Glycoprotein V, Platelet (GP5)

CD42-D; CD42d

SPN	V532
HGNC	4443
MGI	1096363
PubMed	11493449
RGD	2724
UniProt	P40197
Wiki	GP5

Glycoprotein V (platelet) (GP5) also known as CD42d (Cluster of Differentiation 42d), is a part of the Ib-V-IX system of surface glycoproteins that constitute the receptor for von Willebrand factor (VWF) and mediate the adhesion of platelets to injured vascular surfaces in the arterial circulation, a critical initiating event in hemostasis.

The main portion of the receptor is a heterodimer composed of 2 polypeptide chains, an alpha chain (GP1BA) and a beta chain (GP1BB), that are linked by disulfide bonds. The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX (GP9) and GP5. Mutations in GP1BA, GP1BB, and GP9 have been shown to cause Bernard-Soulier syndrome , a bleeding disorder.

Organism species: Homo sapiens (Human)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	V532Hu01	Recombinant Glycoprotein V, Platelet (GP5)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Glycoprotein V, Platelet (GP5)	Bioactivity
Antibodies	MV532Hu22	Monoclonal Antibody to Glycoprotein V, Platelet (GP5)	WB; IHC; ICC; IP.
	PV532Hu01	Polyclonal Antibody to Glycoprotein V, Platelet (GP5)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Glycoprotein V, Platelet (GP5)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Glycoprotein V, Platelet (GP5)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Glycoprotein V, Platelet (GP5)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Glycoprotein V, Platelet (GP5)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Glycoprotein V, Platelet (GP5)	Flow Cytometry;ICC/IF
Assay Kits	KEV532Hu	ELISA Kit for Glycoprotein V, Platelet (GP5)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Glycoprotein V, Platelet (GP5)	CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Glycoprotein V, Platelet (GP5)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Glycoprotein V, Platelet (GP5)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Glycoprotein V, Platelet (GP5)	WB; IHC; ICC; IP.
	PV532Mu01	Polyclonal Antibody to Glycoprotein V, Platelet (GP5)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Glycoprotein V, Platelet (GP5)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Glycoprotein V, Platelet (GP5)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Glycoprotein V, Platelet (GP5)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Glycoprotein V, Platelet (GP5)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Glycoprotein V, Platelet (GP5)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Glycoprotein V, Platelet (GP5)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Glycoprotein V, Platelet (GP5)	CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Glycoprotein V, Platelet (GP5)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Glycoprotein V, Platelet (GP5)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Glycoprotein V, Platelet (GP5)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Glycoprotein V, Platelet (GP5)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Glycoprotein V, Platelet (GP5)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Glycoprotein V, Platelet (GP5)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Glycoprotein V, Platelet (GP5)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Glycoprotein V, Platelet (GP5)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Glycoprotein V, Platelet (GP5)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Glycoprotein V, Platelet (GP5)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Glycoprotein V, Platelet (GP5)	CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Glycoprotein V, Platelet (GP5)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Glycoprotein V, Platelet (GP5)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Glycoprotein V, Platelet (GP5)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Glycoprotein V, Platelet (GP5)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Glycoprotein V, Platelet (GP5)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Glycoprotein V, Platelet (GP5)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Glycoprotein V, Platelet (GP5)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Glycoprotein V, Platelet (GP5)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Glycoprotein V, Platelet (GP5)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Glycoprotein V, Platelet (GP5)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Glycoprotein V, Platelet (GP5)	CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Glycoprotein V, Platelet (GP5)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Glycoprotein V, Platelet (GP5)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Glycoprotein V, Platelet (GP5)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Glycoprotein V, Platelet (GP5)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Glycoprotein V, Platelet (GP5)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Glycoprotein V, Platelet (GP5)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Glycoprotein V, Platelet (GP5)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Glycoprotein V, Platelet (GP5)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Glycoprotein V, Platelet (GP5)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Glycoprotein V, Platelet (GP5)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Glycoprotein V, Platelet (GP5)	CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Glycoprotein V, Platelet (GP5)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Glycoprotein V, Platelet (GP5)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Glycoprotein V, Platelet (GP5)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Glycoprotein V, Platelet (GP5)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Glycoprotein V, Platelet (GP5)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Glycoprotein V, Platelet (GP5)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Glycoprotein V, Platelet (GP5)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Glycoprotein V, Platelet (GP5)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Glycoprotein V, Platelet (GP5)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Glycoprotein V, Platelet (GP5)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Glycoprotein V, Platelet (GP5)	CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Glycoprotein V, Platelet (GP5)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Glycoprotein V, Platelet (GP5)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Glycoprotein V, Platelet (GP5)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Glycoprotein V, Platelet (GP5)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Glycoprotein V, Platelet (GP5)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Glycoprotein V, Platelet (GP5)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Glycoprotein V, Platelet (GP5)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Glycoprotein V, Platelet (GP5)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Glycoprotein V, Platelet (GP5)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Glycoprotein V, Platelet (GP5)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Glycoprotein V, Platelet (GP5)	CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Glycoprotein V, Platelet (GP5)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Glycoprotein V, Platelet (GP5)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Glycoprotein V, Platelet (GP5)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Glycoprotein V, Platelet (GP5)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Glycoprotein V, Platelet (GP5)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Glycoprotein V, Platelet (GP5)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Glycoprotein V, Platelet (GP5)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Glycoprotein V, Platelet (GP5)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Glycoprotein V, Platelet (GP5)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Glycoprotein V, Platelet (GP5)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Glycoprotein V, Platelet (GP5)	CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Glycoprotein V, Platelet (GP5)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Glycoprotein V, Platelet (GP5)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Glycoprotein V, Platelet (GP5)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Glycoprotein V, Platelet (GP5)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Glycoprotein V, Platelet (GP5)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Glycoprotein V, Platelet (GP5)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Glycoprotein V, Platelet (GP5)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Glycoprotein V, Platelet (GP5)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Glycoprotein V, Platelet (GP5)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Glycoprotein V, Platelet (GP5)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Glycoprotein V, Platelet (GP5)	CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Glycoprotein V, Platelet (GP5)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Glycoprotein V, Platelet (GP5)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Glycoprotein V, Platelet (GP5)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Glycoprotein V, Platelet (GP5)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Glycoprotein V, Platelet (GP5)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Glycoprotein V, Platelet (GP5)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Glycoprotein V, Platelet (GP5)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Glycoprotein V, Platelet (GP5)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Glycoprotein V, Platelet (GP5)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Glycoprotein V, Platelet (GP5)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Glycoprotein V, Platelet (GP5)	CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Glycoprotein V, Platelet (GP5)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Glycoprotein V, Platelet (GP5)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Glycoprotein V, Platelet (GP5)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Glycoprotein V, Platelet (GP5)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Glycoprotein V, Platelet (GP5)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Glycoprotein V, Platelet (GP5)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Glycoprotein V, Platelet (GP5)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Glycoprotein V, Platelet (GP5)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Glycoprotein V, Platelet (GP5)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Glycoprotein V, Platelet (GP5)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Glycoprotein V, Platelet (GP5)	CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Glycoprotein V, Platelet (GP5)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Glycoprotein V, Platelet (GP5)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Glycoprotein V, Platelet (GP5)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Glycoprotein V, Platelet (GP5)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Glycoprotein V, Platelet (GP5)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Glycoprotein V, Platelet (GP5)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Glycoprotein V, Platelet (GP5)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Glycoprotein V, Platelet (GP5)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Glycoprotein V, Platelet (GP5)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Glycoprotein V, Platelet (GP5)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Glycoprotein V, Platelet (GP5)	CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Glycoprotein V, Platelet (GP5)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Glycoprotein V, Platelet (GP5)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Glycoprotein V, Platelet (GP5)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Glycoprotein V, Platelet (GP5)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Glycoprotein V, Platelet (GP5)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Glycoprotein V, Platelet (GP5)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Glycoprotein V, Platelet (GP5)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Glycoprotein V, Platelet (GP5)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Glycoprotein V, Platelet (GP5)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Glycoprotein V, Platelet (GP5)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Glycoprotein V, Platelet (GP5)	CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Glycoprotein V, Platelet (GP5)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Glycoprotein V, Platelet (GP5)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Glycoprotein V, Platelet (GP5)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Glycoprotein V, Platelet (GP5)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Glycoprotein V, Platelet (GP5)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Glycoprotein V, Platelet (GP5)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Glycoprotein V, Platelet (GP5)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Glycoprotein V, Platelet (GP5)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Glycoprotein V, Platelet (GP5)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Glycoprotein V, Platelet (GP5)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Glycoprotein V, Platelet (GP5)	CLIA assay for Antigen Detection

