Neurofilament 3 (NEF3)

NEFM; NF-M; NFM; Neurofilament,Medium Polypeptide; 160 kDa neurofilament protein; Neurofilament triplet M protein

SPN	V506
HGNC	7734
MGI	97314
PubMed	16734940
RGD	3160
UniProt	P07197
Wiki	NEFM

Neurofilaments are the 10 nanometer (10nm) or intermediate filaments found specifically in neurons. The subunits of neurofilaments are related structurally to the 10nm or intermediate filaments of other tissues such as the keratin subunits, which make 10nm filaments expressed specifically in epithelia.

The class III intermediate filament protein subunit peripherin is found in neurofilaments along with the class IV subunits in a few neurons, mostly in the peripheral nervous system.

The International Radiation Hybrid Mapping Consortium mapped the NEF3 gene to chromosome 8p21 found that the mouse homologs of both of these genes appear to be on chromosome 14.

Organism species: Homo sapiens (Human)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	V506Hu01	Recombinant Neurofilament 3 (NEF3)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Neurofilament 3 (NEF3)	Bioactivity
Antibodies	MV506Hu22	Monoclonal Antibody to Neurofilament 3 (NEF3)	WB; IHC; ICC; IP.
	PV506Hu01	Polyclonal Antibody to Neurofilament 3 (NEF3)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Neurofilament 3 (NEF3)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Neurofilament 3 (NEF3)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Neurofilament 3 (NEF3)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Neurofilament 3 (NEF3)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Neurofilament 3 (NEF3)	Flow Cytometry;ICC/IF
Assay Kits	KEV506Hu	ELISA Kit for Neurofilament 3 (NEF3)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Neurofilament 3 (NEF3)	CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Neurofilament 3 (NEF3)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Neurofilament 3 (NEF3)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Neurofilament 3 (NEF3)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Neurofilament 3 (NEF3)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Neurofilament 3 (NEF3)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Neurofilament 3 (NEF3)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Neurofilament 3 (NEF3)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Neurofilament 3 (NEF3)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Neurofilament 3 (NEF3)	Flow Cytometry;ICC/IF
Assay Kits	KEV506Mu	ELISA Kit for Neurofilament 3 (NEF3)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Neurofilament 3 (NEF3)	CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Neurofilament 3 (NEF3)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Neurofilament 3 (NEF3)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Neurofilament 3 (NEF3)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Neurofilament 3 (NEF3)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Neurofilament 3 (NEF3)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Neurofilament 3 (NEF3)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Neurofilament 3 (NEF3)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Neurofilament 3 (NEF3)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Neurofilament 3 (NEF3)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Neurofilament 3 (NEF3)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Neurofilament 3 (NEF3)	CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Neurofilament 3 (NEF3)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Neurofilament 3 (NEF3)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Neurofilament 3 (NEF3)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Neurofilament 3 (NEF3)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Neurofilament 3 (NEF3)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Neurofilament 3 (NEF3)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Neurofilament 3 (NEF3)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Neurofilament 3 (NEF3)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Neurofilament 3 (NEF3)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Neurofilament 3 (NEF3)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Neurofilament 3 (NEF3)	CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Neurofilament 3 (NEF3)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Neurofilament 3 (NEF3)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Neurofilament 3 (NEF3)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Neurofilament 3 (NEF3)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Neurofilament 3 (NEF3)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Neurofilament 3 (NEF3)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Neurofilament 3 (NEF3)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Neurofilament 3 (NEF3)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Neurofilament 3 (NEF3)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Neurofilament 3 (NEF3)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Neurofilament 3 (NEF3)	CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Neurofilament 3 (NEF3)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Neurofilament 3 (NEF3)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Neurofilament 3 (NEF3)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Neurofilament 3 (NEF3)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Neurofilament 3 (NEF3)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Neurofilament 3 (NEF3)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Neurofilament 3 (NEF3)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Neurofilament 3 (NEF3)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Neurofilament 3 (NEF3)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Neurofilament 3 (NEF3)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Neurofilament 3 (NEF3)	CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Neurofilament 3 (NEF3)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Neurofilament 3 (NEF3)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Neurofilament 3 (NEF3)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Neurofilament 3 (NEF3)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Neurofilament 3 (NEF3)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Neurofilament 3 (NEF3)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Neurofilament 3 (NEF3)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Neurofilament 3 (NEF3)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Neurofilament 3 (NEF3)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Neurofilament 