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Dopamine Receptor D1 (DRD1)

DR-D1; D1R; DADR; DRD1A

Dopamine is an endogenous catecholamine that influences many cellular activities, including behavior, hormone synthesis and release, blood pressure and intracellular ion transport.

DRD1 gene encodes the D1 subtype of the dopamine receptor. The D1 subtype is the most abundant dopamine receptor in the central nervous system. This G-protein coupled receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases. D1 receptors regulate neuronal growth and development, mediate some behavioral responses, and modulate dopamine receptor D2-mediated events. Alternate transcription initiation sites result in two transcript variants of this gene.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV533Hu01 Recombinant Dopamine Receptor D1 (DRD1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV533Hu01 Monoclonal Antibody to Dopamine Receptor D1 (DRD1) WB; IHC; ICC; IP.
PAV533Hu01 Polyclonal Antibody to Dopamine Receptor D1 (DRD1) WB; IHC; ICC; IF.
Assay Kits CLV533Hu01 CLIA Kit for Dopamine Receptor D1 (DRD1) CLIA assay for Antigen Detection
ELV533Hu01 ELISA Kit for Dopamine Receptor D1 (DRD1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV533Mu01 Recombinant Dopamine Receptor D1 (DRD1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV533Mu01 Monoclonal Antibody to Dopamine Receptor D1 (DRD1) WB; IHC; ICC; IP.
PAV533Mu01 Polyclonal Antibody to Dopamine Receptor D1 (DRD1) WB; IHC; ICC; IF.
Assay Kits CLV533Mu01 CLIA Kit for Dopamine Receptor D1 (DRD1) CLIA assay for Antigen Detection
ELV533Mu01 ELISA Kit for Dopamine Receptor D1 (DRD1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV533Ra01 Recombinant Dopamine Receptor D1 (DRD1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV533Ra01 Monoclonal Antibody to Dopamine Receptor D1 (DRD1) WB; IHC; ICC; IP.
PAV533Ra01 Polyclonal Antibody to Dopamine Receptor D1 (DRD1) WB; IHC; ICC; IF.
Assay Kits CLV533Ra01 CLIA Kit for Dopamine Receptor D1 (DRD1) CLIA assay for Antigen Detection
ELV533Ra01 ELISA Kit for Dopamine Receptor D1 (DRD1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV533Ca01 Recombinant Dopamine Receptor D1 (DRD1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV533Ca01 Monoclonal Antibody to Dopamine Receptor D1 (DRD1) WB; IHC; ICC; IP.
PAV533Ca01 Polyclonal Antibody to Dopamine Receptor D1 (DRD1) WB; IHC; ICC; IF.
Assay Kits CLV533Ca01 CLIA Kit for Dopamine Receptor D1 (DRD1) CLIA assay for Antigen Detection
ELV533Ca01 ELISA Kit for Dopamine Receptor D1 (DRD1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV533Po01 Recombinant Dopamine Receptor D1 (DRD1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV533Po01 Monoclonal Antibody to Dopamine Receptor D1 (DRD1) WB; IHC; ICC; IP.
PAV533Po01 Polyclonal Antibody to Dopamine Receptor D1 (DRD1) WB; IHC; ICC; IF.
Assay Kits CLV533Po01 CLIA Kit for Dopamine Receptor D1 (DRD1) CLIA assay for Antigen Detection
ELV533Po01 ELISA Kit for Dopamine Receptor D1 (DRD1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV533Bo01 Recombinant Dopamine Receptor D1 (DRD1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV533Bo01 Monoclonal Antibody to Dopamine Receptor D1 (DRD1) WB; IHC; ICC; IP.
PAV533Bo01 Polyclonal Antibody to Dopamine Receptor D1 (DRD1) WB; IHC; ICC; IF.
Assay Kits CLV533Bo01 CLIA Kit for Dopamine Receptor D1 (DRD1) CLIA assay for Antigen Detection
ELV533Bo01 ELISA Kit for Dopamine Receptor D1 (DRD1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV533Rb01 Recombinant Dopamine Receptor D1 (DRD1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV533Rb01 Monoclonal Antibody to Dopamine Receptor D1 (DRD1) WB; IHC; ICC; IP.
PAV533Rb01 Polyclonal Antibody to Dopamine Receptor D1 (DRD1) WB; IHC; ICC; IF.
Assay Kits CLV533Rb01 CLIA Kit for Dopamine Receptor D1 (DRD1) CLIA assay for Antigen Detection
ELV533Rb01 ELISA Kit for Dopamine Receptor D1 (DRD1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV533Mo01 Recombinant Dopamine Receptor D1 (DRD1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV533Mo01 Monoclonal Antibody to Dopamine Receptor D1 (DRD1) WB; IHC; ICC; IP.
PAV533Mo01 Polyclonal Antibody to Dopamine Receptor D1 (DRD1) WB; IHC; ICC; IF.
Assay Kits CLV533Mo01 CLIA Kit for Dopamine Receptor D1 (DRD1) CLIA assay for Antigen Detection
ELV533Mo01 ELISA Kit for Dopamine Receptor D1 (DRD1) Enzyme-linked immunosorbent assay for Antigen Detection

Reference

"Molecular cloning and expression of the gene for a human D1 dopamine receptor."
Nature 347:72-76(1990) [PubMed] [Europe PMC] [Abstract]

"Cloning and expression of human and rat D1 dopamine receptors."
Nature 347:76-80(1990) [PubMed] [Europe PMC] [Abstract]

"Human dopamine D1 receptor encoded by an intronless gene on chromosome 5."
Nature 347:80-83(1990) [PubMed] [Europe PMC] [Abstract]

"Schizophrenia: dopamine D1 receptor sequence is normal, but has DNA polymorphisms."
Neuropsychopharmacology 8:131-135(1993) [PubMed] [Europe PMC] [Abstract]

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Palmitoylation occurs at cysteine 347 and cysteine 351 of the dopamine D(1) receptor."
Eur. J. Pharmacol. 386:305-312(1999) [PubMed] [Europe PMC] [Abstract]

"A population-specific HTR2B stop codon predisposes to severe impulsivity."
Nature 468:1061-1066(2010) [PubMed] [Europe PMC] [Abstract]