Early Growth Response Protein 2 (EGR2)
CMT1D; CMT4E; KROX20; Krox-20 Homolog,Drosophil; E3 SUMO-protein ligase EGR2; Zinc finger protein Krox-20
The early growth response protein 2 is a transcription factor with three tandem C2H2-type zinc fingers. Mutations in this gene are associated with the autosomal dominant Charcot-Marie-Tooth disease, type 1. Using microarray expression profiling, Nagarajan et al. identified 98 known genes that were induced by Egr2 in Schwann cells. The putative Egr2 target genes included myelin proteins and enzymes required for synthesis of normal myelin lipids. Using RT-PCR to monitor Schwann cell gene expression, Nagarajan et al. confirmed that Egr2 is sufficient for induction of target genes including MPZ , PMP22 , MBP , MAG , CX32 , and periaxin. Using EGR2 DNA-binding domain mutants, Nagarajan et al. demonstrated a dominant-negative inhibition of wildtype Egr2-mediated induction of essential myelin genes.
Organism species: Homo sapiens (Human)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | V383Hu01 | Recombinant Early Growth Response Protein 2 (EGR2) | Positive Control; Immunogen; SDS-PAGE; WB. |
NONE | Native Early Growth Response Protein 2 (EGR2) | Bioactivity | |
Antibodies | NONE | Monoclonal Antibody to Early Growth Response Protein 2 (EGR2) | WB; IHC; ICC; IP. |
PV383Hu01 | Polyclonal Antibody to Early Growth Response Protein 2 (EGR2) | WB; IHC; ICC; IF. | |
NONE | Biotin Linked-Polyclonal Antibody to Early Growth Response Protein 2 (EGR2) | ELISA(Det);IC; IH; IH(P); WB | |
NONE | APC Linked-Polyclonal Antibody to Early Growth Response Protein 2 (EGR2) | IHC, WB | |
NONE | HRP Linked-Polyclonal Antibody to Early Growth Response Protein 2 (EGR2) | Simple Western; WB | |
NONE | PE Linked-Polyclonal Antibody to Early Growth Response Protein 2 (EGR2) | Flow Cytometry | |
NONE | FITC Linked-Polyclonal Antibody to Early Growth Response Protein 2 (EGR2) | Flow Cytometry;ICC/IF | |
Assay Kits | NONE | ELISA Kit for Early Growth Response Protein 2 (EGR2) | Enzyme-linked immunosorbent assay for Antigen Detection |
NONE | CLIA kit for Early Growth Response Protein 2 (EGR2) | CLIA assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | V383Mu01 | Recombinant Early Growth Response Protein 2 (EGR2) | Positive Control; Immunogen; SDS-PAGE; WB. |
NONE | Native Early Growth Response Protein 2 (EGR2) | Bioactivity | |
Antibodies | NONE | Monoclonal Antibody to Early Growth Response Protein 2 (EGR2) | WB; IHC; ICC; IP. |
PV383Mu01 | Polyclonal Antibody to Early Growth Response Protein 2 (EGR2) | WB; IHC; ICC; IF. | |
NONE | Biotin Linked-Polyclonal Antibody to Early Growth Response Protein 2 (EGR2) | ELISA(Det);IC; IH; IH(P); WB | |
NONE | APC Linked-Polyclonal Antibody to Early Growth Response Protein 2 (EGR2) | IHC, WB | |
NONE | HRP Linked-Polyclonal Antibody to Early Growth Response Protein 2 (EGR2) | Simple Western; WB | |
NONE | PE Linked-Polyclonal Antibody to Early Growth Response Protein 2 (EGR2) | Flow Cytometry | |
NONE | FITC Linked-Polyclonal Antibody to Early Growth Response Protein 2 (EGR2) | Flow Cytometry;ICC/IF | |
Assay Kits | NONE | ELISA Kit for Early Growth Response Protein 2 (EGR2) | Enzyme-linked immunosorbent assay for Antigen Detection |
NONE | CLIA kit for Early Growth Response Protein 2 (EGR2) | CLIA assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | NONE | Recombinant Early Growth Response Protein 2 (EGR2) | Positive Control; Immunogen; SDS-PAGE; WB. |
NONE | Native Early Growth Response Protein 2 (EGR2) | Bioactivity | |
