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Lipopolysaccharide Binding Protein (LBP)

LPS-Binding Protein

LPS-binding protein (LBP) is serum factor known to regulate the endotoxin-induced cellular immune response. Sepsis is a morbid condition induced by a toxin, the introduction or accumulation of which is most commonly caused by infection or trauma. Sepsis-inducing toxins have been found associated with pathogenic bacteria, viruses, plants and venoms.

Among the well described bacterial toxins are the endotoxins or lipopolysaccharides (LPS) of the gram-negative bacteria. Upon introduction of LPS into the blood it binds to lipopolysaccharide binding protein (LBP). LBP recognizes the lipid A region of LPS and forms high affinity complexes with both rough and smooth form LPS. During the acute phase, LBP is synthesized by hepatocytes, and reaches very high concentrations in serum.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins V428Hu01 Recombinant Lipopolysaccharide Binding Protein (LBP) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Lipopolysaccharide Binding Protein (LBP) Bioactivity
Antibodies MV428Hu22 Monoclonal Antibody to Lipopolysaccharide Binding Protein (LBP) WB; IHC; ICC; IP.
PV428Hu01 Polyclonal Antibody to Lipopolysaccharide Binding Protein (LBP) WB; IHC; ICC; IF.
LV428Hu71 Biotin Linked-Polyclonal Antibody to Lipopolysaccharide Binding Protein (LBP) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Lipopolysaccharide Binding Protein (LBP) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Lipopolysaccharide Binding Protein (LBP) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Lipopolysaccharide Binding Protein (LBP) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Lipopolysaccharide Binding Protein (LBP) Flow Cytometry;ICC/IF
Assay Kits KEV428Hu ELISA Kit for Lipopolysaccharide Binding Protein (LBP) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Lipopolysaccharide Binding Protein (LBP) CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins V428Mu01 Recombinant Lipopolysaccharide Binding Protein (LBP) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Lipopolysaccharide Binding Protein (LBP) Bioactivity
Antibodies NONE Monoclonal Antibody to Lipopolysaccharide Binding Protein (LBP) WB; IHC; ICC; IP.
PV428Mu01 Polyclonal Antibody to Lipopolysaccharide Binding Protein (LBP) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Lipopolysaccharide Binding Protein (LBP) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Lipopolysaccharide Binding Protein (LBP) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Lipopolysaccharide Binding Protein (LBP) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Lipopolysaccharide Binding Protein (LBP) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Lipopolysaccharide Binding Protein (LBP) Flow Cytometry;ICC/IF
Assay Kits KEV428Mu ELISA Kit for Lipopolysaccharide Binding Protein (LBP) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Lipopolysaccharide Binding Protein (LBP) CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins V428Ra01 Recombinant Lipopolysaccharide Binding Protein (LBP) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Lipopolysaccharide Binding Protein (LBP) Bioactivity
Antibodies MV428Ra21 Monoclonal Antibody to Lipopolysaccharide Binding Protein (LBP) WB; IHC; ICC; IP.
PV428Ra01 Polyclonal Antibody to Lipopolysaccharide Binding Protein (LBP) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Lipopolysaccharide Binding Protein (LBP) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Lipopolysaccharide Binding Protein (LBP) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Lipopolysaccharide Binding Protein (LBP) Simple Western; WB
LV428Ra41 PE Linked-Polyclonal Antibody to Lipopolysaccharide Binding Protein (LBP) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Lipopolysaccharide Binding Protein (LBP) Flow Cytometry;ICC/IF
Assay Kits KEV428Ra ELISA Kit for Lipopolysaccharide Binding Protein (LBP) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Lipopolysaccharide Binding Protein (LBP) CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Lipopolysaccharide Binding Protein (LBP) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Lipopolysaccharide Binding Protein (LBP) Bioactivity
Antibodies NONE Monoclonal Antibody to Lipopolysaccharide Binding Protein (LBP) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Lipopolysaccharide Binding Protein (LBP) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Lipopolysaccharide Binding Protein (LBP) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Lipopolysaccharide Binding Protein (LBP) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Lipopolysaccharide Binding Protein (LBP) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Lipopolysaccharide Binding Protein (LBP) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Lipopolysaccharide Binding Protein (LBP) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Lipopolysaccharide Binding Protein (LBP) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Lipopolysaccharide Binding Protein (LBP) CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins V428Po01 Recombinant Lipopolysaccharide Binding Protein (LBP) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Lipopolysaccharide Binding Protein (LBP) Bioactivity
Antibodies MV428Po21 Monoclonal Antibody to Lipopolysaccharide Binding Protein (LBP) WB; IHC; ICC; IP.
PV428Po01 Polyclonal Antibody to Lipopolysaccharide Binding Protein (LBP) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Lipopolysaccharide Binding Protein (LBP) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Lipopolysaccharide Binding Protein (LBP) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Lipopolysaccharide Binding Protein (LBP) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Lipopolysaccharide Binding Protein (LBP) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Lipopolysaccharide Binding Protein (LBP) Flow Cytometry;ICC/IF
Assay Kits KEV428Po ELISA Kit for Lipopolysaccharide Binding Protein (LBP) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Lipopolysaccharide Binding Protein (LBP) CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins V428Bo01 Recombinant Lipopolysaccharide Binding Protein (LBP) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Lipopolysaccharide Binding Protein (LBP) Bioactivity
Antibodies MV428Bo21 Monoclonal Antibody to Lipopolysaccharide Binding Protein (LBP) WB; IHC; ICC; IP.
PV428Bo01 Polyclonal Antibody to Lipopolysaccharide Binding Protein (LBP) WB; IHC; ICC; IF.
LV428Bo71 Biotin Linked-Polyclonal Antibody to Lipopolysaccharide Binding Protein (LBP) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Lipopolysaccharide Binding Protein (LBP) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Lipopolysaccharide Binding Protein (LBP) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Lipopolysaccharide Binding Protein (LBP) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Lipopolysaccharide Binding Protein (LBP) Flow Cytometry;ICC/IF
Assay Kits KEV428Bo ELISA Kit for Lipopolysaccharide Binding Protein (LBP) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Lipopolysaccharide Binding Protein (LBP) CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Lipopolysaccharide Binding Protein (LBP) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Lipopolysaccharide Binding Protein (LBP) Bioactivity
