Integrin Alpha X (ITGaX)

CD11c; CD11-C; ITG-AX; ITGA-X; Leu M5; Complement Component 3 Receptor 4 Subunit; CD11 antigen-like family member C; Leukocyte adhesion glycoprotein p150,95 alpha chain

SPN	V663
HGNC	6152
MGI	96609
PubMed	9598326
RGD	1561123
UniProt	P20702
Wiki	ITGAX

CD11c is an integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles.

CD11c is a type I transmembrane protein found at high levels on most human dendritic cells, but also on monocytes, macrophages, neutrophils, and some B cells that induces cellular activation and helps trigger neutrophil respiratory burst; expressed in hairy cell leukemias, acute nonlymphocytic leukemias, and some B-cell chronic lymphocytic leukemias.

Organism species: Homo sapiens (Human)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	V663Hu01	Recombinant Integrin Alpha X (ITGaX)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Integrin Alpha X (ITGaX)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Integrin Alpha X (ITGaX)	WB; IHC; ICC; IP.
	PV663Hu01	Polyclonal Antibody to Integrin Alpha X (ITGaX)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Integrin Alpha X (ITGaX)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Integrin Alpha X (ITGaX)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Integrin Alpha X (ITGaX)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Integrin Alpha X (ITGaX)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Integrin Alpha X (ITGaX)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Integrin Alpha X (ITGaX)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Integrin Alpha X (ITGaX)	CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	V663Mu01	Recombinant Integrin Alpha X (ITGaX)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Integrin Alpha X (ITGaX)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Integrin Alpha X (ITGaX)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Integrin Alpha X (ITGaX)	WB; IHC; ICC; IF.
	LV663Mu71	Biotin Linked-Polyclonal Antibody to Integrin Alpha X (ITGaX)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Integrin Alpha X (ITGaX)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Integrin Alpha X (ITGaX)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Integrin Alpha X (ITGaX)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Integrin Alpha X (ITGaX)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Integrin Alpha X (ITGaX)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Integrin Alpha X (ITGaX)	CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Integrin Alpha X (ITGaX)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Integrin Alpha X (ITGaX)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Integrin Alpha X (ITGaX)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Integrin Alpha X (ITGaX)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Integrin Alpha X (ITGaX)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Integrin Alpha X (ITGaX)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Integrin Alpha X (ITGaX)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Integrin Alpha X (ITGaX)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Integrin Alpha X (ITGaX)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Integrin Alpha X (ITGaX)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Integrin Alpha X (ITGaX)	CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Integrin Alpha X (ITGaX)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Integrin Alpha X (ITGaX)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Integrin Alpha X (ITGaX)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Integrin Alpha X (ITGaX)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Integrin Alpha X (ITGaX)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Integrin Alpha X (ITGaX)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Integrin Alpha X (ITGaX)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Integrin Alpha X (ITGaX)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Integrin Alpha X (ITGaX)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Integrin Alpha X (ITGaX)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Integrin Alpha X (ITGaX)	CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Integrin Alpha X (ITGaX)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Integrin Alpha X (ITGaX)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Integrin Alpha X (ITGaX)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Integrin Alpha X (ITGaX)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Integrin Alpha X (ITGaX)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Integrin Alpha X (ITGaX)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Integrin Alpha X (ITGaX)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Integrin Alpha X (ITGaX)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Integrin Alpha X (ITGaX)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Integrin Alpha X (ITGaX)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Integrin Alpha X (ITGaX)	CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Integrin Alpha X (ITGaX)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Integrin Alpha X (ITGaX)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Integrin Alpha X (ITGaX)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Integrin Alpha X (ITGaX)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Integrin Alpha X (ITGaX)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Integrin Alpha X (ITGaX)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Integrin Alpha X (ITGaX)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Integrin Alpha X (ITGaX)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Integrin Alpha X (ITGaX)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Integrin Alpha X (ITGaX)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Integrin Alpha X (ITGaX)	CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Integrin Alpha X (ITGaX)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Integrin Alpha X (ITGaX)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Integrin Alpha X (ITGaX)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Integrin Alpha X (ITGaX)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Integrin Alpha X (ITGaX)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Integrin Alpha X (ITGaX)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Integrin Alpha X (ITGaX)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Integrin Alpha X (ITGaX)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Integrin Alpha X (ITGaX)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Integrin Alpha X (ITGaX)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Integrin Alpha X (ITGaX)	CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Integrin Alpha X (ITGaX)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Integrin Alpha X (ITGaX)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Integrin Alpha X (ITGaX)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Integrin Alpha X (ITGaX)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Integrin Alpha X (ITGaX)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Integrin Alpha X (ITGaX)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Integrin Alpha X (ITGaX)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Integrin Alpha X (ITGaX)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Integrin Alpha X (ITGaX)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Integrin Alpha X (ITGaX)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Integrin Alpha X (ITGaX)	CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Integrin Alpha X (ITGaX)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Integrin Alpha X (ITGaX)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Integrin Alpha X (ITGaX)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Integrin Alpha X (ITGaX)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Integrin Alpha X (ITGaX)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Integrin Alpha X (ITGaX)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Integrin Alpha X (ITGaX)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Integrin Alpha X (ITGaX)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Integrin Alpha X (ITGaX)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Integrin Alpha X (ITGaX)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Integrin Alpha X (ITGaX)	CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Integrin Alpha X (ITGaX)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Integrin Alpha X (ITGaX)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Integrin Alpha X (ITGaX)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Integrin Alpha X (ITGaX)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Integrin Alpha X (ITGaX)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Integrin Alpha X (ITGaX)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Integrin Alpha X (ITGaX)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Integrin Alpha X (ITGaX)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Integrin Alpha X (ITGaX)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Integrin Alpha X (ITGaX)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Integrin Alpha X (ITGaX)	CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Integrin Alpha X (ITGaX)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Integrin Alpha X (ITGaX)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Integrin Alpha X (ITGaX)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Integrin Alpha X (ITGaX)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Integrin Alpha X (ITGaX)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Integrin Alpha X (ITGaX)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Integrin Alpha X (ITGaX)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Integrin Alpha X (ITGaX)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Integrin Alpha X (ITGaX)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Integrin Alpha X (ITGaX)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Integrin Alpha X (ITGaX)	CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Integrin Alpha X (ITGaX)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Integrin Alpha X (ITGaX)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Integrin Alpha X (ITGaX)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Integrin Alpha X (ITGaX)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Integrin Alpha X (ITGaX)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Integrin Alpha X (ITGaX)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Integrin Alpha X (ITGaX)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Integrin Alpha X (ITGaX)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Integrin Alpha X (ITGaX)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Integrin Alpha X (ITGaX)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Integrin Alpha X (ITGaX)	CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Integrin Alpha X (ITGaX)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Integrin Alpha X (ITGaX)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Integrin Alpha X (ITGaX)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Integrin Alpha X (ITGaX)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Integrin Alpha X (ITGaX)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Integrin Alpha X (ITGaX)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Integrin Alpha X (ITGaX)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Integrin Alpha X (ITGaX)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Integrin Alpha X (ITGaX)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Integrin Alpha X (ITGaX)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Integrin Alpha X (ITGaX)	CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Integrin Alpha X (ITGaX)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Integrin Alpha X (ITGaX)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Integrin Alpha X (ITGaX)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Integrin Alpha X (ITGaX)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Integrin Alpha X (ITGaX)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Integrin Alpha X (ITGaX)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Integrin Alpha X (ITGaX)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Integrin Alpha X (ITGaX)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Integrin Alpha X (ITGaX)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Integrin Alpha X (ITGaX)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Integrin Alpha X (ITGaX)	CLIA assay for Antigen Detection

