Bcl2 Associated X Protein (Bax)
BCL2L4; Bax Zeta; Apoptosis regulator BAX; Bcl-2-like protein 4
Bax (Bcl-2 associated x protein) is an apoptosis regulating protein of the Bcl-2 family. The ratio of Bax to Bcl-2 determines survival or death following an apoptotic stimulus. Bax is implicated in many cancers, uterine leiomyomas, and brain dysmorphology. Bax is a 21 kDa protein that accelerates apoptosis by binding to, and antagonizing the death repressor activity of Bcl-2 in vivo.
Bax normally resides in the cytoplasm, but following an apoptotic stimuli, Bax undergoes a conformational change and translocates to mitochondrial membranes, where it inserts and mediates the release of cytochrome c from the intermembrane space into the cytosol, in this manner activating caspase-3 and perpetuating the apoptotic cascade.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | V490Hu01 | Recombinant Bcl2 Associated X Protein (Bax) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Bcl2 Associated X Protein (Bax) | Bioactivity | |
| Antibodies | MV490Hu22 | Monoclonal Antibody to Bcl2 Associated X Protein (Bax) | WB; IHC; ICC; IP. |
| PV490Hu01 | Polyclonal Antibody to Bcl2 Associated X Protein (Bax) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Bcl2 Associated X Protein (Bax) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Bcl2 Associated X Protein (Bax) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Bcl2 Associated X Protein (Bax) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Bcl2 Associated X Protein (Bax) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Bcl2 Associated X Protein (Bax) | Flow Cytometry;ICC/IF | |
| Assay Kits | KEV490Hu | ELISA Kit for Bcl2 Associated X Protein (Bax) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Bcl2 Associated X Protein (Bax) | CLIA assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | V490Mu02 | Recombinant Bcl2 Associated X Protein (Bax) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Bcl2 Associated X Protein (Bax) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Bcl2 Associated X Protein (Bax) | WB; IHC; ICC; IP. |
| PV490Mu01 | Polyclonal Antibody to Bcl2 Associated X Protein (Bax) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Bcl2 Associated X Protein (Bax) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Bcl2 Associated X Protein (Bax) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Bcl2 Associated X Protein (Bax) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Bcl2 Associated X Protein (Bax) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Bcl2 Associated X Protein (Bax) | Flow Cytometry;ICC/IF | |
| Assay Kits | KEV490Mu | ELISA Kit for Bcl2 Associated X Protein (Bax) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Bcl2 Associated X Protein (Bax) | CLIA assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | V490Ra01 | Recombinant Bcl2 Associated X Protein (Bax) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Bcl2 Associated X Protein (Bax) | Bioactivity | |
| Antibodies | MV490Ra21 | Monoclonal Antibody to Bcl2 Associated X Protein (Bax) | WB; IHC; ICC; IP. |
| PV490Ra01 | Polyclonal Antibody to Bcl2 Associated X Protein (Bax) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Bcl2 Associated X Protein (Bax) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Bcl2 Associated X Protein (Bax) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Bcl2 Associated X Protein (Bax) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Bcl2 Associated X Protein (Bax) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Bcl2 Associated X Protein (Bax) | Flow Cytometry;ICC/IF | |
| Assay Kits | KEV490Ra | ELISA Kit for Bcl2 Associated X Protein (Bax) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Bcl2 Associated X Protein (Bax) | CLIA assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Bcl2 Associated X Protein (Bax) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Bcl2 Associated X Protein (Bax) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Bcl2 Associated X Protein (Bax) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Bcl2 Associated X Protein (Bax) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Bcl2 Associated X Protein (Bax) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Bcl2 Associated X Protein (Bax) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Bcl2 Associated X Protein (Bax) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Bcl2 Associated X Protein (Bax) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Bcl2 Associated X Protein (Bax) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Bcl2 Associated X Protein (Bax) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Bcl2 Associated X Protein (Bax) | CLIA assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | V490Po01 | Recombinant Bcl2 Associated X Protein (Bax) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Bcl2 Associated X Protein (Bax) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Bcl2 Associated X Protein (Bax) | WB; IHC; ICC; IP. |
| PV490Po01 | Polyclonal Antibody to Bcl2 Associated X Protein (Bax) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Bcl2 Associated X Protein (Bax) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Bcl2 Associated X Protein (Bax) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Bcl2 Associated X Protein (Bax) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Bcl2 Associated X Protein (Bax) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Bcl2 Associated X Protein (Bax) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Bcl2 Associated X Protein (Bax) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Bcl2 Associated X Protein (Bax) | CLIA assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | V490Bo01 | Recombinant Bcl2 Associated X Protein (Bax) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Bcl2 Associated X Protein (Bax) | Bioactivity | |
| Antibodies | MV490Bo21 | Monoclonal Antibody to Bcl2 Associated X Protein (Bax) | WB; IHC; ICC; IP. |
| PV490Bo01 | Polyclonal Antibody to Bcl2 Associated X Protein (Bax) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Bcl2 Associated X Protein (Bax) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Bcl2 Associated X Protein (Bax) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Bcl2 Associated X Protein (Bax) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Bcl2 Associated X Protein (Bax) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Bcl2 Associated X Protein (Bax) | Flow Cytometry;ICC/IF | |
| Assay Kits | KEV490Bo | ELISA Kit for Bcl2 Associated X Protein (Bax) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Bcl2 Associated X Protein (Bax) | CLIA assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Bcl2 Associated X Protein (Bax) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Bcl2 Associated X Protein (Bax) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Bcl2 Associated X Protein (Bax) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Bcl2 Associated X Protein (Bax) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Bcl2 Associated X Protein (Bax) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Bcl2 Associated X Protein (Bax) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Bcl2 Associated X Protein (Bax) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Bcl2 Associated X Protein (Bax) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Bcl2 Associated X Protein (Bax) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Bcl2 Associated X Protein (Bax) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Bcl2 Associated X Protein (Bax) | CLIA assay for Antigen Detection |
