; ICC; IF.
Assay Kits CLV679Rb01 CLIA Kit for Cadherin, Osteoblast (CDHOB) CLIA assay for Antigen Detection
ELV679Rb01 ELISA Kit for Cadherin, Osteoblast (CDHOB) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV679Mo01 Recombinant Cadherin, Osteoblast (CDHOB) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV679Mo01 Monoclonal Antibody to Cadherin, Osteoblast (CDHOB) WB; IHC; ICC; IP.
PAV679Mo01 Polyclonal Antibody to Cadherin, Osteoblast (CDHOB) WB; IHC; ICC; IF.
Assay Kits CLV679Mo01 CLIA Kit for Cadherin, Osteoblast (CDHOB) CLIA assay for Antigen Detection
ELV679Mo01 ELISA Kit for Cadherin, Osteoblast (CDHOB) Enzyme-linked immunosorbent assay for Antigen Detection

Reference

"Cloning of five human cadherins clarifies characteristic features of cadherin extracellular domain and provides further evidence for two structurally different types of cadherin."
Cell Adhes. Commun. 2:15-26(1994) [PubMed] [Europe PMC] [Abstract]

"Molecular cloning and characterization of OB-cadherin, a new member of cadherin family expressed in osteoblasts."
J. Biol. Chem. 269:12092-12098(1994) [PubMed] [Europe PMC] [Abstract]

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

"The sequence and analysis of duplication-rich human chromosome 16."
Nature 432:988-994(2004) [PubMed] [Europe PMC] [Abstract]

"Diversity of the cadherin family: evidence for eight new cadherins in nervous tissue."
Cell Regul. 2:261-270(1991) [PubMed] [Europe PMC] [Abstract]

"USP6 (Tre2) fusion oncogenes in aneurysmal bone cyst."
Cancer Res. 64:1920-1923(2004) [PubMed] [Europe PMC] [Abstract]