3 (NEF3)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Neurofilament 3 (NEF3)	CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Neurofilament 3 (NEF3)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Neurofilament 3 (NEF3)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Neurofilament 3 (NEF3)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Neurofilament 3 (NEF3)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Neurofilament 3 (NEF3)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Neurofilament 3 (NEF3)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Neurofilament 3 (NEF3)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Neurofilament 3 (NEF3)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Neurofilament 3 (NEF3)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Neurofilament 3 (NEF3)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Neurofilament 3 (NEF3)	CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Neurofilament 3 (NEF3)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Neurofilament 3 (NEF3)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Neurofilament 3 (NEF3)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Neurofilament 3 (NEF3)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Neurofilament 3 (NEF3)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Neurofilament 3 (NEF3)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Neurofilament 3 (NEF3)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Neurofilament 3 (NEF3)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Neurofilament 3 (NEF3)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Neurofilament 3 (NEF3)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Neurofilament 3 (NEF3)	CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Neurofilament 3 (NEF3)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Neurofilament 3 (NEF3)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Neurofilament 3 (NEF3)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Neurofilament 3 (NEF3)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Neurofilament 3 (NEF3)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Neurofilament 3 (NEF3)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Neurofilament 3 (NEF3)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Neurofilament 3 (NEF3)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Neurofilament 3 (NEF3)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Neurofilament 3 (NEF3)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Neurofilament 3 (NEF3)	CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Neurofilament 3 (NEF3)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Neurofilament 3 (NEF3)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Neurofilament 3 (NEF3)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Neurofilament 3 (NEF3)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Neurofilament 3 (NEF3)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Neurofilament 3 (NEF3)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Neurofilament 3 (NEF3)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Neurofilament 3 (NEF3)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Neurofilament 3 (NEF3)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Neurofilament 3 (NEF3)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Neurofilament 3 (NEF3)	CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Neurofilament 3 (NEF3)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Neurofilament 3 (NEF3)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Neurofilament 3 (NEF3)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Neurofilament 3 (NEF3)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Neurofilament 3 (NEF3)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Neurofilament 3 (NEF3)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Neurofilament 3 (NEF3)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Neurofilament 3 (NEF3)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Neurofilament 3 (NEF3)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Neurofilament 3 (NEF3)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Neurofilament 3 (NEF3)	CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Neurofilament 3 (NEF3)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Neurofilament 3 (NEF3)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Neurofilament 3 (NEF3)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Neurofilament 3 (NEF3)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Neurofilament 3 (NEF3)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Neurofilament 3 (NEF3)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Neurofilament 3 (NEF3)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Neurofilament 3 (NEF3)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Neurofilament 3 (NEF3)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Neurofilament 3 (NEF3)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Neurofilament 3 (NEF3)	CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Neurofilament 3 (NEF3)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Neurofilament 3 (NEF3)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Neurofilament 3 (NEF3)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Neurofilament 3 (NEF3)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Neurofilament 3 (NEF3)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Neurofilament 3 (NEF3)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Neurofilament 3 (NEF3)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Neurofilament 3 (NEF3)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Neurofilament 3 (NEF3)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Neurofilament 3 (NEF3)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Neurofilament 3 (NEF3)	CLIA assay for Antigen Detection

Reference

"The human mid-size neurofilament subunit: a repeated protein sequence and the relationship of its gene to the intermediate filament gene family."
EMBO J. 6:1617-1626(1987) [PubMed] [Europe PMC] [Abstract]

"Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs."
Genome Res. 11:422-435(2001) [PubMed] [Europe PMC] [Abstract]

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

"DNA sequence and analysis of human chromosome 8."
Nature 439:331-335(2006) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Identification of the major multiphosphorylation site in mammalian neurofilaments."
Proc. Natl. Acad. Sci. U.S.A. 85:1998-2002(1988) [PubMed] [Europe PMC] [Abstract]