Antibodies | NONE | Monoclonal Antibody to Early Growth Response Protein 2 (EGR2) | WB; IHC; ICC; IP. |
NONE | Polyclonal Antibody to Early Growth Response Protein 2 (EGR2) | WB; IHC; ICC; IF. | |
NONE | Biotin Linked-Polyclonal Antibody to Early Growth Response Protein 2 (EGR2) | ELISA(Det);IC; IH; IH(P); WB | |
NONE | APC Linked-Polyclonal Antibody to Early Growth Response Protein 2 (EGR2) | IHC, WB | |
NONE | HRP Linked-Polyclonal Antibody to Early Growth Response Protein 2 (EGR2) | Simple Western; WB | |
NONE | PE Linked-Polyclonal Antibody to Early Growth Response Protein 2 (EGR2) | Flow Cytometry | |
NONE | FITC Linked-Polyclonal Antibody to Early Growth Response Protein 2 (EGR2) | Flow Cytometry;ICC/IF | |
Assay Kits | NONE | ELISA Kit for Early Growth Response Protein 2 (EGR2) | Enzyme-linked immunosorbent assay for Antigen Detection |
NONE | CLIA kit for Early Growth Response Protein 2 (EGR2) | CLIA assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | NONE | Recombinant Early Growth Response Protein 2 (EGR2) | Positive Control; Immunogen; SDS-PAGE; WB. |
NONE | Native Early Growth Response Protein 2 (EGR2) | Bioactivity | |
Antibodies | NONE | Monoclonal Antibody to Early Growth Response Protein 2 (EGR2) | WB; IHC; ICC; IP. |
NONE | Polyclonal Antibody to Early Growth Response Protein 2 (EGR2) | WB; IHC; ICC; IF. | |
NONE | Biotin Linked-Polyclonal Antibody to Early Growth Response Protein 2 (EGR2) | ELISA(Det);IC; IH; IH(P); WB | |
NONE | APC Linked-Polyclonal Antibody to Early Growth Response Protein 2 (EGR2) | IHC, WB | |
NONE | HRP Linked-Polyclonal Antibody to Early Growth Response Protein 2 (EGR2) | Simple Western; WB | |
NONE | PE Linked-Polyclonal Antibody to Early Growth Response Protein 2 (EGR2) | Flow Cytometry | |
NONE | FITC Linked-Polyclonal Antibody to Early Growth Response Protein 2 (EGR2) | Flow Cytometry;ICC/IF | |
Assay Kits | NONE | ELISA Kit for Early Growth Response Protein 2 (EGR2) | Enzyme-linked immunosorbent assay for Antigen Detection |
NONE | CLIA kit for Early Growth Response Protein 2 (EGR2) | CLIA assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | NONE | Recombinant Early Growth Response Protein 2 (EGR2) | Positive Control; Immunogen; SDS-PAGE; WB. |
NONE | Native Early Growth Response Protein 2 (EGR2) | Bioactivity | |
Antibodies | NONE | Monoclonal Antibody to Early Growth Response Protein 2 (EGR2) | WB; IHC; ICC; IP. |
NONE | Polyclonal Antibody to Early Growth Response Protein 2 (EGR2) | WB; IHC; ICC; IF. | |
NONE | Biotin Linked-Polyclonal Antibody to Early Growth Response Protein 2 (EGR2) | ELISA(Det);IC; IH; IH(P); WB | |
NONE | APC Linked-Polyclonal Antibody to Early Growth Response Protein 2 (EGR2) | IHC, WB | |
NONE | HRP Linked-Polyclonal Antibody to Early Growth Response Protein 2 (EGR2) | Simple Western; WB | |
NONE | PE Linked-Polyclonal Antibody to Early Growth Response Protein 2 (EGR2) | Flow Cytometry | |
NONE | FITC Linked-Polyclonal Antibody to Early Growth Response Protein 2 (EGR2) | Flow Cytometry;ICC/IF | |
Assay Kits | NONE | ELISA Kit for Early Growth Response Protein 2 (EGR2) | Enzyme-linked immunosorbent assay for Antigen Detection |
NONE | CLIA kit for Early Growth Response Protein 2 (EGR2) | CLIA assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | NONE | Recombinant Early Growth Response Protein 2 (EGR2) | Positive Control; Immunogen; SDS-PAGE; WB. |
NONE | Native Early Growth Response Protein 2 (EGR2) | Bioactivity | |
Antibodies | NONE | Monoclonal Antibody to Early Growth Response Protein 2 (EGR2) | WB; IHC; ICC; IP. |