Antibodies NONE Monoclonal Antibody to Lipopolysaccharide Binding Protein (LBP) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Lipopolysaccharide Binding Protein (LBP) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Lipopolysaccharide Binding Protein (LBP) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Lipopolysaccharide Binding Protein (LBP) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Lipopolysaccharide Binding Protein (LBP) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Lipopolysaccharide Binding Protein (LBP) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Lipopolysaccharide Binding Protein (LBP) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Lipopolysaccharide Binding Protein (LBP) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Lipopolysaccharide Binding Protein (LBP) CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Lipopolysaccharide Binding Protein (LBP) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Lipopolysaccharide Binding Protein (LBP) Bioactivity
Antibodies NONE Monoclonal Antibody to Lipopolysaccharide Binding Protein (LBP) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Lipopolysaccharide Binding Protein (LBP) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Lipopolysaccharide Binding Protein (LBP) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Lipopolysaccharide Binding Protein (LBP) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Lipopolysaccharide Binding Protein (LBP) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Lipopolysaccharide Binding Protein (LBP) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Lipopolysaccharide Binding Protein (LBP) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Lipopolysaccharide Binding Protein (LBP) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Lipopolysaccharide Binding Protein (LBP) CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Lipopolysaccharide Binding Protein (LBP) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Lipopolysaccharide Binding Protein (LBP) Bioactivity
Antibodies NONE Monoclonal Antibody to Lipopolysaccharide Binding Protein (LBP) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Lipopolysaccharide Binding Protein (LBP) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Lipopolysaccharide Binding Protein (LBP) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Lipopolysaccharide Binding Protein (LBP) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Lipopolysaccharide Binding Protein (LBP) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Lipopolysaccharide Binding Protein (LBP) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Lipopolysaccharide Binding Protein (LBP) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Lipopolysaccharide Binding Protein (LBP) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Lipopolysaccharide Binding Protein (LBP) CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins V428Rb01 Recombinant Lipopolysaccharide Binding Protein (LBP) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Lipopolysaccharide Binding Protein (LBP) Bioactivity
Antibodies NONE Monoclonal Antibody to Lipopolysaccharide Binding Protein (LBP) WB; IHC; ICC; IP.
PV428Rb51 Polyclonal Antibody to Lipopolysaccharide Binding Protein (LBP) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Lipopolysaccharide Binding Protein (LBP) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Lipopolysaccharide Binding Protein (LBP) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Lipopolysaccharide Binding Protein (LBP) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Lipopolysaccharide Binding Protein (LBP) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Lipopolysaccharide Binding Protein (LBP) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Lipopolysaccharide Binding Protein (LBP) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Lipopolysaccharide Binding Protein (LBP) CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Lipopolysaccharide Binding Protein (LBP) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Lipopolysaccharide Binding Protein (LBP) Bioactivity
Antibodies NONE Monoclonal Antibody to Lipopolysaccharide Binding Protein (LBP) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Lipopolysaccharide Binding Protein (LBP) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Lipopolysaccharide Binding Protein (LBP) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Lipopolysaccharide Binding Protein (LBP) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Lipopolysaccharide Binding Protein (LBP) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Lipopolysaccharide Binding Protein (LBP) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Lipopolysaccharide Binding Protein (LBP) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Lipopolysaccharide Binding Protein (LBP) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Lipopolysaccharide Binding Protein (LBP) CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Lipopolysaccharide Binding Protein (LBP) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Lipopolysaccharide Binding Protein (LBP) Bioactivity
Antibodies NONE Monoclonal Antibody to Lipopolysaccharide Binding Protein (LBP) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Lipopolysaccharide Binding Protein (LBP) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Lipopolysaccharide Binding Protein (LBP) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Lipopolysaccharide Binding Protein (LBP) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Lipopolysaccharide Binding Protein (LBP) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Lipopolysaccharide Binding Protein (LBP) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Lipopolysaccharide Binding Protein (LBP) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Lipopolysaccharide Binding Protein (LBP) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Lipopolysaccharide Binding Protein (LBP) CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Lipopolysaccharide Binding Protein (LBP) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Lipopolysaccharide Binding Protein (LBP) Bioactivity
Antibodies NONE Monoclonal Antibody to Lipopolysaccharide Binding Protein (LBP) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Lipopolysaccharide Binding Protein (LBP) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Lipopolysaccharide Binding Protein (LBP) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Lipopolysaccharide Binding Protein (LBP) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Lipopolysaccharide Binding Protein (LBP) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Lipopolysaccharide Binding Protein (LBP) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Lipopolysaccharide Binding Protein (LBP) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Lipopolysaccharide Binding Protein (LBP) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Lipopolysaccharide Binding Protein (LBP) CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Lipopolysaccharide Binding Protein (LBP) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Lipopolysaccharide Binding Protein (LBP) Bioactivity
Antibodies NONE Monoclonal Antibody to Lipopolysaccharide Binding Protein (LBP) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Lipopolysaccharide Binding Protein (LBP) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Lipopolysaccharide Binding Protein (LBP) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Lipopolysaccharide Binding Protein (LBP) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Lipopolysaccharide Binding Protein (LBP) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Lipopolysaccharide Binding Protein (LBP) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Lipopolysaccharide Binding Protein (LBP) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Lipopolysaccharide Binding Protein (LBP) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Lipopolysaccharide Binding Protein (LBP) CLIA assay for Antigen Detection

