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Connexin 37 (CX37)

GJA4; GJ-A4; Gap Junction Protein Alpha 4

Gap junction alpha-4 protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Mutations in this gene have been associated with atherosclerosis and a higher risk of myocardial infarction.

Reed et al. (1993) used PCR amplification and cDNA library screening to clone DNA encoding the connexin 37 gap junction protein. The derived polypeptide contained 333 amino acids, with a predicted molecular mass of about 37 kD. RNA blots demonstrated that CX37 is expressed in multiple organs and tissues, including heart, uterus, ovary, and blood vessel endothelium, and in primary cultures of vascular endothelial cells.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Connexin 37 (CX37) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Connexin 37 (CX37) Bioactivity
Antibodies MV368Hu21 Monoclonal Antibody to Connexin 37 (CX37) WB; IHC; ICC; IP.
PV368Hu01 Polyclonal Antibody to Connexin 37 (CX37) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Connexin 37 (CX37) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Connexin 37 (CX37) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Connexin 37 (CX37) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Connexin 37 (CX37) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Connexin 37 (CX37) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Connexin 37 (CX37) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Connexin 37 (CX37) CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins V368Mu01 Recombinant Connexin 37 (CX37) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Connexin 37 (CX37) Bioactivity
Antibodies NONE Monoclonal Antibody to Connexin 37 (CX37) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Connexin 37 (CX37) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Connexin 37 (CX37) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Connexin 37 (CX37) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Connexin 37 (CX37) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Connexin 37 (CX37) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Connexin 37 (CX37) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Connexin 37 (CX37) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Connexin 37 (CX37) CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Connexin 37 (CX37) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Connexin 37 (CX37) Bioactivity
Antibodies NONE Monoclonal Antibody to Connexin 37 (CX37) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Connexin 37 (CX37) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Connexin 37 (CX37) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Connexin 37 (CX37) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Connexin 37 (CX37) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Connexin 37 (CX37) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Connexin 37 (CX37) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Connexin 37 (CX37) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Connexin 37 (CX37) CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Connexin 37 (CX37) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Connexin 37 (CX37) Bioactivity
Antibodies NONE Monoclonal Antibody to Connexin 37 (CX37) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Connexin 37 (CX37) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Connexin 37 (CX37) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Connexin 37 (CX37) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Connexin 37 (CX37) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Connexin 37 (CX37) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Connexin 37 (CX37) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Connexin 37 (CX37) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Connexin 37 (CX37) CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Connexin 37 (CX37) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Connexin 37 (CX37) Bioactivity
Antibodies NONE Monoclonal Antibody to Connexin 37 (CX37) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Connexin 37 (CX37) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Connexin 37 (CX37) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Connexin 37 (CX37) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Connexin 37 (CX37) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Connexin 37 (CX37) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Connexin 37 (CX37) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Connexin 37 (CX37) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Connexin 37 (CX37) CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Connexin 37 (CX37) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Connexin 37 (CX37) Bioactivity
Antibodies NONE Monoclonal Antibody to Connexin 37 (CX37) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Connexin 37 (CX37) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Connexin 37 (CX37) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Connexin 37 (CX37) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Connexin 37 (CX37) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Connexin 37 (CX37) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Connexin 37 (CX37) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Connexin 37 (CX37) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Connexin 37 (CX37) CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Connexin 37 (CX37) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Connexin 37 (CX37) Bioactivity
Antibodies NONE Monoclonal Antibody to Connexin 37 (CX37) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Connexin 37 (CX37) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Connexin 37 (CX37) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Connexin 37 (CX37) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Connexin 37 (CX37) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Connexin 37 (CX37) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Connexin 37 (CX37) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Connexin 37 (CX37) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Connexin 37 (CX37) CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Connexin 37 (CX37) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Connexin 37 (CX37) Bioactivity
Antibodies NONE Monoclonal Antibody to Connexin 37 (CX37) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Connexin 37 (CX37) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Connexin 37 (CX37) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Connexin 37 (CX37) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Connexin 37 (CX37) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Connexin 37 (CX37) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Connexin 37 (CX37) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Connexin 37 (CX37) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Connexin 37 (CX37) CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Connexin 37 (CX37) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Connexin 37 (CX37) Bioactivity
Antibodies NONE Monoclonal Antibody to Connexin 37 (CX37) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Connexin 37 (CX37) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Connexin 37 (CX37) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Connexin 37 (CX37) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Connexin 37 (CX37) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Connexin 37 (CX37) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Connexin 37 (CX37) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Connexin 37 (CX37) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Connexin 37 (CX37) CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Connexin 37 (CX37) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Connexin 37 (CX37) Bioactivity
Antibodies NONE Monoclonal Antibody to Connexin 37 (CX37) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Connexin 37 (CX37) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Connexin 37 (CX37) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Connexin 37 (CX37) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Connexin 37 (CX37) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Connexin 37 (CX37) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Connexin 37 (CX37) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Connexin 37 (CX37) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Connexin 37 (CX37) CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Connexin 37 (CX37) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Connexin 37 (CX37) Bioactivity
Antibodies NONE Monoclonal Antibody to Connexin 37 (CX37) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Connexin 37 (CX37) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Connexin 37 (CX37) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Connexin 37 (CX37) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Connexin 37 (CX37) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Connexin 37 (CX37) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Connexin 37 (CX37) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Connexin 37 (CX37) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Connexin 37 (CX37) CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Connexin 37 (CX37) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Connexin 37 (CX37) Bioactivity
Antibodies NONE Monoclonal Antibody to Connexin 37 (CX37) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Connexin 37 (CX37) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Connexin 37 (CX37) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Connexin 37 (CX37) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Connexin 37 (CX37) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Connexin 37 (CX37) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Connexin 37 (CX37) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Connexin 37 (CX37) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Connexin 37 (CX37) CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Connexin 37 (CX37) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Connexin 37 (CX37) Bioactivity
Antibodies NONE Monoclonal Antibody to Connexin 37 (CX37) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Connexin 37 (CX37) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Connexin 37 (CX37) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Connexin 37 (CX37) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Connexin 37 (CX37) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Connexin 37 (CX37) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Connexin 37 (CX37) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Connexin 37 (CX37) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Connexin 37 (CX37) CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Connexin 37 (CX37) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Connexin 37 (CX37) Bioactivity
Antibodies NONE Monoclonal Antibody to Connexin 37 (CX37) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Connexin 37 (CX37) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Connexin 37 (CX37) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Connexin 37 (CX37) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Connexin 37 (CX37) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Connexin 37 (CX37) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Connexin 37 (CX37) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Connexin 37 (CX37) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Connexin 37 (CX37) CLIA assay for Antigen Detection

Reference

"Molecular cloning and functional expression of human connexin37, an endothelial cell gap junction protein."
J. Clin. Invest. 91:997-1004(1993) [PubMed] [Europe PMC] [Abstract]

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

"The DNA sequence and biological annotation of human chromosome 1."
Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Human connexin 37 is polymorphic but not mutated in tumours."
Carcinogenesis 17:1761-1763(1996) [PubMed] [Europe PMC] [Abstract]

"A genetic polymorphism in connexin 37 as a prognostic marker for atherosclerotic plaque development."
J. Intern. Med. 246:211-218(1999) [PubMed] [Europe PMC] [Abstract]

"Human hemangiosarcomas have a common polymorphism but no mutations in the connexin37 gene."
Int. J. Cancer 86:67-70(2000) [PubMed] [Europe PMC] [Abstract]