NONE | Polyclonal Antibody to Early Growth Response Protein 2 (EGR2) | WB; IHC; ICC; IF. | |
NONE | Biotin Linked-Polyclonal Antibody to Early Growth Response Protein 2 (EGR2) | ELISA(Det);IC; IH; IH(P); WB | |
NONE | APC Linked-Polyclonal Antibody to Early Growth Response Protein 2 (EGR2) | IHC, WB | |
NONE | HRP Linked-Polyclonal Antibody to Early Growth Response Protein 2 (EGR2) | Simple Western; WB | |
NONE | PE Linked-Polyclonal Antibody to Early Growth Response Protein 2 (EGR2) | Flow Cytometry | |
NONE | FITC Linked-Polyclonal Antibody to Early Growth Response Protein 2 (EGR2) | Flow Cytometry;ICC/IF | |
Assay Kits | NONE | ELISA Kit for Early Growth Response Protein 2 (EGR2) | Enzyme-linked immunosorbent assay for Antigen Detection |
NONE | CLIA kit for Early Growth Response Protein 2 (EGR2) | CLIA assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | NONE | Recombinant Early Growth Response Protein 2 (EGR2) | Positive Control; Immunogen; SDS-PAGE; WB. |
NONE | Native Early Growth Response Protein 2 (EGR2) | Bioactivity | |
Antibodies | NONE | Monoclonal Antibody to Early Growth Response Protein 2 (EGR2) | WB; IHC; ICC; IP. |
NONE | Polyclonal Antibody to Early Growth Response Protein 2 (EGR2) | WB; IHC; ICC; IF. | |
NONE | Biotin Linked-Polyclonal Antibody to Early Growth Response Protein 2 (EGR2) | ELISA(Det);IC; IH; IH(P); WB | |
NONE | APC Linked-Polyclonal Antibody to Early Growth Response Protein 2 (EGR2) | IHC, WB | |
NONE | HRP Linked-Polyclonal Antibody to Early Growth Response Protein 2 (EGR2) | Simple Western; WB | |
NONE | PE Linked-Polyclonal Antibody to Early Growth Response Protein 2 (EGR2) | Flow Cytometry | |
NONE | FITC Linked-Polyclonal Antibody to Early Growth Response Protein 2 (EGR2) | Flow Cytometry;ICC/IF | |
Assay Kits | NONE | ELISA Kit for Early Growth Response Protein 2 (EGR2) | Enzyme-linked immunosorbent assay for Antigen Detection |
NONE | CLIA kit for Early Growth Response Protein 2 (EGR2) | CLIA assay for Antigen Detection |
Organism species: Chicken (Gallus)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | NONE | Recombinant Early Growth Response Protein 2 (EGR2) | Positive Control; Immunogen; SDS-PAGE; WB. |
NONE | Native Early Growth Response Protein 2 (EGR2) | Bioactivity | |
Antibodies | NONE | Monoclonal Antibody to Early Growth Response Protein 2 (EGR2) | WB; IHC; ICC; IP. |
NONE | Polyclonal Antibody to Early Growth Response Protein 2 (EGR2) | WB; IHC; ICC; IF. | |
NONE | Biotin Linked-Polyclonal Antibody to Early Growth Response Protein 2 (EGR2) | ELISA(Det);IC; IH; IH(P); WB | |
NONE | APC Linked-Polyclonal Antibody to Early Growth Response Protein 2 (EGR2) | IHC, WB | |
NONE | HRP Linked-Polyclonal Antibody to Early Growth Response Protein 2 (EGR2) | Simple Western; WB | |
NONE | PE Linked-Polyclonal Antibody to Early Growth Response Protein 2 (EGR2) | Flow Cytometry | |
NONE | FITC Linked-Polyclonal Antibody to Early Growth Response Protein 2 (EGR2) | Flow Cytometry;ICC/IF | |
Assay Kits | NONE | ELISA Kit for Early Growth Response Protein 2 (EGR2) | Enzyme-linked immunosorbent assay for Antigen Detection |
NONE | CLIA kit for Early Growth Response Protein 2 (EGR2) | CLIA assay for Antigen Detection |
Organism species: Ovis aries; Ovine (Sheep)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | NONE | Recombinant Early Growth Response Protein 2 (EGR2) | Positive Control; Immunogen; SDS-PAGE; WB. |
NONE | Native Early Growth Response Protein 2 (EGR2) | Bioactivity | |
Antibodies | NONE | Monoclonal Antibody to Early Growth Response Protein 2 (EGR2) | WB; IHC; ICC; IP. |
