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Granzyme K (GZMK)
Granzyme K (GZMK)
GZM-K; TRYP2; PRSS; Serine Protease,Granzyme 3; Tryptase II; Fragmentin-3; Granzyme-3; NK-tryptase-2
Granzyme K is a member of a group of related serine proteases from the cytoplasmic granules of cytotoxic lymphocytes. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here lacks consensus sequences for N-glycosylation present in other granzymes.Both the rat and the human equivalent gene TRYP2 shared considerable homology and common serine protease sequence features with human granzyme A . By fluorescence in situ hybridization, Baker et al. (1994) demonstrated that the TRYP2 gene, like HFSP, maps to 5q11-q12.
Organism species: Homo sapiens (Human)
Organism species: Mus musculus (Mouse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
V615Mu01
Recombinant Granzyme K (GZMK) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Granzyme K (GZMK) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Granzyme K (GZMK) WB; IHC; ICC; IP.
PV615Mu01
Polyclonal Antibody to Granzyme K (GZMK) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Granzyme K (GZMK) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Granzyme K (GZMK) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Granzyme K (GZMK) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Granzyme K (GZMK) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Granzyme K (GZMK) Flow Cytometry;ICC/IF
Assay Kits
KEV615Mu
ELISA Kit for Granzyme K (GZMK) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Granzyme K (GZMK) CLIA assay for Antigen Detection
Organism species: Rattus norvegicus (Rat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Granzyme K (GZMK) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Granzyme K (GZMK) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Granzyme K (GZMK) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Granzyme K (GZMK) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Granzyme K (GZMK) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Granzyme K (GZMK) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Granzyme K (GZMK) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Granzyme K (GZMK) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Granzyme K (GZMK) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Granzyme K (GZMK) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Granzyme K (GZMK) CLIA assay for Antigen Detection
Organism species: Canis familiaris; Canine (Dog)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Granzyme K (GZMK) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Granzyme K (GZMK) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Granzyme K (GZMK) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Granzyme K (GZMK) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Granzyme K (GZMK) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Granzyme K (GZMK) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Granzyme K (GZMK) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Granzyme K (GZMK) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Granzyme K (GZMK) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Granzyme K (GZMK) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Granzyme K (GZMK) CLIA assay for Antigen Detection
Organism species: Sus scrofa; Porcine (Pig)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Granzyme K (GZMK) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Granzyme K (GZMK) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Granzyme K (GZMK) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Granzyme K (GZMK) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Granzyme K (GZMK) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Granzyme K (GZMK) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Granzyme K (GZMK) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Granzyme K (GZMK) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Granzyme K (GZMK) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Granzyme K (GZMK) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Granzyme K (GZMK) CLIA assay for Antigen Detection
Organism species: Bos taurus; Bovine (Cattle)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Granzyme K (GZMK) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Granzyme K (GZMK) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Granzyme K (GZMK) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Granzyme K (GZMK) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Granzyme K (GZMK) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Granzyme K (GZMK) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Granzyme K (GZMK) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Granzyme K (GZMK) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Granzyme K (GZMK) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Granzyme K (GZMK) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Granzyme K (GZMK) CLIA assay for Antigen Detection
Organism species: Rhesus monkey (Simian)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Granzyme K (GZMK) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Granzyme K (GZMK) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Granzyme K (GZMK) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Granzyme K (GZMK) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Granzyme K (GZMK) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Granzyme K (GZMK) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Granzyme K (GZMK) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Granzyme K (GZMK) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Granzyme K (GZMK) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Granzyme K (GZMK) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Granzyme K (GZMK) CLIA assay for Antigen Detection
Organism species: Chicken (Gallus)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Granzyme K (GZMK) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Granzyme K (GZMK) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Granzyme K (GZMK) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Granzyme K (GZMK) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Granzyme K (GZMK) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Granzyme K (GZMK) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Granzyme K (GZMK) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Granzyme K (GZMK) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Granzyme K (GZMK) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Granzyme K (GZMK) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Granzyme K (GZMK) CLIA assay for Antigen Detection
