Actin Gamma 2, Smooth Muscle (ACTg2)
ACT; ACT-G2; ACTA3; ACTE; ACTL3; ACTSG; Alpha-actin-3
Actin, gamma-enteric smooth muscle is a protein encoded by the ACTG2 gene.Actins are highly conserved proteins that are involved in various types of cell motility, and maintenance of the cytoskeleton. In vertebrates, three main groups of actin isoforms, alpha, beta and gamma have been identified.
The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins co-exist in most cell types as components of the cytoskeleton, and as mediators of internal cell motility. Actin, gamma 2, encoded by this gene, is a smooth muscle actin found in enteric tissues.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV489Hu01 | Recombinant Actin Gamma 2, Smooth Muscle (ACTg2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV489Hu01 | Monoclonal Antibody to Actin Gamma 2, Smooth Muscle (ACTg2) | WB; IHC; ICC; IP. |
| PAV489Hu01 | Polyclonal Antibody to Actin Gamma 2, Smooth Muscle (ACTg2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV489Hu01 | CLIA Kit for Actin Gamma 2, Smooth Muscle (ACTg2) | CLIA assay for Antigen Detection |
| ELV489Hu01 | ELISA Kit for Actin Gamma 2, Smooth Muscle (ACTg2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV489Mu01 | Recombinant Actin Gamma 2, Smooth Muscle (ACTg2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV489Mu01 | Monoclonal Antibody to Actin Gamma 2, Smooth Muscle (ACTg2) | WB; IHC; ICC; IP. |
| PAV489Mu01 | Polyclonal Antibody to Actin Gamma 2, Smooth Muscle (ACTg2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV489Mu01 | CLIA Kit for Actin Gamma 2, Smooth Muscle (ACTg2) | CLIA assay for Antigen Detection |
| ELV489Mu01 | ELISA Kit for Actin Gamma 2, Smooth Muscle (ACTg2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV489Ra01 | Recombinant Actin Gamma 2, Smooth Muscle (ACTg2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV489Ra01 | Monoclonal Antibody to Actin Gamma 2, Smooth Muscle (ACTg2) | WB; IHC; ICC; IP. |
| PAV489Ra01 | Polyclonal Antibody to Actin Gamma 2, Smooth Muscle (ACTg2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV489Ra01 | CLIA Kit for Actin Gamma 2, Smooth Muscle (ACTg2) | CLIA assay for Antigen Detection |
| ELV489Ra01 | ELISA Kit for Actin Gamma 2, Smooth Muscle (ACTg2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV489Ca01 | Recombinant Actin Gamma 2, Smooth Muscle (ACTg2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV489Ca01 | Monoclonal Antibody to Actin Gamma 2, Smooth Muscle (ACTg2) | WB; IHC; ICC; IP. |
| PAV489Ca01 | Polyclonal Antibody to Actin Gamma 2, Smooth Muscle (ACTg2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV489Ca01 | CLIA Kit for Actin Gamma 2, Smooth Muscle (ACTg2) | CLIA assay for Antigen Detection |
| ELV489Ca01 | ELISA Kit for Actin Gamma 2, Smooth Muscle (ACTg2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV489Po01 | Recombinant Actin Gamma 2, Smooth Muscle (ACTg2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV489Po01 | Monoclonal Antibody to Actin Gamma 2, Smooth Muscle (ACTg2) | WB; IHC; ICC; IP. |
| PAV489Po01 | Polyclonal Antibody to Actin Gamma 2, Smooth Muscle (ACTg2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV489Po01 | CLIA Kit for Actin Gamma 2, Smooth Muscle (ACTg2) | CLIA assay for Antigen Detection |
| ELV489Po01 | ELISA Kit for Actin Gamma 2, Smooth Muscle (ACTg2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV489Bo01 | Recombinant Actin Gamma 2, Smooth Muscle (ACTg2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV489Bo01 | Monoclonal Antibody to Actin Gamma 2, Smooth Muscle (ACTg2) | WB; IHC; ICC; IP. |
| PAV489Bo01 | Polyclonal Antibody to Actin Gamma 2, Smooth Muscle (ACTg2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV489Bo01 | CLIA Kit for Actin Gamma 2, Smooth Muscle (ACTg2) | CLIA assay for Antigen Detection |
| ELV489Bo01 | ELISA Kit for Actin Gamma 2, Smooth Muscle (ACTg2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV489Rb01 | Recombinant Actin Gamma 2, Smooth Muscle (ACTg2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV489Rb01 | Monoclonal Antibody to Actin Gamma 2, Smooth Muscle (ACTg2) | WB; IHC; ICC; IP. |
| PAV489Rb01 | Polyclonal Antibody to Actin Gamma 2, Smooth Muscle (ACTg2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV489Rb01 | CLIA Kit for Actin Gamma 2, Smooth Muscle (ACTg2) | CLIA assay for Antigen Detection |
| ELV489Rb01 | ELISA Kit for Actin Gamma 2, Smooth Muscle (ACTg2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV489Mo01 | Recombinant Actin Gamma 2, Smooth Muscle (ACTg2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV489Mo01 | Monoclonal Antibody to Actin Gamma 2, Smooth Muscle (ACTg2) | WB; IHC; ICC; IP. |
| PAV489Mo01 | Polyclonal Antibody to Actin Gamma 2, Smooth Muscle (ACTg2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV489Mo01 | CLIA Kit for Actin Gamma 2, Smooth Muscle (ACTg2) | CLIA assay for Antigen Detection |
| ELV489Mo01 | ELISA Kit for Actin Gamma 2, Smooth Muscle (ACTg2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"The nucleotide sequence of a human smooth muscle (enteric type) gamma-actin cDNA."
Nucleic Acids Res. 18:4263-4263(1990) [PubMed] [Europe PMC] [Abstract]
"Structure, chromosome location, and expression of the human smooth muscle (enteric type) gamma-actin gene: evolution of six human actin genes."
Mol. Cell. Biol. 11:3296-3306(1991) [PubMed] [Europe PMC] [Abstract]
"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
"Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"Segregation of a missense variant in enteric smooth muscle actin gamma-2 with autosomal dominant familial visceral myopathy."
Gastroenterology 143:1482-1491(2012) [PubMed] [Europe PMC] [Abstract]
"Familial visceral myopathy diagnosed by exome sequencing of a patient with chronic intestinal pseudo-obstruction."
Endoscopy 46:533-537(2014) [PubMed] [Europe PMC] [Abstract]
"De novo ACTG2 mutations cause congenital distended bladder, microcolon, and intestinal hypoperistalsis."
Hum. Genet. 133:737-742(2014) [PubMed] [Europe PMC] [Abstract]
"Heterozygous de novo and inherited mutations in the smooth muscle actin (ACTG2) gene underlie megacystis-microcolon-intestinal hypoperistalsis syndrome."
PLoS Genet. 10:E1004258-E1004258(2014) [PubMed] [Europe PMC] [Abstract]