Reference

"cDNA cloning and complete primary structure of the alpha subunit of a leukocyte adhesion glycoprotein, p150,95."
EMBO J. 6:4023-4028(1987) [PubMed] [Europe PMC] [Abstract]

"Genomic structure of an integrin alpha subunit, the leukocyte p150,95 molecule."
J. Biol. Chem. 265:2782-2788(1990) [PubMed] [Europe PMC] [Abstract]

Erratum
J. Biol. Chem. 265:12750-12751(1990)

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Purification and alpha subunit N-terminal sequences of human Mac-1 and p150,95 leukocyte adhesion proteins."
J. Immunol. 138:2381-2383(1987) [PubMed] [Europe PMC] [Abstract]

"Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."
J. Proteome Res. 8:651-661(2009) [PubMed] [Europe PMC] [Abstract]

"Structure of an integrin with an alphaI domain, complement receptor type 4."
EMBO J. 29:666-679(2010) [PubMed] [Europe PMC] [Abstract]

"Structure and binding interface of the cytosolic tails of alphaXbeta2 integrin."
PLoS ONE 7:E41924-E41924(2012) [PubMed] [Europe PMC] [Abstract]

"VPS35 mutations in Parkinson disease."
Am. J. Hum. Genet. 89:162-167(2011) [PubMed] [Europe PMC] [Abstract]