NONE | Polyclonal Antibody to Early Growth Response Protein 2 (EGR2) | WB; IHC; ICC; IF. | |
NONE | Biotin Linked-Polyclonal Antibody to Early Growth Response Protein 2 (EGR2) | ELISA(Det);IC; IH; IH(P); WB | |
NONE | APC Linked-Polyclonal Antibody to Early Growth Response Protein 2 (EGR2) | IHC, WB | |
NONE | HRP Linked-Polyclonal Antibody to Early Growth Response Protein 2 (EGR2) | Simple Western; WB | |
NONE | PE Linked-Polyclonal Antibody to Early Growth Response Protein 2 (EGR2) | Flow Cytometry | |
NONE | FITC Linked-Polyclonal Antibody to Early Growth Response Protein 2 (EGR2) | Flow Cytometry;ICC/IF | |
Assay Kits | NONE | ELISA Kit for Early Growth Response Protein 2 (EGR2) | Enzyme-linked immunosorbent assay for Antigen Detection |
NONE | CLIA kit for Early Growth Response Protein 2 (EGR2) | CLIA assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | NONE | Recombinant Early Growth Response Protein 2 (EGR2) | Positive Control; Immunogen; SDS-PAGE; WB. |
NONE | Native Early Growth Response Protein 2 (EGR2) | Bioactivity | |
Antibodies | NONE | Monoclonal Antibody to Early Growth Response Protein 2 (EGR2) | WB; IHC; ICC; IP. |
NONE | Polyclonal Antibody to Early Growth Response Protein 2 (EGR2) | WB; IHC; ICC; IF. | |
NONE | Biotin Linked-Polyclonal Antibody to Early Growth Response Protein 2 (EGR2) | ELISA(Det);IC; IH; IH(P); WB | |
NONE | APC Linked-Polyclonal Antibody to Early Growth Response Protein 2 (EGR2) | IHC, WB | |
NONE | HRP Linked-Polyclonal Antibody to Early Growth Response Protein 2 (EGR2) | Simple Western; WB | |
NONE | PE Linked-Polyclonal Antibody to Early Growth Response Protein 2 (EGR2) | Flow Cytometry | |
NONE | FITC Linked-Polyclonal Antibody to Early Growth Response Protein 2 (EGR2) | Flow Cytometry;ICC/IF | |
Assay Kits | NONE | ELISA Kit for Early Growth Response Protein 2 (EGR2) | Enzyme-linked immunosorbent assay for Antigen Detection |
NONE | CLIA kit for Early Growth Response Protein 2 (EGR2) | CLIA assay for Antigen Detection |
Organism species: Cavia (Guinea pig )
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | NONE | Recombinant Early Growth Response Protein 2 (EGR2) | Positive Control; Immunogen; SDS-PAGE; WB. |
NONE | Native Early Growth Response Protein 2 (EGR2) | Bioactivity | |
Antibodies | NONE | Monoclonal Antibody to Early Growth Response Protein 2 (EGR2) | WB; IHC; ICC; IP. |
NONE | Polyclonal Antibody to Early Growth Response Protein 2 (EGR2) | WB; IHC; ICC; IF. | |
NONE | Biotin Linked-Polyclonal Antibody to Early Growth Response Protein 2 (EGR2) | ELISA(Det);IC; IH; IH(P); WB | |
NONE | APC Linked-Polyclonal Antibody to Early Growth Response Protein 2 (EGR2) | IHC, WB | |
NONE | HRP Linked-Polyclonal Antibody to Early Growth Response Protein 2 (EGR2) | Simple Western; WB | |
NONE | PE Linked-Polyclonal Antibody to Early Growth Response Protein 2 (EGR2) | Flow Cytometry | |
NONE | FITC Linked-Polyclonal Antibody to Early Growth Response Protein 2 (EGR2) | Flow Cytometry;ICC/IF | |
Assay Kits | NONE | ELISA Kit for Early Growth Response Protein 2 (EGR2) | Enzyme-linked immunosorbent assay for Antigen Detection |
NONE | CLIA kit for Early Growth Response Protein 2 (EGR2) | CLIA assay for Antigen Detection |
Organism species: Equus caballus; Equine (Horse)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | NONE | Recombinant Early Growth Response Protein 2 (EGR2) | Positive Control; Immunogen; SDS-PAGE; WB. |
NONE | Native Early Growth Response Protein 2 (EGR2) | Bioactivity | |
