Aspartate Aminotransferase (AST)
cCAT; AAT; ASAT; SGOT; GOT1; Cysteine transaminase, cytoplasmic; Transaminase A; Aspartate Transaminase 1,Cytoplasmic; Glutamic-Oxaloacetic Transaminase 1,Soluble
AST) is similar to alanine transaminase (ALT) in that it is another enzyme associated with liver parenchymal cells.It is raised in acute liver damage. It is also present in red blood cells and cardiac muscle, skeletal muscle, and kidney and brain tissue, and may be elevated due to damage to those sources as well.AST was defined as a biochemical marker for the diagnosis of acute myocardial infarction in 1954. However the use of AST for such a diagnosis is now redundant and has been superseded by the cardiac troponins.
The 2 isoenzymes are homodimeric. In liver about 80% of the enzyme activity is mitochondrial in origin, whereas in serum the enzyme activity is largely cytosolic.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV610Hu01 | Recombinant Aspartate Aminotransferase (AST) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV610Hu01 | Monoclonal Antibody to Aspartate Aminotransferase (AST) | WB; IHC; ICC; IP. |
| PAV610Hu01 | Polyclonal Antibody to Aspartate Aminotransferase (AST) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV610Hu01 | CLIA Kit for Aspartate Aminotransferase (AST) | CLIA assay for Antigen Detection |
| ELV610Hu01 | ELISA Kit for Aspartate Aminotransferase (AST) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV610Mu01 | Recombinant Aspartate Aminotransferase (AST) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV610Mu01 | Monoclonal Antibody to Aspartate Aminotransferase (AST) | WB; IHC; ICC; IP. |
| PAV610Mu01 | Polyclonal Antibody to Aspartate Aminotransferase (AST) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV610Mu01 | CLIA Kit for Aspartate Aminotransferase (AST) | CLIA assay for Antigen Detection |
| ELV610Mu01 | ELISA Kit for Aspartate Aminotransferase (AST) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV610Ra01 | Recombinant Aspartate Aminotransferase (AST) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV610Ra01 | Monoclonal Antibody to Aspartate Aminotransferase (AST) | WB; IHC; ICC; IP. |
| PAV610Ra01 | Polyclonal Antibody to Aspartate Aminotransferase (AST) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV610Ra01 | CLIA Kit for Aspartate Aminotransferase (AST) | CLIA assay for Antigen Detection |
| ELV610Ra01 | ELISA Kit for Aspartate Aminotransferase (AST) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV610Ca01 | Recombinant Aspartate Aminotransferase (AST) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV610Ca01 | Monoclonal Antibody to Aspartate Aminotransferase (AST) | WB; IHC; ICC; IP. |
| PAV610Ca01 | Polyclonal Antibody to Aspartate Aminotransferase (AST) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV610Ca01 | CLIA Kit for Aspartate Aminotransferase (AST) | CLIA assay for Antigen Detection |
| ELV610Ca01 | ELISA Kit for Aspartate Aminotransferase (AST) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV610Po01 | Recombinant Aspartate Aminotransferase (AST) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV610Po01 | Monoclonal Antibody to Aspartate Aminotransferase (AST) | WB; IHC; ICC; IP. |
| PAV610Po01 | Polyclonal Antibody to Aspartate Aminotransferase (AST) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV610Po01 | CLIA Kit for Aspartate Aminotransferase (AST) | CLIA assay for Antigen Detection |
| ELV610Po01 | ELISA Kit for Aspartate Aminotransferase (AST) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV610Bo01 | Recombinant Aspartate Aminotransferase (AST) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV610Bo01 | Monoclonal Antibody to Aspartate Aminotransferase (AST) | WB; IHC; ICC; IP. |
| PAV610Bo01 | Polyclonal Antibody to Aspartate Aminotransferase (AST) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV610Bo01 | CLIA Kit for Aspartate Aminotransferase (AST) | CLIA assay for Antigen Detection |
| ELV610Bo01 | ELISA Kit for Aspartate Aminotransferase (AST) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV610Rb01 | Recombinant Aspartate Aminotransferase (AST) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV610Rb01 | Monoclonal Antibody to Aspartate Aminotransferase (AST) | WB; IHC; ICC; IP. |
| PAV610Rb01 | Polyclonal Antibody to Aspartate Aminotransferase (AST) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV610Rb01 | CLIA Kit for Aspartate Aminotransferase (AST) | CLIA assay for Antigen Detection |
| ELV610Rb01 | ELISA Kit for Aspartate Aminotransferase (AST) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV610Mo01 | Recombinant Aspartate Aminotransferase (AST) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV610Mo01 | Monoclonal Antibody to Aspartate Aminotransferase (AST) | WB; IHC; ICC; IP. |
| PAV610Mo01 | Polyclonal Antibody to Aspartate Aminotransferase (AST) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV610Mo01 | CLIA Kit for Aspartate Aminotransferase (AST) | CLIA assay for Antigen Detection |
| ELV610Mo01 | ELISA Kit for Aspartate Aminotransferase (AST) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
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BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
"Genome-wide association study identifies genetic variants in GOT1 determining serum aspartate aminotransferase levels."
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J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
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Submitted (AUG-2009) to the PDB data bank