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Synuclein Alpha (SNCa)

SNC-A; aSYN; PD1; PARK1; PARK4; NACP; Non-A Beta Component Of Alzheimer's Disease Amyloid Precursor Protein; Non-A4 component of amyloid precursor

  • Alpha-synuclein also known as SNCA is a protein .An alpha-synuclein fragment, known as the non-Abeta component (NAC) of Alzheimer's disease amyloid, originally found in an amyloid-enriched fraction, is shown to be a fragment of its precursor protein, NACP, by cloning of the full-length cDNA. Later, NACP turned out to be a human homologue of Torpedo synuclein. Therefore, NACP is also referred to as human alpha-synuclein.

  • Alpha-synuclein is specifically upregulated in a discrete population of presynaptic terminals of the brain during a period of acquisition-related synaptic rearrangement. It has been shown that alpha-synuclein significantly interacts with tubulin, and that alpha-synuclein may have an activity as potential microtubule-associated protein like tau.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins V602Hu01 Recombinant Synuclein Alpha (SNCa) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Synuclein Alpha (SNCa) Bioactivity
Antibodies MV602Hu22 Monoclonal Antibody to Synuclein Alpha (SNCa) WB; IHC; ICC; IP.
PV602Hu01 Polyclonal Antibody to Synuclein Alpha (SNCa) WB; IHC; ICC; IF.
LV602Hu71 Biotin Linked-Polyclonal Antibody to Synuclein Alpha (SNCa) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Synuclein Alpha (SNCa) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Synuclein Alpha (SNCa) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Synuclein Alpha (SNCa) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Synuclein Alpha (SNCa) Flow Cytometry;ICC/IF
Assay Kits KEV602Hu ELISA Kit for Synuclein Alpha (SNCa) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Synuclein Alpha (SNCa) CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins V602Mu01 Recombinant Synuclein Alpha (SNCa) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Synuclein Alpha (SNCa) Bioactivity
Antibodies NONE Monoclonal Antibody to Synuclein Alpha (SNCa) WB; IHC; ICC; IP.
PV602Mu01 Polyclonal Antibody to Synuclein Alpha (SNCa) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Synuclein Alpha (SNCa) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Synuclein Alpha (SNCa) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Synuclein Alpha (SNCa) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Synuclein Alpha (SNCa) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Synuclein Alpha (SNCa) Flow Cytometry;ICC/IF
Assay Kits KEV602Mu ELISA Kit for Synuclein Alpha (SNCa) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Synuclein Alpha (SNCa) CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Synuclein Alpha (SNCa) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Synuclein Alpha (SNCa) Bioactivity
Antibodies MV602Ra21 Monoclonal Antibody to Synuclein Alpha (SNCa) WB; IHC; ICC; IP.
PV602Ra01 Polyclonal Antibody to Synuclein Alpha (SNCa) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Synuclein Alpha (SNCa) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Synuclein Alpha (SNCa) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Synuclein Alpha (SNCa) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Synuclein Alpha (SNCa) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Synuclein Alpha (SNCa) Flow Cytometry;ICC/IF
Assay Kits KEV602Ra ELISA Kit for Synuclein Alpha (SNCa) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Synuclein Alpha (SNCa) CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Synuclein Alpha (SNCa) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Synuclein Alpha (SNCa) Bioactivity
Antibodies NONE Monoclonal Antibody to Synuclein Alpha (SNCa) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Synuclein Alpha (SNCa) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Synuclein Alpha (SNCa) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Synuclein Alpha (SNCa) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Synuclein Alpha (SNCa) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Synuclein Alpha (SNCa) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Synuclein Alpha (SNCa) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Synuclein Alpha (SNCa) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Synuclein Alpha (SNCa) CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Synuclein Alpha (SNCa) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Synuclein Alpha (SNCa) Bioactivity
Antibodies NONE Monoclonal Antibody to Synuclein Alpha (SNCa) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Synuclein Alpha (SNCa) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Synuclein Alpha (SNCa) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Synuclein Alpha (SNCa) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Synuclein Alpha (SNCa) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Synuclein Alpha (SNCa) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Synuclein Alpha (SNCa) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Synuclein Alpha (SNCa) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Synuclein Alpha (SNCa) CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Synuclein Alpha (SNCa) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Synuclein Alpha (SNCa) Bioactivity
Antibodies NONE Monoclonal Antibody to Synuclein Alpha (SNCa) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Synuclein Alpha (SNCa) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Synuclein Alpha (SNCa) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Synuclein Alpha (SNCa) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Synuclein Alpha (SNCa) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Synuclein Alpha (SNCa) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Synuclein Alpha (SNCa) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Synuclein Alpha (SNCa) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Synuclein Alpha (SNCa) CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Synuclein Alpha (SNCa) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Synuclein Alpha (SNCa) Bioactivity
Antibodies NONE Monoclonal Antibody to Synuclein Alpha (SNCa) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Synuclein Alpha (SNCa) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Synuclein Alpha (SNCa) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Synuclein Alpha (SNCa) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Synuclein Alpha (SNCa) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Synuclein Alpha (SNCa) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Synuclein Alpha (SNCa) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Synuclein Alpha (SNCa) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Synuclein Alpha (SNCa) CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Synuclein Alpha (SNCa) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Synuclein Alpha (SNCa) Bioactivity
