Leukocyte Immunoglobulin Like Receptor Subfamily B, Member 1 (LILRB1)
CD85j; LILR-B1; ILT2; LIR1; MIR7; CD85 antigen-like family member J; Immunoglobulin-like transcript 2; Monocyte/macrophage immunoglobulin-like receptor 7
Leukocyte immunoglobulin-like receptor subfamily B member 1is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV439Hu01 | Recombinant Leukocyte Immunoglobulin Like Receptor Subfamily B, Member 1 (LILRB1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV439Hu01 | Monoclonal Antibody to Leukocyte Immunoglobulin Like Receptor Subfamily B, Member 1 (LILRB1) | WB; IHC; ICC; IP. |
| PAV439Hu01 | Polyclonal Antibody to Leukocyte Immunoglobulin Like Receptor Subfamily B, Member 1 (LILRB1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV439Hu01 | CLIA Kit for Leukocyte Immunoglobulin Like Receptor Subfamily B, Member 1 (LILRB1) | CLIA assay for Antigen Detection |
| ELV439Hu01 | ELISA Kit for Leukocyte Immunoglobulin Like Receptor Subfamily B, Member 1 (LILRB1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV439Mu01 | Recombinant Leukocyte Immunoglobulin Like Receptor Subfamily B, Member 1 (LILRB1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV439Mu01 | Monoclonal Antibody to Leukocyte Immunoglobulin Like Receptor Subfamily B, Member 1 (LILRB1) | WB; IHC; ICC; IP. |
| PAV439Mu01 | Polyclonal Antibody to Leukocyte Immunoglobulin Like Receptor Subfamily B, Member 1 (LILRB1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV439Mu01 | CLIA Kit for Leukocyte Immunoglobulin Like Receptor Subfamily B, Member 1 (LILRB1) | CLIA assay for Antigen Detection |
| ELV439Mu01 | ELISA Kit for Leukocyte Immunoglobulin Like Receptor Subfamily B, Member 1 (LILRB1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV439Ra01 | Recombinant Leukocyte Immunoglobulin Like Receptor Subfamily B, Member 1 (LILRB1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV439Ra01 | Monoclonal Antibody to Leukocyte Immunoglobulin Like Receptor Subfamily B, Member 1 (LILRB1) | WB; IHC; ICC; IP. |
| PAV439Ra01 | Polyclonal Antibody to Leukocyte Immunoglobulin Like Receptor Subfamily B, Member 1 (LILRB1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV439Ra01 | CLIA Kit for Leukocyte Immunoglobulin Like Receptor Subfamily B, Member 1 (LILRB1) | CLIA assay for Antigen Detection |
| ELV439Ra01 | ELISA Kit for Leukocyte Immunoglobulin Like Receptor Subfamily B, Member 1 (LILRB1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV439Ca01 | Recombinant Leukocyte Immunoglobulin Like Receptor Subfamily B, Member 1 (LILRB1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV439Ca01 | Monoclonal Antibody to Leukocyte Immunoglobulin Like Receptor Subfamily B, Member 1 (LILRB1) | WB; IHC; ICC; IP. |
| PAV439Ca01 | Polyclonal Antibody to Leukocyte Immunoglobulin Like Receptor Subfamily B, Member 1 (LILRB1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV439Ca01 | CLIA Kit for Leukocyte Immunoglobulin Like Receptor Subfamily B, Member 1 (LILRB1) | CLIA assay for Antigen Detection |
| ELV439Ca01 | ELISA Kit for Leukocyte Immunoglobulin Like Receptor Subfamily B, Member 1 (LILRB1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV439Po01 | Recombinant Leukocyte Immunoglobulin Like Receptor Subfamily B, Member 1 (LILRB1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV439Po01 | Monoclonal Antibody to Leukocyte Immunoglobulin Like Receptor Subfamily B, Member 1 (LILRB1) | WB; IHC; ICC; IP. |
| PAV439Po01 | Polyclonal Antibody to Leukocyte Immunoglobulin Like Receptor Subfamily B, Member 1 (LILRB1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV439Po01 | CLIA Kit for Leukocyte Immunoglobulin Like Receptor Subfamily B, Member 1 (LILRB1) | CLIA assay for Antigen Detection |
| ELV439Po01 | ELISA Kit for Leukocyte Immunoglobulin Like Receptor Subfamily B, Member 1 (LILRB1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV439Bo01 | Recombinant Leukocyte Immunoglobulin Like Receptor Subfamily B, Member 1 (LILRB1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV439Bo01 | Monoclonal Antibody to Leukocyte Immunoglobulin Like Receptor Subfamily B, Member 1 (LILRB1) | WB; IHC; ICC; IP. |
| PAV439Bo01 | Polyclonal Antibody to Leukocyte Immunoglobulin Like Receptor Subfamily B, Member 1 (LILRB1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV439Bo01 | CLIA Kit for Leukocyte Immunoglobulin Like Receptor Subfamily B, Member 1 (LILRB1) | CLIA assay for Antigen Detection |
| ELV439Bo01 | ELISA Kit for Leukocyte Immunoglobulin Like Receptor Subfamily B, Member 1 (LILRB1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV439Rb01 | Recombinant Leukocyte Immunoglobulin Like Receptor Subfamily B, Member 1 (LILRB1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV439Rb01 | Monoclonal Antibody to Leukocyte Immunoglobulin Like Receptor Subfamily B, Member 1 (LILRB1) | WB; IHC; ICC; IP. |
| PAV439Rb01 | Polyclonal Antibody to Leukocyte Immunoglobulin Like Receptor Subfamily B, Member 1 (LILRB1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV439Rb01 | CLIA Kit for Leukocyte Immunoglobulin Like Receptor Subfamily B, Member 1 (LILRB1) | CLIA assay for Antigen Detection |
| ELV439Rb01 | ELISA Kit for Leukocyte Immunoglobulin Like Receptor Subfamily B, Member 1 (LILRB1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV439Mo01 | Recombinant Leukocyte Immunoglobulin Like Receptor Subfamily B, Member 1 (LILRB1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV439Mo01 | Monoclonal Antibody to Leukocyte Immunoglobulin Like Receptor Subfamily B, Member 1 (LILRB1) | WB; IHC; ICC; IP. |
| PAV439Mo01 | Polyclonal Antibody to Leukocyte Immunoglobulin Like Receptor Subfamily B, Member 1 (LILRB1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV439Mo01 | CLIA Kit for Leukocyte Immunoglobulin Like Receptor Subfamily B, Member 1 (LILRB1) | CLIA assay for Antigen Detection |
| ELV439Mo01 | ELISA Kit for Leukocyte Immunoglobulin Like Receptor Subfamily B, Member 1 (LILRB1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
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Curr. Biol. 7:615-618(1997) [PubMed] [Europe PMC] [Abstract]
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Immunity 7:273-282(1997) [PubMed] [Europe PMC] [Abstract]
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Immunogenetics 51:659-669(2000) [PubMed] [Europe PMC] [Abstract]
"Alternative mRNA splicing creates transcripts encoding soluble proteins from most LILR genes."
Eur. J. Immunol. 39:3195-3206(2009) [PubMed] [Europe PMC] [Abstract]
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Hum. Immunol. 71:942-949(2010) [PubMed] [Europe PMC] [Abstract]
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Nature 428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
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Immunity 11:603-613(1999) [PubMed] [Europe PMC] [Abstract]
"Mutational analysis of immunoreceptor tyrosine-based inhibition motifs of the Ig-like transcript 2 (CD85j) leukocyte receptor."
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Immunity 13:727-736(2000) [PubMed] [Europe PMC] [Abstract]