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Adenylate Cyclase 2, Brain (ADCY2)

HBAC2; ATP pyrophosphate-lyase 2; Adenylate cyclase type II

Adenylate cyclase type 2 is a member of the family of adenylate cyclases, which are membrane-associated enzymes that catalyze the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). This enzyme is insensitive to Ca(2+)/calmodulin, and is stimulated by the G protein beta and gamma subunit complex.

The amino acid sequence of ADCY2 displayed significant homology with ADCY8 in the highly conserved adenylyl cyclase domain (250 amino acids) found in the 3-prime cytoplasmic portion of all mammalian adenylyl cyclases. However, outside this domain, the homology was extremely low.Semiquantitative RT-PCR detected ADCY2 in all tissues examined except peripheral blood leukocytes. Highest expression was detected in brain, skeletal muscle, and testis.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins V431Hu01 Recombinant Adenylate Cyclase 2, Brain (ADCY2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Adenylate Cyclase 2, Brain (ADCY2) Bioactivity
Antibodies MV431Hu22 Monoclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) WB; IHC; ICC; IP.
PV431Hu01 Polyclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) Flow Cytometry;ICC/IF
Assay Kits KEV431Hu ELISA Kit for Adenylate Cyclase 2, Brain (ADCY2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Adenylate Cyclase 2, Brain (ADCY2) CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Adenylate Cyclase 2, Brain (ADCY2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Adenylate Cyclase 2, Brain (ADCY2) Bioactivity
Antibodies NONE Monoclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Adenylate Cyclase 2, Brain (ADCY2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Adenylate Cyclase 2, Brain (ADCY2) CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Adenylate Cyclase 2, Brain (ADCY2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Adenylate Cyclase 2, Brain (ADCY2) Bioactivity
Antibodies NONE Monoclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Adenylate Cyclase 2, Brain (ADCY2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Adenylate Cyclase 2, Brain (ADCY2) CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Adenylate Cyclase 2, Brain (ADCY2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Adenylate Cyclase 2, Brain (ADCY2) Bioactivity
Antibodies NONE Monoclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Adenylate Cyclase 2, Brain (ADCY2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Adenylate Cyclase 2, Brain (ADCY2) CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Adenylate Cyclase 2, Brain (ADCY2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Adenylate Cyclase 2, Brain (ADCY2) Bioactivity
Antibodies NONE Monoclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Adenylate Cyclase 2, Brain (ADCY2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Adenylate Cyclase 2, Brain (ADCY2) CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Adenylate Cyclase 2, Brain (ADCY2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Adenylate Cyclase 2, Brain (ADCY2) Bioactivity
Antibodies NONE Monoclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Adenylate Cyclase 2, Brain (ADCY2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Adenylate Cyclase 2, Brain (ADCY2) CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Adenylate Cyclase 2, Brain (ADCY2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Adenylate Cyclase 2, Brain (ADCY2) Bioactivity
Antibodies NONE Monoclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Adenylate Cyclase 2, Brain (ADCY2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Adenylate Cyclase 2, Brain (ADCY2) CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Adenylate Cyclase 2, Brain (ADCY2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Adenylate Cyclase 2, Brain (ADCY2) Bioactivity
Antibodies NONE Monoclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Adenylate Cyclase 2, Brain (ADCY2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Adenylate Cyclase 2, Brain (ADCY2) CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Adenylate Cyclase 2, Brain (ADCY2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Adenylate Cyclase 2, Brain (ADCY2) Bioactivity
Antibodies NONE Monoclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Adenylate Cyclase 2, Brain (ADCY2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Adenylate Cyclase 2, Brain (ADCY2) CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Adenylate Cyclase 2, Brain (ADCY2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Adenylate Cyclase 2, Brain (ADCY2) Bioactivity
Antibodies NONE Monoclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Adenylate Cyclase 2, Brain (ADCY2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Adenylate Cyclase 2, Brain (ADCY2) CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Adenylate Cyclase 2, Brain (ADCY2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Adenylate Cyclase 2, Brain (ADCY2) Bioactivity
Antibodies NONE Monoclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Adenylate Cyclase 2, Brain (ADCY2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Adenylate Cyclase 2, Brain (ADCY2) CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Adenylate Cyclase 2, Brain (ADCY2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Adenylate Cyclase 2, Brain (ADCY2) Bioactivity
Antibodies NONE Monoclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Adenylate Cyclase 2, Brain (ADCY2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Adenylate Cyclase 2, Brain (ADCY2) CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Adenylate Cyclase 2, Brain (ADCY2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Adenylate Cyclase 2, Brain (ADCY2) Bioactivity
Antibodies NONE Monoclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Adenylate Cyclase 2, Brain (ADCY2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Adenylate Cyclase 2, Brain (ADCY2) CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Adenylate Cyclase 2, Brain (ADCY2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Adenylate Cyclase 2, Brain (ADCY2) Bioactivity
Antibodies NONE Monoclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Adenylate Cyclase 2, Brain (ADCY2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Adenylate Cyclase 2, Brain (ADCY2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Adenylate Cyclase 2, Brain (ADCY2) CLIA assay for Antigen Detection

Reference

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

"The DNA sequence and comparative analysis of human chromosome 5."
Nature 431:268-274(2004) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."
DNA Res. 6:197-205(1999) [PubMed] [Europe PMC] [Abstract]

"Different chromosomal localization of two adenylyl cyclase genes expressed in human brain."
Hum. Genet. 90:126-130(1992) [PubMed] [Europe PMC] [Abstract]

"A novel adenylyl cyclase sequence cloned from the human erythroleukemia cell line."
Biochem. Biophys. Res. Commun. 192:311-318(1993) [PubMed] [Europe PMC] [Abstract]

"Raf kinase activation of adenylyl cyclases: isoform-selective regulation."
Mol. Pharmacol. 66:921-928(2004) [PubMed] [Europe PMC] [Abstract]