Organism species: Ovis aries; Ovine (Sheep)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Granzyme K (GZMK) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Granzyme K (GZMK) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Granzyme K (GZMK) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Granzyme K (GZMK) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Granzyme K (GZMK) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Granzyme K (GZMK) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Granzyme K (GZMK) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Granzyme K (GZMK) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Granzyme K (GZMK) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Granzyme K (GZMK) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Granzyme K (GZMK) CLIA assay for Antigen Detection
Organism species: Oryctolagus cuniculus (Rabbit)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Granzyme K (GZMK) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Granzyme K (GZMK) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Granzyme K (GZMK) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Granzyme K (GZMK) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Granzyme K (GZMK) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Granzyme K (GZMK) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Granzyme K (GZMK) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Granzyme K (GZMK) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Granzyme K (GZMK) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Granzyme K (GZMK) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Granzyme K (GZMK) CLIA assay for Antigen Detection
Organism species: Cavia (Guinea pig )
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Granzyme K (GZMK) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Granzyme K (GZMK) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Granzyme K (GZMK) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Granzyme K (GZMK) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Granzyme K (GZMK) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Granzyme K (GZMK) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Granzyme K (GZMK) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Granzyme K (GZMK) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Granzyme K (GZMK) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Granzyme K (GZMK) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Granzyme K (GZMK) CLIA assay for Antigen Detection
Organism species: Equus caballus; Equine (Horse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Granzyme K (GZMK) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Granzyme K (GZMK) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Granzyme K (GZMK) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Granzyme K (GZMK) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Granzyme K (GZMK) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Granzyme K (GZMK) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Granzyme K (GZMK) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Granzyme K (GZMK) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Granzyme K (GZMK) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Granzyme K (GZMK) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Granzyme K (GZMK) CLIA assay for Antigen Detection
Organism species: Capra hircus; Caprine (Goat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Granzyme K (GZMK) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Granzyme K (GZMK) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Granzyme K (GZMK) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Granzyme K (GZMK) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Granzyme K (GZMK) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Granzyme K (GZMK) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Granzyme K (GZMK) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Granzyme K (GZMK) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Granzyme K (GZMK) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Granzyme K (GZMK) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Granzyme K (GZMK) CLIA assay for Antigen Detection
Organism species: Pan-species (General)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Granzyme K (GZMK) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Granzyme K (GZMK) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Granzyme K (GZMK) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Granzyme K (GZMK) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Granzyme K (GZMK) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Granzyme K (GZMK) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Granzyme K (GZMK) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Granzyme K (GZMK) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Granzyme K (GZMK) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Granzyme K (GZMK) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Granzyme K (GZMK) CLIA assay for Antigen Detection
Reference
"Cloning of cDNA for human granzyme 3." FEBS Lett. 364:268-271(1995) [PubMed ] [Europe PMC ] [Abstract ]
"Cloning and expression of a second human natural killer cell granule tryptase, HNK-Tryp-2/granzyme 3." PubMed ] [Europe PMC ] [Abstract ]
"Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed ] [Europe PMC ] [Abstract ]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." Genome Res. 14:2121-2127(2004) [PubMed ] [Europe PMC ] [Abstract ]
"Characterization of three serine esterases isolated from human IL-2 activated killer cells." PubMed ] [Europe PMC ] [Abstract ]
"Purification of three cytotoxic lymphocyte granule serine proteases that induce apoptosis through distinct substrate and target cell interactions." J. Exp. Med. 176:1521-1529(1992) [PubMed ] [Europe PMC ] [Abstract ]
"The 2.2-A crystal structure of human pro-granzyme K reveals a rigid zymogen with unusual features." J. Biol. Chem. 277:50923-50933(2002) [PubMed ] [Europe PMC ] [Abstract ]