Antibodies | NONE | Monoclonal Antibody to Early Growth Response Protein 2 (EGR2) | WB; IHC; ICC; IP. |
NONE | Polyclonal Antibody to Early Growth Response Protein 2 (EGR2) | WB; IHC; ICC; IF. | |
NONE | Biotin Linked-Polyclonal Antibody to Early Growth Response Protein 2 (EGR2) | ELISA(Det);IC; IH; IH(P); WB | |
NONE | APC Linked-Polyclonal Antibody to Early Growth Response Protein 2 (EGR2) | IHC, WB | |
NONE | HRP Linked-Polyclonal Antibody to Early Growth Response Protein 2 (EGR2) | Simple Western; WB | |
NONE | PE Linked-Polyclonal Antibody to Early Growth Response Protein 2 (EGR2) | Flow Cytometry | |
NONE | FITC Linked-Polyclonal Antibody to Early Growth Response Protein 2 (EGR2) | Flow Cytometry;ICC/IF | |
Assay Kits | NONE | ELISA Kit for Early Growth Response Protein 2 (EGR2) | Enzyme-linked immunosorbent assay for Antigen Detection |
NONE | CLIA kit for Early Growth Response Protein 2 (EGR2) | CLIA assay for Antigen Detection |
Organism species: Capra hircus; Caprine (Goat)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | NONE | Recombinant Early Growth Response Protein 2 (EGR2) | Positive Control; Immunogen; SDS-PAGE; WB. |
NONE | Native Early Growth Response Protein 2 (EGR2) | Bioactivity | |
Antibodies | NONE | Monoclonal Antibody to Early Growth Response Protein 2 (EGR2) | WB; IHC; ICC; IP. |
NONE | Polyclonal Antibody to Early Growth Response Protein 2 (EGR2) | WB; IHC; ICC; IF. | |
NONE | Biotin Linked-Polyclonal Antibody to Early Growth Response Protein 2 (EGR2) | ELISA(Det);IC; IH; IH(P); WB | |
NONE | APC Linked-Polyclonal Antibody to Early Growth Response Protein 2 (EGR2) | IHC, WB | |
NONE | HRP Linked-Polyclonal Antibody to Early Growth Response Protein 2 (EGR2) | Simple Western; WB | |
NONE | PE Linked-Polyclonal Antibody to Early Growth Response Protein 2 (EGR2) | Flow Cytometry | |
NONE | FITC Linked-Polyclonal Antibody to Early Growth Response Protein 2 (EGR2) | Flow Cytometry;ICC/IF | |
Assay Kits | NONE | ELISA Kit for Early Growth Response Protein 2 (EGR2) | Enzyme-linked immunosorbent assay for Antigen Detection |
NONE | CLIA kit for Early Growth Response Protein 2 (EGR2) | CLIA assay for Antigen Detection |
Organism species: Pan-species (General)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | NONE | Recombinant Early Growth Response Protein 2 (EGR2) | Positive Control; Immunogen; SDS-PAGE; WB. |
NONE | Native Early Growth Response Protein 2 (EGR2) | Bioactivity | |
Antibodies | NONE | Monoclonal Antibody to Early Growth Response Protein 2 (EGR2) | WB; IHC; ICC; IP. |
NONE | Polyclonal Antibody to Early Growth Response Protein 2 (EGR2) | WB; IHC; ICC; IF. | |
NONE | Biotin Linked-Polyclonal Antibody to Early Growth Response Protein 2 (EGR2) | ELISA(Det);IC; IH; IH(P); WB | |
NONE | APC Linked-Polyclonal Antibody to Early Growth Response Protein 2 (EGR2) | IHC, WB | |
NONE | HRP Linked-Polyclonal Antibody to Early Growth Response Protein 2 (EGR2) | Simple Western; WB | |
NONE | PE Linked-Polyclonal Antibody to Early Growth Response Protein 2 (EGR2) | Flow Cytometry | |
NONE | FITC Linked-Polyclonal Antibody to Early Growth Response Protein 2 (EGR2) | Flow Cytometry;ICC/IF | |
Assay Kits | NONE | ELISA Kit for Early Growth Response Protein 2 (EGR2) | Enzyme-linked immunosorbent assay for Antigen Detection |
NONE | CLIA kit for Early Growth Response Protein 2 (EGR2) | CLIA assay for Antigen Detection |
Reference
"Molecular cloning, sequencing, and mapping of EGR2, a human early growth response gene encoding a protein with 'zinc-binding finger' structure."