Reference

"Human platelet glycoprotein V: characterization of the polypeptide and the related Ib-V-IX receptor system of adhesive, leucine-rich glycoproteins."
Proc. Natl. Acad. Sci. U.S.A. 90:8327-8331(1993) [PubMed] [Europe PMC] [Abstract]

"Cloning and characterization of the gene encoding the human platelet glycoprotein V. A member of the leucine-rich glycoprotein family cleaved during thrombin-induced platelet activation."
J. Biol. Chem. 268:20801-20807(1993) [PubMed] [Europe PMC] [Abstract]

"Rapid purification and characterization of human platelet glycoprotein V: the amino acid sequence contains leucine-rich repetitive modules as in glycoprotein Ib."
Blood 75:2349-2356(1990) [PubMed] [Europe PMC] [Abstract]

"Human platelet glycoprotein V: a surface leucine-rich glycoprotein related to adhesion."
Biochem. Biophys. Res. Commun. 170:153-161(1990) [PubMed] [Europe PMC] [Abstract]

"Elucidation of N-glycosylation sites on human platelet proteins: a glycoproteomic approach."
Mol. Cell. Proteomics 5:226-233(2006) [PubMed] [Europe PMC] [Abstract]

"A strategy for precise and large scale identification of core fucosylated glycoproteins."
Mol. Cell. Proteomics 8:913-923(2009) [PubMed] [Europe PMC] [Abstract]