Scavenger Receptor Class D Member 1 (SCARD1)
CD68; GP110; Macrosialin; Macrophage Antigen CD68
CD68 is a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. Holness and Simmons (1993) isolated cDNA clones encoding CD68 by transient expression in COS cells and immunoselection using anti-CD68 monoclonal antibodies. Two types of cDNA clones were isolated, differing by the insertion of 2 short segments in the N-terminal portion of the extracellular domain. The cDNA sequence predicted a type I integral membrane protein of 354 residues with a heavily glycosylated extracellular domain of 298 residues containing 9 potential N-linked glycosylation sites and numerous potential O-linked glycosylation sites. CD68 is a member of a family of hematopoietic mucin-like molecules that includes leukosialin/CD43 and stem cell antigen CD34 .
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV570Hu01 | Recombinant Scavenger Receptor Class D Member 1 (SCARD1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV570Hu01 | Monoclonal Antibody to Scavenger Receptor Class D Member 1 (SCARD1) | WB; IHC; ICC; IP. |
| PAV570Hu01 | Polyclonal Antibody to Scavenger Receptor Class D Member 1 (SCARD1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV570Hu01 | CLIA Kit for Scavenger Receptor Class D Member 1 (SCARD1) | CLIA assay for Antigen Detection |
| ELV570Hu01 | ELISA Kit for Scavenger Receptor Class D Member 1 (SCARD1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV570Mu01 | Recombinant Scavenger Receptor Class D Member 1 (SCARD1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV570Mu01 | Monoclonal Antibody to Scavenger Receptor Class D Member 1 (SCARD1) | WB; IHC; ICC; IP. |
| PAV570Mu01 | Polyclonal Antibody to Scavenger Receptor Class D Member 1 (SCARD1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV570Mu01 | CLIA Kit for Scavenger Receptor Class D Member 1 (SCARD1) | CLIA assay for Antigen Detection |
| ELV570Mu01 | ELISA Kit for Scavenger Receptor Class D Member 1 (SCARD1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV570Ra01 | Recombinant Scavenger Receptor Class D Member 1 (SCARD1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV570Ra01 | Monoclonal Antibody to Scavenger Receptor Class D Member 1 (SCARD1) | WB; IHC; ICC; IP. |
| PAV570Ra01 | Polyclonal Antibody to Scavenger Receptor Class D Member 1 (SCARD1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV570Ra01 | CLIA Kit for Scavenger Receptor Class D Member 1 (SCARD1) | CLIA assay for Antigen Detection |
| ELV570Ra01 | ELISA Kit for Scavenger Receptor Class D Member 1 (SCARD1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV570Ca01 | Recombinant Scavenger Receptor Class D Member 1 (SCARD1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV570Ca01 | Monoclonal Antibody to Scavenger Receptor Class D Member 1 (SCARD1) | WB; IHC; ICC; IP. |
| PAV570Ca01 | Polyclonal Antibody to Scavenger Receptor Class D Member 1 (SCARD1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV570Ca01 | CLIA Kit for Scavenger Receptor Class D Member 1 (SCARD1) | CLIA assay for Antigen Detection |
| ELV570Ca01 | ELISA Kit for Scavenger Receptor Class D Member 1 (SCARD1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV570Po01 | Recombinant Scavenger Receptor Class D Member 1 (SCARD1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV570Po01 | Monoclonal Antibody to Scavenger Receptor Class D Member 1 (SCARD1) | WB; IHC; ICC; IP. |
| PAV570Po01 | Polyclonal Antibody to Scavenger Receptor Class D Member 1 (SCARD1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV570Po01 | CLIA Kit for Scavenger Receptor Class D Member 1 (SCARD1) | CLIA assay for Antigen Detection |
| ELV570Po01 | ELISA Kit for Scavenger Receptor Class D Member 1 (SCARD1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV570Bo01 | Recombinant Scavenger Receptor Class D Member 1 (SCARD1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV570Bo01 | Monoclonal Antibody to Scavenger Receptor Class D Member 1 (SCARD1) | WB; IHC; ICC; IP. |
| PAV570Bo01 | Polyclonal Antibody to Scavenger Receptor Class D Member 1 (SCARD1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV570Bo01 | CLIA Kit for Scavenger Receptor Class D Member 1 (SCARD1) | CLIA assay for Antigen Detection |
| ELV570Bo01 | ELISA Kit for Scavenger Receptor Class D Member 1 (SCARD1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV570Rb01 | Recombinant Scavenger Receptor Class D Member 1 (SCARD1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV570Rb01 | Monoclonal Antibody to Scavenger Receptor Class D Member 1 (SCARD1) | WB; IHC; ICC; IP. |
| PAV570Rb01 | Polyclonal Antibody to Scavenger Receptor Class D Member 1 (SCARD1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV570Rb01 | CLIA Kit for Scavenger Receptor Class D Member 1 (SCARD1) | CLIA assay for Antigen Detection |
| ELV570Rb01 | ELISA Kit for Scavenger Receptor Class D Member 1 (SCARD1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV570Mo01 | Recombinant Scavenger Receptor Class D Member 1 (SCARD1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV570Mo01 | Monoclonal Antibody to Scavenger Receptor Class D Member 1 (SCARD1) | WB; IHC; ICC; IP. |
| PAV570Mo01 | Polyclonal Antibody to Scavenger Receptor Class D Member 1 (SCARD1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV570Mo01 | CLIA Kit for Scavenger Receptor Class D Member 1 (SCARD1) | CLIA assay for Antigen Detection |
| ELV570Mo01 | ELISA Kit for Scavenger Receptor Class D Member 1 (SCARD1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"Molecular cloning of CD68, a human macrophage marker related to lysosomal glycoproteins."
Blood 81:1607-1613(1993) [PubMed] [Europe PMC] [Abstract]
"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
"DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage."
Nature 440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"The linked human elongation initiation factor 4A1 (EIF4A1) and CD68 genes map to chromosome 17p13."
Genomics 53:248-250(1998) [PubMed] [Europe PMC] [Abstract]
"Macrophage specificity of three anti-CD68 monoclonal antibodies (KP1, EBM11, and PGM1) widely used for immunohistochemistry and flow cytometry."
Ann. Rheum. Dis. 63:774-784(2004) [PubMed] [Europe PMC] [Abstract]
"CD68 is not a macrophage-specific antigen."
Ann. Rheum. Dis. 64:342-343(2005) [PubMed] [Europe PMC] [Abstract]
"Elucidation of N-glycosylation sites on human platelet proteins: a glycoproteomic approach."
Mol. Cell. Proteomics 5:226-233(2006) [PubMed] [Europe PMC] [Abstract]
"Expression of CD68 in non-myeloid cell types."
Scand. J. Immunol. 67:453-463(2008) [PubMed] [Europe PMC] [Abstract]
"Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."
J. Proteome Res. 8:651-661(2009) [PubMed] [Europe PMC] [Abstract]