Pitrilysin Metalloproteinase 1 (MP1)
PITRM1; hMP1; PreP; PreP Peptidasome; Presequence protease, mitochondrial; Metalloprotease 1
The phosphofructokinase (PFK) C (Pfkp) and the pitrilysin metalloprotease 1 (Pitrm1) genes are compelling positional candidate genes in this region that show coding sequence differences between the parental strains in functional domains.
ATP-independent protease that degrades mitochondrial transit peptides after their cleavage. Also degrades other unstructured peptides. Specific for peptides in the range of 10 to 65 residues. Able to degrade amyloid beta A4 (APP) protein when it accumulates in mitochondrion, suggesting a link with Alzheimer disease. Shows a preference for cleavage after small polar residues and before basic residues, but without any positional preference. Widely expressed. Expressed at higher level in muscle and heart compared to brain, pancreas, liver, lung and placenta.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV361Hu01 | Recombinant Pitrilysin Metalloproteinase 1 (MP1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV361Hu01 | Monoclonal Antibody to Pitrilysin Metalloproteinase 1 (MP1) | WB; IHC; ICC; IP. |
| PAV361Hu01 | Polyclonal Antibody to Pitrilysin Metalloproteinase 1 (MP1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV361Hu01 | CLIA Kit for Pitrilysin Metalloproteinase 1 (MP1) | CLIA assay for Antigen Detection |
| ELV361Hu01 | ELISA Kit for Pitrilysin Metalloproteinase 1 (MP1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV361Mu01 | Recombinant Pitrilysin Metalloproteinase 1 (MP1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV361Mu01 | Monoclonal Antibody to Pitrilysin Metalloproteinase 1 (MP1) | WB; IHC; ICC; IP. |
| PAV361Mu01 | Polyclonal Antibody to Pitrilysin Metalloproteinase 1 (MP1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV361Mu01 | CLIA Kit for Pitrilysin Metalloproteinase 1 (MP1) | CLIA assay for Antigen Detection |
| ELV361Mu01 | ELISA Kit for Pitrilysin Metalloproteinase 1 (MP1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV361Ra01 | Recombinant Pitrilysin Metalloproteinase 1 (MP1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV361Ra01 | Monoclonal Antibody to Pitrilysin Metalloproteinase 1 (MP1) | WB; IHC; ICC; IP. |
| PAV361Ra01 | Polyclonal Antibody to Pitrilysin Metalloproteinase 1 (MP1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV361Ra01 | CLIA Kit for Pitrilysin Metalloproteinase 1 (MP1) | CLIA assay for Antigen Detection |
| ELV361Ra01 | ELISA Kit for Pitrilysin Metalloproteinase 1 (MP1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV361Ca01 | Recombinant Pitrilysin Metalloproteinase 1 (MP1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV361Ca01 | Monoclonal Antibody to Pitrilysin Metalloproteinase 1 (MP1) | WB; IHC; ICC; IP. |
| PAV361Ca01 | Polyclonal Antibody to Pitrilysin Metalloproteinase 1 (MP1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV361Ca01 | CLIA Kit for Pitrilysin Metalloproteinase 1 (MP1) | CLIA assay for Antigen Detection |
| ELV361Ca01 | ELISA Kit for Pitrilysin Metalloproteinase 1 (MP1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV361Po01 | Recombinant Pitrilysin Metalloproteinase 1 (MP1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV361Po01 | Monoclonal Antibody to Pitrilysin Metalloproteinase 1 (MP1) | WB; IHC; ICC; IP. |
| PAV361Po01 | Polyclonal Antibody to Pitrilysin Metalloproteinase 1 (MP1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV361Po01 | CLIA Kit for Pitrilysin Metalloproteinase 1 (MP1) | CLIA assay for Antigen Detection |
| ELV361Po01 | ELISA Kit for Pitrilysin Metalloproteinase 1 (MP1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV361Bo01 | Recombinant Pitrilysin Metalloproteinase 1 (MP1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV361Bo01 | Monoclonal Antibody to Pitrilysin Metalloproteinase 1 (MP1) | WB; IHC; ICC; IP. |
| PAV361Bo01 | Polyclonal Antibody to Pitrilysin Metalloproteinase 1 (MP1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV361Bo01 | CLIA Kit for Pitrilysin Metalloproteinase 1 (MP1) | CLIA assay for Antigen Detection |
| ELV361Bo01 | ELISA Kit for Pitrilysin Metalloproteinase 1 (MP1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV361Rb01 | Recombinant Pitrilysin Metalloproteinase 1 (MP1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV361Rb01 | Monoclonal Antibody to Pitrilysin Metalloproteinase 1 (MP1) | WB; IHC; ICC; IP. |
| PAV361Rb01 | Polyclonal Antibody to Pitrilysin Metalloproteinase 1 (MP1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV361Rb01 | CLIA Kit for Pitrilysin Metalloproteinase 1 (MP1) | CLIA assay for Antigen Detection |
| ELV361Rb01 | ELISA Kit for Pitrilysin Metalloproteinase 1 (MP1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV361Mo01 | Recombinant Pitrilysin Metalloproteinase 1 (MP1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV361Mo01 | Monoclonal Antibody to Pitrilysin Metalloproteinase 1 (MP1) | WB; IHC; ICC; IP. |
| PAV361Mo01 | Polyclonal Antibody to Pitrilysin Metalloproteinase 1 (MP1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV361Mo01 | CLIA Kit for Pitrilysin Metalloproteinase 1 (MP1) | CLIA assay for Antigen Detection |
| ELV361Mo01 | ELISA Kit for Pitrilysin Metalloproteinase 1 (MP1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
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