Reference

"Structure and function of lipopolysaccharide binding protein."
Science 249:1429-1431(1990) [PubMed] [Europe PMC] [Abstract]

"Bactericidal/permeability-increasing protein and lipopolysaccharide (LPS)-binding protein. LPS binding properties and effects on LPS-mediated cell activation."
J. Biol. Chem. 269:17411-17416(1994) [PubMed] [Europe PMC] [Abstract]

"The genomic organization of the genes for human lipopolysaccharide binding protein (LBP) and bactericidal permeability increasing protein (BPI) is highly conserved."
Biochem. Biophys. Res. Commun. 236:427-430(1997) [PubMed] [Europe PMC] [Abstract]

"Similar organization of the lipopolysaccharide-binding protein (LBP) and phospholipid transfer protein (PLTP) genes suggests a common gene family of lipid-binding proteins."
Genomics 46:416-425(1997) [PubMed] [Europe PMC] [Abstract]

"Cloning and sequencing of human lipopolysaccharide-binding protein gene."
Sheng Wu Hua Xue Yu Sheng Wu Wu Li Jin Zhan 25:469-471(1998)

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

"The DNA sequence and comparative analysis of human chromosome 20."
Nature 414:865-871(2001) [PubMed] [Europe PMC] [Abstract]

"Structural biology of the LPS recognition."
Int. J. Med. Microbiol. 297:353-363(2007) [PubMed] [Europe PMC] [Abstract]

"Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."
J. Proteome Res. 8:651-661(2009) [PubMed] [Europe PMC] [Abstract]

"The crystal structure of lipopolysaccharide binding protein reveals the location of a frequent mutation that impairs innate immunity."
Immunity 39:647-660(2013) [PubMed] [Europe PMC] [Abstract]