Antibodies NONE Monoclonal Antibody to Synuclein Alpha (SNCa) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Synuclein Alpha (SNCa) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Synuclein Alpha (SNCa) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Synuclein Alpha (SNCa) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Synuclein Alpha (SNCa) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Synuclein Alpha (SNCa) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Synuclein Alpha (SNCa) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Synuclein Alpha (SNCa) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Synuclein Alpha (SNCa) CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Synuclein Alpha (SNCa) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Synuclein Alpha (SNCa) Bioactivity
Antibodies NONE Monoclonal Antibody to Synuclein Alpha (SNCa) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Synuclein Alpha (SNCa) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Synuclein Alpha (SNCa) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Synuclein Alpha (SNCa) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Synuclein Alpha (SNCa) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Synuclein Alpha (SNCa) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Synuclein Alpha (SNCa) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Synuclein Alpha (SNCa) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Synuclein Alpha (SNCa) CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Synuclein Alpha (SNCa) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Synuclein Alpha (SNCa) Bioactivity
Antibodies NONE Monoclonal Antibody to Synuclein Alpha (SNCa) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Synuclein Alpha (SNCa) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Synuclein Alpha (SNCa) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Synuclein Alpha (SNCa) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Synuclein Alpha (SNCa) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Synuclein Alpha (SNCa) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Synuclein Alpha (SNCa) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Synuclein Alpha (SNCa) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Synuclein Alpha (SNCa) CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Synuclein Alpha (SNCa) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Synuclein Alpha (SNCa) Bioactivity
Antibodies NONE Monoclonal Antibody to Synuclein Alpha (SNCa) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Synuclein Alpha (SNCa) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Synuclein Alpha (SNCa) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Synuclein Alpha (SNCa) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Synuclein Alpha (SNCa) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Synuclein Alpha (SNCa) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Synuclein Alpha (SNCa) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Synuclein Alpha (SNCa) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Synuclein Alpha (SNCa) CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Synuclein Alpha (SNCa) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Synuclein Alpha (SNCa) Bioactivity
Antibodies NONE Monoclonal Antibody to Synuclein Alpha (SNCa) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Synuclein Alpha (SNCa) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Synuclein Alpha (SNCa) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Synuclein Alpha (SNCa) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Synuclein Alpha (SNCa) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Synuclein Alpha (SNCa) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Synuclein Alpha (SNCa) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Synuclein Alpha (SNCa) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Synuclein Alpha (SNCa) CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Synuclein Alpha (SNCa) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Synuclein Alpha (SNCa) Bioactivity
Antibodies NONE Monoclonal Antibody to Synuclein Alpha (SNCa) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Synuclein Alpha (SNCa) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Synuclein Alpha (SNCa) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Synuclein Alpha (SNCa) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Synuclein Alpha (SNCa) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Synuclein Alpha (SNCa) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Synuclein Alpha (SNCa) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Synuclein Alpha (SNCa) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Synuclein Alpha (SNCa) CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Synuclein Alpha (SNCa) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Synuclein Alpha (SNCa) Bioactivity
Antibodies NONE Monoclonal Antibody to Synuclein Alpha (SNCa) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Synuclein Alpha (SNCa) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Synuclein Alpha (SNCa) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Synuclein Alpha (SNCa) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Synuclein Alpha (SNCa) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Synuclein Alpha (SNCa) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Synuclein Alpha (SNCa) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Synuclein Alpha (SNCa) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Synuclein Alpha (SNCa) CLIA assay for Antigen Detection

Reference

"Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer disease."
Proc. Natl. Acad. Sci. U.S.A. 90:11282-11286(1993) [PubMed] [Europe PMC] [Abstract]

"The NACP/synuclein gene: chromosomal assignment and screening for alterations in Alzheimer disease."
Genomics 26:254-257(1995) [PubMed] [Europe PMC] [Abstract]

"Tissue-dependent alternative splicing of mRNA for NACP, the precursor of non-A beta component of Alzheimer's disease amyloid."
Biochem. Biophys. Res. Commun. 205:1366-1372(1994) [PubMed] [Europe PMC] [Abstract]

"Human and mouse alpha-synuclein genes: comparative genomic sequence analysis and identification of a novel gene regulatory element."
Genome Res. 11:78-86(2001) [PubMed] [Europe PMC] [Abstract]

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]