Proc. Natl. Acad. Sci. U.S.A. 85:7164-7168(1988) [PubMed] [Europe PMC] [Abstract]
Erratum
Proc. Natl. Acad. Sci. U.S.A. 86:515-515(1989)
"Mutations in the early growth response 2 (EGR2) gene are associated with hereditary myelinopathies."
Nat. Genet. 18:382-384(1998) [PubMed] [Europe PMC] [Abstract]
"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
"The full-ORF clone resource of the German cDNA consortium."
BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
"The DNA sequence and comparative analysis of human chromosome 10."
Nature 429:375-381(2004) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"The serum and TPA responsive promoter and intron-exon structure of EGR2, a human early growth response gene encoding a zinc finger protein."
Nucleic Acids Res. 18:2749-2757(1990) [PubMed] [Europe PMC] [Abstract]
"HCF-1 functions as a coactivator for the zinc finger protein Krox20."
J. Biol. Chem. 278:51116-51124(2003) [PubMed] [Europe PMC] [Abstract]
"The HECT-type E3 ubiquitin ligase AIP2 inhibits activation-induced T-cell death by catalyzing EGR2 ubiquitination."
Mol. Cell. Biol. 29:5348-5356(2009) [PubMed] [Europe PMC] [Abstract]
"Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
"The transcription factor Krox20 is an E3 ligase that sumoylates its Nab coregulators."
EMBO Rep. 12:1018-1023(2011) [PubMed] [Europe PMC] [Abstract]
"Homozygous deletion of an EGR2 enhancer in congenital amyelinating neuropathy."
Ann. Neurol. 71:719-723(2012) [PubMed] [Europe PMC] [Abstract]
"EGR2 gene mutation in a patient affected with Charcot-Marie-Tooth type 1."
Eur. J. Hum. Genet. Suppl. 7:99-99(1999)
"A novel mutation (D305V) in the early growth response 2 gene is associated with severe Charcot-Marie-Tooth type 1 disease."
Hum. Mutat. 14:353-354(1999) [PubMed] [Europe PMC] [Abstract]
"Novel missense mutation in the early growth response 2 gene associated with Dejerine-Sottas syndrome phenotype."
Neurology 52:1827-1832(1999) [PubMed] [Europe PMC] [Abstract]
"Cranial nerve involvement in CMT disease type 1 due to early growth response 2 gene mutation."
Neurology 54:1696-1698(2000) [PubMed] [Europe PMC] [Abstract]
"A novel missense mutation in the early growth response 2 gene associated with late-onset Charcot-Marie-Tooth disease type 1."
J. Neurol. Sci. 184:149-153(2001) [PubMed] [Europe PMC] [Abstract]
"Screening of the early growth response 2 gene in Japanese patients with Charcot-Marie-Tooth disease type 1."
J. Neurol. Sci. 210:61-64(2003) [PubMed] [Europe PMC] [Abstract]
"Mutational analysis of PMP22, MPZ, GJB1, EGR2 and NEFL in Korean Charcot-Marie-Tooth neuropathy patients."
Hum. Mutat. 24:185-186(2004) [PubMed] [Europe PMC] [Abstract]
"Two missense mutations of EGR2 R359W and GJB1 V136A in a Charcot-Marie-Tooth disease family."
Neurogenetics 6:159-163(2005) [PubMed] [Europe PMC] [Abstract]