Organism species: Chicken (Gallus)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Bcl2 Associated X Protein (Bax) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Bcl2 Associated X Protein (Bax) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Bcl2 Associated X Protein (Bax) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Bcl2 Associated X Protein (Bax) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Bcl2 Associated X Protein (Bax) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Bcl2 Associated X Protein (Bax) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Bcl2 Associated X Protein (Bax) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Bcl2 Associated X Protein (Bax) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Bcl2 Associated X Protein (Bax) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Bcl2 Associated X Protein (Bax) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Bcl2 Associated X Protein (Bax) | CLIA assay for Antigen Detection |
Organism species: Ovis aries; Ovine (Sheep)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Bcl2 Associated X Protein (Bax) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Bcl2 Associated X Protein (Bax) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Bcl2 Associated X Protein (Bax) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Bcl2 Associated X Protein (Bax) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Bcl2 Associated X Protein (Bax) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Bcl2 Associated X Protein (Bax) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Bcl2 Associated X Protein (Bax) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Bcl2 Associated X Protein (Bax) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Bcl2 Associated X Protein (Bax) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Bcl2 Associated X Protein (Bax) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Bcl2 Associated X Protein (Bax) | CLIA assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Bcl2 Associated X Protein (Bax) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Bcl2 Associated X Protein (Bax) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Bcl2 Associated X Protein (Bax) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Bcl2 Associated X Protein (Bax) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Bcl2 Associated X Protein (Bax) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Bcl2 Associated X Protein (Bax) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Bcl2 Associated X Protein (Bax) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Bcl2 Associated X Protein (Bax) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Bcl2 Associated X Protein (Bax) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Bcl2 Associated X Protein (Bax) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Bcl2 Associated X Protein (Bax) | CLIA assay for Antigen Detection |
Organism species: Cavia (Guinea pig )
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Bcl2 Associated X Protein (Bax) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Bcl2 Associated X Protein (Bax) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Bcl2 Associated X Protein (Bax) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Bcl2 Associated X Protein (Bax) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Bcl2 Associated X Protein (Bax) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Bcl2 Associated X Protein (Bax) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Bcl2 Associated X Protein (Bax) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Bcl2 Associated X Protein (Bax) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Bcl2 Associated X Protein (Bax) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Bcl2 Associated X Protein (Bax) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Bcl2 Associated X Protein (Bax) | CLIA assay for Antigen Detection |
Organism species: Equus caballus; Equine (Horse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Bcl2 Associated X Protein (Bax) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Bcl2 Associated X Protein (Bax) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Bcl2 Associated X Protein (Bax) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Bcl2 Associated X Protein (Bax) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Bcl2 Associated X Protein (Bax) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Bcl2 Associated X Protein (Bax) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Bcl2 Associated X Protein (Bax) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Bcl2 Associated X Protein (Bax) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Bcl2 Associated X Protein (Bax) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Bcl2 Associated X Protein (Bax) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Bcl2 Associated X Protein (Bax) | CLIA assay for Antigen Detection |
Organism species: Capra hircus; Caprine (Goat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Bcl2 Associated X Protein (Bax) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Bcl2 Associated X Protein (Bax) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Bcl2 Associated X Protein (Bax) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Bcl2 Associated X Protein (Bax) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Bcl2 Associated X Protein (Bax) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Bcl2 Associated X Protein (Bax) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Bcl2 Associated X Protein (Bax) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Bcl2 Associated X Protein (Bax) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Bcl2 Associated X Protein (Bax) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Bcl2 Associated X Protein (Bax) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Bcl2 Associated X Protein (Bax) | CLIA assay for Antigen Detection |
Organism species: Pan-species (General)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Bcl2 Associated X Protein (Bax) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Bcl2 Associated X Protein (Bax) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Bcl2 Associated X Protein (Bax) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Bcl2 Associated X Protein (Bax) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Bcl2 Associated X Protein (Bax) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Bcl2 Associated X Protein (Bax) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Bcl2 Associated X Protein (Bax) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Bcl2 Associated X Protein (Bax) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Bcl2 Associated X Protein (Bax) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Bcl2 Associated X Protein (Bax) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Bcl2 Associated X Protein (Bax) | CLIA assay for Antigen Detection |
Reference
"Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death."
