Growth Associated Protein 43 (GAP43)
F1; B-50; PP46; Neuron Growth-Associated Protein 43; Neuromodulin; Axonal Membrane Protein GAP-43; Protein F1; Calmodulin-Binding Protein P-57; Neural Phosphoprotein B-50
Growth-associated protein 43, GAP-43 is a nervous tissue specific protein which is highly expressed in neurons during development and nerve regeneration. It has been implicated in neurite outgrowth, long-term potentiation, signal transduction, and neurotransmitter release. It is also a substrate of PROTEIN KINASE C. Group of developmentally regulated polypeptides thought to be critical for the formation of neural circuitry. The acidic membrane phosphoprotein GAP 43 is synthesised and transported down regenerating and developing axons, pp46 localised in growth cone membranes during embryogenesis, B 50 in mature presynaptic membranes in the regulation of phosphotidylinositol turnover and F1 in the hippocampus during long-term potentiation, are now all known to be the same protein.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV505Hu01 | Recombinant Growth Associated Protein 43 (GAP43) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV505Hu01 | Monoclonal Antibody to Growth Associated Protein 43 (GAP43) | WB; IHC; ICC; IP. |
| PAV505Hu01 | Polyclonal Antibody to Growth Associated Protein 43 (GAP43) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV505Hu01 | CLIA Kit for Growth Associated Protein 43 (GAP43) | CLIA assay for Antigen Detection |
| ELV505Hu01 | ELISA Kit for Growth Associated Protein 43 (GAP43) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV505Mu01 | Recombinant Growth Associated Protein 43 (GAP43) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV505Mu01 | Monoclonal Antibody to Growth Associated Protein 43 (GAP43) | WB; IHC; ICC; IP. |
| PAV505Mu01 | Polyclonal Antibody to Growth Associated Protein 43 (GAP43) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV505Mu01 | CLIA Kit for Growth Associated Protein 43 (GAP43) | CLIA assay for Antigen Detection |
| ELV505Mu01 | ELISA Kit for Growth Associated Protein 43 (GAP43) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV505Ra01 | Recombinant Growth Associated Protein 43 (GAP43) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV505Ra01 | Monoclonal Antibody to Growth Associated Protein 43 (GAP43) | WB; IHC; ICC; IP. |
| PAV505Ra01 | Polyclonal Antibody to Growth Associated Protein 43 (GAP43) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV505Ra01 | CLIA Kit for Growth Associated Protein 43 (GAP43) | CLIA assay for Antigen Detection |
| ELV505Ra01 | ELISA Kit for Growth Associated Protein 43 (GAP43) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV505Ca01 | Recombinant Growth Associated Protein 43 (GAP43) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV505Ca01 | Monoclonal Antibody to Growth Associated Protein 43 (GAP43) | WB; IHC; ICC; IP. |
| PAV505Ca01 | Polyclonal Antibody to Growth Associated Protein 43 (GAP43) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV505Ca01 | CLIA Kit for Growth Associated Protein 43 (GAP43) | CLIA assay for Antigen Detection |
| ELV505Ca01 | ELISA Kit for Growth Associated Protein 43 (GAP43) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV505Po01 | Recombinant Growth Associated Protein 43 (GAP43) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV505Po01 | Monoclonal Antibody to Growth Associated Protein 43 (GAP43) | WB; IHC; ICC; IP. |
| PAV505Po01 | Polyclonal Antibody to Growth Associated Protein 43 (GAP43) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV505Po01 | CLIA Kit for Growth Associated Protein 43 (GAP43) | CLIA assay for Antigen Detection |
| ELV505Po01 | ELISA Kit for Growth Associated Protein 43 (GAP43) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV505Bo01 | Recombinant Growth Associated Protein 43 (GAP43) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV505Bo01 | Monoclonal Antibody to Growth Associated Protein 43 (GAP43) | WB; IHC; ICC; IP. |
| PAV505Bo01 | Polyclonal Antibody to Growth Associated Protein 43 (GAP43) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV505Bo01 | CLIA Kit for Growth Associated Protein 43 (GAP43) | CLIA assay for Antigen Detection |
| ELV505Bo01 | ELISA Kit for Growth Associated Protein 43 (GAP43) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV505Rb01 | Recombinant Growth Associated Protein 43 (GAP43) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV505Rb01 | Monoclonal Antibody to Growth Associated Protein 43 (GAP43) | WB; IHC; ICC; IP. |
| PAV505Rb01 | Polyclonal Antibody to Growth Associated Protein 43 (GAP43) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV505Rb01 | CLIA Kit for Growth Associated Protein 43 (GAP43) | CLIA assay for Antigen Detection |
| ELV505Rb01 | ELISA Kit for Growth Associated Protein 43 (GAP43) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV505Mo01 | Recombinant Growth Associated Protein 43 (GAP43) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV505Mo01 | Monoclonal Antibody to Growth Associated Protein 43 (GAP43) | WB; IHC; ICC; IP. |
| PAV505Mo01 | Polyclonal Antibody to Growth Associated Protein 43 (GAP43) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV505Mo01 | CLIA Kit for Growth Associated Protein 43 (GAP43) | CLIA assay for Antigen Detection |
| ELV505Mo01 | ELISA Kit for Growth Associated Protein 43 (GAP43) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"Human GAP-43: its deduced amino acid sequence and chromosomal localization in mouse and human."
Neuron 1:127-132(1988) [PubMed] [Europe PMC] [Abstract]
"Cloning of human GAP-43: growth association and ischemic resurgence."
Neuron 1:133-139(1988) [PubMed] [Europe PMC] [Abstract]
"Structure of the human gene for the neural phosphoprotein B-50 (GAP-43)."
Brain Res. Mol. Brain Res. 19:293-302(1993) [PubMed] [Europe PMC] [Abstract]
"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
"The DNA sequence, annotation and analysis of human chromosome 3."
Nature 440:1194-1198(2006) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"Regulation of dendritic branching and filopodia formation in hippocampal neurons by specific acylated protein motifs."
Mol. Biol. Cell 15:2205-2217(2004) [PubMed] [Europe PMC] [Abstract]
"Acyl-protein thioesterase 2 catalyzes the deacylation of peripheral membrane-associated GAP-43."
PLoS ONE 5:E15045-E15045(2010) [PubMed] [Europe PMC] [Abstract]
"System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
"Characterization of single-nucleotide polymorphisms in coding regions of human genes."
Nat. Genet. 22:231-238(1999) [PubMed] [Europe PMC] [Abstract]
Erratum
Nat. Genet. 23:373-373(1999)