Phospholipase A1 (PLA1)

PLA1A; ps-PLA1; NMD; Phosphatidylserine-Specific Phospholipase A1-Alpha

SPN	V671
HGNC	17661
MGI	1934677
PubMed	2317456
RGD	621261
UniProt	Q53H76
Wiki	PLA1

Phospholipase A1 is a phospholipase enzyme which removes the 1-acyl. Phospholipase A1 is a component of snake venom, but it also serves in normal metabolism to produce fatty acids from phospholipids. In melanocytic cells the Phospholipase A1 gene may be regulated by MITF.

Phosphatidylserine-specific phospholipase A1-alpha (PLA1A) acts specifically on phosphatidylserine (PS) and 1-acyl-2-lysophosphatidylserine (lyso-PS) to hydrolyze fatty acids at the sn-1 position of these phospholipids.Although PLA1A belongs to the phospholipase gene family, the predicted amino acid sequence of the rat gene product demonstrated greater homology with mammalian triglyceride lipases than with phospholipases.

Organism species: Homo sapiens (Human)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	V671Hu01	Recombinant Phospholipase A1 (PLA1)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Phospholipase A1 (PLA1)	Bioactivity
Antibodies	MV671Hu22	Monoclonal Antibody to Phospholipase A1 (PLA1)	WB; IHC; ICC; IP.
	PV671Hu01	Polyclonal Antibody to Phospholipase A1 (PLA1)	WB; IHC; ICC; IF.
	LV671Hu71	Biotin Linked-Polyclonal Antibody to Phospholipase A1 (PLA1)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Phospholipase A1 (PLA1)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Phospholipase A1 (PLA1)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Phospholipase A1 (PLA1)	Flow Cytometry
	LV671Hu82	FITC Linked-Polyclonal Antibody to Phospholipase A1 (PLA1)	Flow Cytometry;ICC/IF
Assay Kits	KEV671Hu	ELISA Kit for Phospholipase A1 (PLA1)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Phospholipase A1 (PLA1)	CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Phospholipase A1 (PLA1)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Phospholipase A1 (PLA1)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Phospholipase A1 (PLA1)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Phospholipase A1 (PLA1)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Phospholipase A1 (PLA1)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Phospholipase A1 (PLA1)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Phospholipase A1 (PLA1)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Phospholipase A1 (PLA1)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Phospholipase A1 (PLA1)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Phospholipase A1 (PLA1)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Phospholipase A1 (PLA1)	CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Phospholipase A1 (PLA1)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Phospholipase A1 (PLA1)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Phospholipase A1 (PLA1)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Phospholipase A1 (PLA1)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Phospholipase A1 (PLA1)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Phospholipase A1 (PLA1)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Phospholipase A1 (PLA1)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Phospholipase A1 (PLA1)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Phospholipase A1 (PLA1)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Phospholipase A1 (PLA1)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Phospholipase A1 (PLA1)	CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Phospholipase A1 (PLA1)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Phospholipase A1 (PLA1)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Phospholipase A1 (PLA1)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Phospholipase A1 (PLA1)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Phospholipase A1 (PLA1)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Phospholipase A1 (PLA1)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Phospholipase A1 (PLA1)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Phospholipase A1 (PLA1)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Phospholipase A1 (PLA1)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Phospholipase A1 (PLA1)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Phospholipase A1 (PLA1)	CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Phospholipase A1 (PLA1)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Phospholipase A1 (PLA1)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Phospholipase A1 (PLA1)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Phospholipase A1 (PLA1)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Phospholipase A1 (PLA1)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Phospholipase A1 (PLA1)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Phospholipase A1 (PLA1)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Phospholipase A1 (PLA1)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Phospholipase A1 (PLA1)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Phospholipase A1 (PLA1)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Phospholipase A1 (PLA1)	CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Phospholipase A1 (PLA1)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Phospholipase A1 (PLA1)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Phospholipase A1 (PLA1)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Phospholipase A1 (PLA1)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Phospholipase A1 (PLA1)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Phospholipase A1 (PLA1)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Phospholipase A1 (PLA1)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Phospholipase A1 (PLA1)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Phospholipase A1 (PLA1)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Phospholipase A1 (PLA1)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Phospholipase A1 (PLA1)	CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Phospholipase A1 (PLA1)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Phospholipase A1 (PLA1)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Phospholipase A1 (PLA1)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Phospholipase A1 (PLA1)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Phospholipase A1 (PLA1)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Phospholipase A1 (PLA1)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Phospholipase A1 (PLA1)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Phospholipase A1 (PLA1)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Phospholipase A1 (PLA1)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Phospholipase A1 (PLA1)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Phospholipase A1 (PLA1)	CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Phospholipase A1 (PLA1)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Phospholipase A1 (PLA1)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Phospholipase A1 (PLA1)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Phospholipase A1 (PLA1)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Phospholipase A1 (PLA1)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Phospholipase A1 (PLA1)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Phospholipase A1 (PLA1)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Phospholipase A1 (PLA1)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Phospholipase A1 (PLA1)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Phospholipase A1 (PLA1)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Phospholipase A1 (PLA1)	CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Phospholipase A1 (PLA1)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Phospholipase A1 (PLA1)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Phospholipase A1 (PLA1)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Phospholipase A1 (PLA1)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Phospholipase A1 (PLA1)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Phospholipase A1 (PLA1)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Phospholipase A1 (PLA1)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Phospholipase A1 (PLA1)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Phospholipase A1 (PLA1)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Phospholipase A1 (PLA1)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Phospholipase A1 (PLA1)	CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Phospholipase A1 (PLA1)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Phospholipase A1 (PLA1)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Phospholipase A1 (PLA1)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Phospholipase A1 (PLA1)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Phospholipase A1 (PLA1)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Phospholipase A1 (PLA1)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Phospholipase A1 (PLA1)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Phospholipase A1 (PLA1)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Phospholipase A1 (PLA1)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Phospholipase A1 (PLA1)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Phospholipase A1 (PLA1)	CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Phospholipase A1 (PLA1)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Phospholipase A1 (PLA1)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Phospholipase A1 (PLA1)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Phospholipase A1 (PLA1)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Phospholipase A1 (PLA1)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Phospholipase A1 (PLA1)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Phospholipase A1 (PLA1)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Phospholipase A1 (PLA1)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Phospholipase A1 (PLA1)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Phospholipase A1 (PLA1)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Phospholipase A1 (PLA1)	CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Phospholipase A1 (PLA1)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Phospholipase A1 (PLA1)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Phospholipase A1 (PLA1)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Phospholipase A1 (PLA1)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Phospholipase A1 (PLA1)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Phospholipase A1 (PLA1)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Phospholipase A1 (PLA1)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Phospholipase A1 (PLA1)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Phospholipase A1 (PLA1)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Phospholipase A1 (PLA1)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Phospholipase A1 (PLA1)	CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Phospholipase A1 (PLA1)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Phospholipase A1 (PLA1)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Phospholipase A1 (PLA1)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Phospholipase A1 (PLA1)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Phospholipase A1 (PLA1)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Phospholipase A1 (PLA1)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Phospholipase A1 (PLA1)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Phospholipase A1 (PLA1)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Phospholipase A1 (PLA1)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Phospholipase A1 (PLA1)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Phospholipase A1 (PLA1)	CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Phospholipase A1 (PLA1)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Phospholipase A1 (PLA1)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Phospholipase A1 (PLA1)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Phospholipase A1 (PLA1)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Phospholipase A1 (PLA1)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Phospholipase A1 (PLA1)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Phospholipase A1 (PLA1)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Phospholipase A1 (PLA1)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Phospholipase A1 (PLA1)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Phospholipase A1 (PLA1)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Phospholipase A1 (PLA1)	CLIA assay for Antigen Detection

Reference

"nmd, a novel gene differentially expressed in human melanoma cell lines, encodes a new atypical member of the enzyme family of lipases."
FEBS Lett. 404:82-86(1997) [PubMed] [Europe PMC] [Abstract]

"An alternative splicing form of phosphatidylserine-specific phospholipase A1 that exhibits lysophosphatidylserine-specific lysophospholipase activity in humans."
J. Biol. Chem. 274:11053-11059(1999) [PubMed] [Europe PMC] [Abstract]

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

"The DNA sequence, annotation and analysis of human chromosome 3."
Nature 440:1194-1198(2006) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Polymorphisms in the gene encoding phosphatidylserine-specific phospholipase A1 (PSPLA1)."
J. Hum. Genet. 47:611-613(2002) [PubMed] [Europe PMC] [Abstract]