Cell 74:609-619(1993) [PubMed] [Europe PMC] [Abstract]
"Mapping of the human BAX gene to chromosome 19q13.3-q13.4 and isolation of a novel alternatively spliced transcript, BAX delta."
Genomics 26:592-594(1995) [PubMed] [Europe PMC] [Abstract]
"Identification and characterization of baxepsilon, a novel bax variant missing the BH2 and the transmembrane domains."
Biochem. Biophys. Res. Commun. 254:779-785(1999) [PubMed] [Europe PMC] [Abstract]
"Characterization of Bax-sigma, a cell death-inducing isoform of Bax."
Biochem. Biophys. Res. Commun. 270:868-879(2000) [PubMed] [Europe PMC] [Abstract]
"The expression of a new variant of the pro-apoptotic molecule Bax, Baxpsi, is correlated with an increased survival of glioblastoma multiforme patients."
Hum. Mol. Genet. 11:675-687(2002) [PubMed] [Europe PMC] [Abstract]
"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"Bax mutations in cell lines derived from hematological malignancies."
Leukemia 9:1828-1832(1995) [PubMed] [Europe PMC] [Abstract]
"A conserved domain in Bak, distinct from BH1 and BH2, mediates cell death and protein binding functions."
EMBO J. 14:5589-5596(1995) [PubMed] [Europe PMC] [Abstract]
"Conformation of the Bax C-terminus regulates subcellular location and cell death."
EMBO J. 18:2330-2341(1999) [PubMed] [Europe PMC] [Abstract]
"Molecular cloning and characterization of Bif-1. A novel Src homology 3 domain-containing protein that associates with Bax."
J. Biol. Chem. 276:20559-20565(2001) [PubMed] [Europe PMC] [Abstract]
"Humanin peptide suppresses apoptosis by interfering with Bax activation."
Nature 423:456-461(2003) [PubMed] [Europe PMC] [Abstract]
"JNK promotes Bax translocation to mitochondria through phosphorylation of 14-3-3 proteins."
EMBO J. 23:1889-1899(2004) [PubMed] [Europe PMC] [Abstract]
"Apoptosis repressor with caspase recruitment domain protects against cell death by interfering with Bax activation."
J. Biol. Chem. 279:21233-21238(2004) [PubMed] [Europe PMC] [Abstract]
"An anti-apoptotic viral protein that recruits Bax to mitochondria."
J. Biol. Chem. 279:22605-22614(2004) [PubMed] [Europe PMC] [Abstract]
"Clusterin inhibits apoptosis by interacting with activated Bax."
Nat. Cell Biol. 7:909-915(2005) [PubMed] [Europe PMC] [Abstract]
"Sequence analysis shows that Lifeguard belongs to a new evolutionarily conserved cytoprotective family."
Int. J. Mol. Med. 18:729-734(2006) [PubMed] [Europe PMC] [Abstract]
"Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
"IBRDC2, an IBR-type E3 ubiquitin ligase, is a regulatory factor for Bax and apoptosis activation."
EMBO J. 29:1458-1471(2010) [PubMed] [Europe PMC] [Abstract]
"Initial characterization of the human central proteome."
BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
"Human Bop is a novel BH3-only member of the Bcl-2 protein family."
Protein Cell 3:790-801(2012) [PubMed] [Europe PMC] [Abstract]
"Structure of Bax: coregulation of dimer formation and intracellular localization."
Cell 103:645-654(2000) [PubMed] [Europe PMC] [Abstract]
"Elucidation of some Bax conformational changes through crystallization of an antibody-peptide complex."
Cell Death Differ. 14:447-452(2007) [PubMed] [Europe PMC] [Abstract]
"BAX activation is initiated at a novel interaction site."
Nature 455:1076-1081(2008) [PubMed] [Europe PMC] [Abstract]
"Mutation to Bax beyond the BH3 domain disrupts interactions with pro-survival proteins and promotes apoptosis."
J. Biol. Chem. 286:7123-7131(2011) [PubMed] [Europe PMC] [Abstract]
"Hematopoietic malignancies demonstrate loss-of-function mutations of BAX."
Blood 91:2991-2997(1998) [PubMed] [Europe PMC] [Abstract]