Von Willebrand Factor A Domain Containing Protein 2 (vWA2)
AMACO; VWFA2; CCSP-2; A Domain-Containing Protein Similar To Matrilin And Collagen; Colon cancer secreted protein 2
von Willebrand factor A domain-containing protein 2, also known as A domain-containing protein similar to matrilin and collagen (AMACO) is a member of the von Willebrand factor A-like (VWA) domain containing protein superfamily and consists of three VWA-like domains, two EGF-like domains, a cysteine-rich domain and a unique C-terminal domain. AMACO is an extracellular matrix protein and mostly deposited adjacent to basement membranes.
Expression is generally absent in normal colon and other normal body tissues, but it is induced an average of 78-fold in Stage II, III, and IV colon cancers, as well as in colon adenomas and colon cancer cell lines. it was found markedly induced in colon cancers and may be useful diagnostic serum marker.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV445Hu01 | Recombinant Von Willebrand Factor A Domain Containing Protein 2 (vWA2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV445Hu01 | Monoclonal Antibody to Von Willebrand Factor A Domain Containing Protein 2 (vWA2) | WB; IHC; ICC; IP. |
| PAV445Hu01 | Polyclonal Antibody to Von Willebrand Factor A Domain Containing Protein 2 (vWA2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV445Hu01 | CLIA Kit for Von Willebrand Factor A Domain Containing Protein 2 (vWA2) | CLIA assay for Antigen Detection |
| ELV445Hu01 | ELISA Kit for Von Willebrand Factor A Domain Containing Protein 2 (vWA2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV445Mu01 | Recombinant Von Willebrand Factor A Domain Containing Protein 2 (vWA2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV445Mu01 | Monoclonal Antibody to Von Willebrand Factor A Domain Containing Protein 2 (vWA2) | WB; IHC; ICC; IP. |
| PAV445Mu01 | Polyclonal Antibody to Von Willebrand Factor A Domain Containing Protein 2 (vWA2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV445Mu01 | CLIA Kit for Von Willebrand Factor A Domain Containing Protein 2 (vWA2) | CLIA assay for Antigen Detection |
| ELV445Mu01 | ELISA Kit for Von Willebrand Factor A Domain Containing Protein 2 (vWA2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV445Ra01 | Recombinant Von Willebrand Factor A Domain Containing Protein 2 (vWA2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV445Ra01 | Monoclonal Antibody to Von Willebrand Factor A Domain Containing Protein 2 (vWA2) | WB; IHC; ICC; IP. |
| PAV445Ra01 | Polyclonal Antibody to Von Willebrand Factor A Domain Containing Protein 2 (vWA2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV445Ra01 | CLIA Kit for Von Willebrand Factor A Domain Containing Protein 2 (vWA2) | CLIA assay for Antigen Detection |
| ELV445Ra01 | ELISA Kit for Von Willebrand Factor A Domain Containing Protein 2 (vWA2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV445Ca01 | Recombinant Von Willebrand Factor A Domain Containing Protein 2 (vWA2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV445Ca01 | Monoclonal Antibody to Von Willebrand Factor A Domain Containing Protein 2 (vWA2) | WB; IHC; ICC; IP. |
| PAV445Ca01 | Polyclonal Antibody to Von Willebrand Factor A Domain Containing Protein 2 (vWA2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV445Ca01 | CLIA Kit for Von Willebrand Factor A Domain Containing Protein 2 (vWA2) | CLIA assay for Antigen Detection |
| ELV445Ca01 | ELISA Kit for Von Willebrand Factor A Domain Containing Protein 2 (vWA2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV445Po01 | Recombinant Von Willebrand Factor A Domain Containing Protein 2 (vWA2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV445Po01 | Monoclonal Antibody to Von Willebrand Factor A Domain Containing Protein 2 (vWA2) | WB; IHC; ICC; IP. |
| PAV445Po01 | Polyclonal Antibody to Von Willebrand Factor A Domain Containing Protein 2 (vWA2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV445Po01 | CLIA Kit for Von Willebrand Factor A Domain Containing Protein 2 (vWA2) | CLIA assay for Antigen Detection |
| ELV445Po01 | ELISA Kit for Von Willebrand Factor A Domain Containing Protein 2 (vWA2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV445Bo01 | Recombinant Von Willebrand Factor A Domain Containing Protein 2 (vWA2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV445Bo01 | Monoclonal Antibody to Von Willebrand Factor A Domain Containing Protein 2 (vWA2) | WB; IHC; ICC; IP. |
| PAV445Bo01 | Polyclonal Antibody to Von Willebrand Factor A Domain Containing Protein 2 (vWA2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV445Bo01 | CLIA Kit for Von Willebrand Factor A Domain Containing Protein 2 (vWA2) | CLIA assay for Antigen Detection |
| ELV445Bo01 | ELISA Kit for Von Willebrand Factor A Domain Containing Protein 2 (vWA2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV445Rb01 | Recombinant Von Willebrand Factor A Domain Containing Protein 2 (vWA2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV445Rb01 | Monoclonal Antibody to Von Willebrand Factor A Domain Containing Protein 2 (vWA2) | WB; IHC; ICC; IP. |
| PAV445Rb01 | Polyclonal Antibody to Von Willebrand Factor A Domain Containing Protein 2 (vWA2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV445Rb01 | CLIA Kit for Von Willebrand Factor A Domain Containing Protein 2 (vWA2) | CLIA assay for Antigen Detection |
| ELV445Rb01 | ELISA Kit for Von Willebrand Factor A Domain Containing Protein 2 (vWA2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV445Mo01 | Recombinant Von Willebrand Factor A Domain Containing Protein 2 (vWA2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV445Mo01 | Monoclonal Antibody to Von Willebrand Factor A Domain Containing Protein 2 (vWA2) | WB; IHC; ICC; IP. |
| PAV445Mo01 | Polyclonal Antibody to Von Willebrand Factor A Domain Containing Protein 2 (vWA2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV445Mo01 | CLIA Kit for Von Willebrand Factor A Domain Containing Protein 2 (vWA2) | CLIA assay for Antigen Detection |
| ELV445Mo01 | ELISA Kit for Von Willebrand Factor A Domain Containing Protein 2 (vWA2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"Identification and characterization of AMACO, a new member of the von Willebrand factor A-like domain protein superfamily with a regulated expression in the kidney."
J. Biol. Chem. 278:50240-50249(2003) [PubMed] [Europe PMC] [Abstract]
"Colon cancer secreted protein-2 (CCSP-2), a novel candidate serological marker of colon neoplasia."
Oncogene 24:724-731(2005) [PubMed] [Europe PMC] [Abstract]
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Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
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Nature 429:375-381(2004) [PubMed] [Europe PMC] [Abstract]
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Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
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Science 314:268-274(2006) [PubMed] [Europe PMC] [Abstract]