Lipase, Pancreatic (PL)
PNLIP; PTL; Pancreatic Lipase; Pancreatic triacylglycerol lipase
Pancreatic lipase is an enzyme secreted from the pancreas that uses hydrolysis to break apart fat molecules. Bile salts secreted from the liver and stored in gallbladder are released into the duodenum where they coat fat droplets. Because the droplets are small, their surface area is greater, allowing the lipase to break apart the fat more effectively. The resulting monomers are then moved by way of peristalsis along the small intestine to be absorbed into the lymphatic system by a specialized vessel called a lacteal. Pancreatic lipase is secreted into the duodenum through the duct system of the pancreas. Normally its concentration in serum is very low. Under extreme disruption of pancreatic function, such as pancreatitis or pancreatic adenocarcinoma.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV381Hu01 | Recombinant Lipase, Pancreatic (PL) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV381Hu01 | Monoclonal Antibody to Lipase, Pancreatic (PL) | WB; IHC; ICC; IP. |
| PAV381Hu01 | Polyclonal Antibody to Lipase, Pancreatic (PL) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV381Hu01 | CLIA Kit for Lipase, Pancreatic (PL) | CLIA assay for Antigen Detection |
| ELV381Hu01 | ELISA Kit for Lipase, Pancreatic (PL) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV381Mu01 | Recombinant Lipase, Pancreatic (PL) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV381Mu01 | Monoclonal Antibody to Lipase, Pancreatic (PL) | WB; IHC; ICC; IP. |
| PAV381Mu01 | Polyclonal Antibody to Lipase, Pancreatic (PL) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV381Mu01 | CLIA Kit for Lipase, Pancreatic (PL) | CLIA assay for Antigen Detection |
| ELV381Mu01 | ELISA Kit for Lipase, Pancreatic (PL) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV381Ra01 | Recombinant Lipase, Pancreatic (PL) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV381Ra01 | Monoclonal Antibody to Lipase, Pancreatic (PL) | WB; IHC; ICC; IP. |
| PAV381Ra01 | Polyclonal Antibody to Lipase, Pancreatic (PL) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV381Ra01 | CLIA Kit for Lipase, Pancreatic (PL) | CLIA assay for Antigen Detection |
| ELV381Ra01 | ELISA Kit for Lipase, Pancreatic (PL) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV381Ca01 | Recombinant Lipase, Pancreatic (PL) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV381Ca01 | Monoclonal Antibody to Lipase, Pancreatic (PL) | WB; IHC; ICC; IP. |
| PAV381Ca01 | Polyclonal Antibody to Lipase, Pancreatic (PL) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV381Ca01 | CLIA Kit for Lipase, Pancreatic (PL) | CLIA assay for Antigen Detection |
| ELV381Ca01 | ELISA Kit for Lipase, Pancreatic (PL) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV381Po01 | Recombinant Lipase, Pancreatic (PL) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV381Po01 | Monoclonal Antibody to Lipase, Pancreatic (PL) | WB; IHC; ICC; IP. |
| PAV381Po01 | Polyclonal Antibody to Lipase, Pancreatic (PL) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV381Po01 | CLIA Kit for Lipase, Pancreatic (PL) | CLIA assay for Antigen Detection |
| ELV381Po01 | ELISA Kit for Lipase, Pancreatic (PL) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV381Bo01 | Recombinant Lipase, Pancreatic (PL) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV381Bo01 | Monoclonal Antibody to Lipase, Pancreatic (PL) | WB; IHC; ICC; IP. |
| PAV381Bo01 | Polyclonal Antibody to Lipase, Pancreatic (PL) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV381Bo01 | CLIA Kit for Lipase, Pancreatic (PL) | CLIA assay for Antigen Detection |
| ELV381Bo01 | ELISA Kit for Lipase, Pancreatic (PL) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV381Rb01 | Recombinant Lipase, Pancreatic (PL) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV381Rb01 | Monoclonal Antibody to Lipase, Pancreatic (PL) | WB; IHC; ICC; IP. |
| PAV381Rb01 | Polyclonal Antibody to Lipase, Pancreatic (PL) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV381Rb01 | CLIA Kit for Lipase, Pancreatic (PL) | CLIA assay for Antigen Detection |
| ELV381Rb01 | ELISA Kit for Lipase, Pancreatic (PL) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV381Mo01 | Recombinant Lipase, Pancreatic (PL) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV381Mo01 | Monoclonal Antibody to Lipase, Pancreatic (PL) | WB; IHC; ICC; IP. |
| PAV381Mo01 | Polyclonal Antibody to Lipase, Pancreatic (PL) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV381Mo01 | CLIA Kit for Lipase, Pancreatic (PL) | CLIA assay for Antigen Detection |
| ELV381Mo01 | ELISA Kit for Lipase, Pancreatic (PL) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"Cloning and characterization of human pancreatic lipase cDNA."
J. Biol. Chem. 264:20042-20048(1989) [PubMed] [Europe PMC] [Abstract]
"Two novel human pancreatic lipase related proteins, hPLRP1 and hPLRP2. Differences in colipase dependence and in lipase activity."
J. Biol. Chem. 267:16509-16516(1992) [PubMed] [Europe PMC] [Abstract]
"The human pancreatic lipase-encoding gene: structure and conservation of an Alu sequence in the lipase gene family."
Gene 131:281-285(1993) [PubMed] [Europe PMC] [Abstract]
"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
"The DNA sequence and comparative analysis of human chromosome 10."
Nature 429:375-381(2004) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"Hydrolysis of retinyl esters by pancreatic triglyceride lipase."
Biochemistry 39:4900-4906(2000) [PubMed] [Europe PMC] [Abstract]
"Structure of human pancreatic lipase."
Nature 343:771-774(1990) [PubMed] [Europe PMC] [Abstract]
"Structure of the pancreatic lipase-procolipase complex."
Nature 359:159-162(1992) [PubMed] [Europe PMC] [Abstract]
"Interfacial activation of the lipase-procolipase complex by mixed micelles revealed by X-ray crystallography."
Nature 362:814-820(1993) [PubMed] [Europe PMC] [Abstract]
"Structure-function relationships in naturally occurring mutants of pancreatic lipase."
Protein Eng. 7:563-569(1994) [PubMed] [Europe PMC] [Abstract]