Cadherin, Neuronal (CDH2)

CDw325; CD325; CDHN; NCAD; Cadherin 2 Type 1; N-Cadherin

SPN	V353
HGNC	1759
MGI	88355
PubMed	23321619
RGD	69280
UniProt	P19022
Wiki	CDH2

Cadherin 2, type 1, N-cadherin (neuronal), is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprising five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. The protein functions during gastrulation and is required for establishment of left-right asymmetry. At certain central nervous system synapses, presynaptic to postsynaptic adhesion is mediated at least in part by this gene product. Reid and Hemperly (1990) obtained a full-length NCAD clone from a Kelly neuroblastoma library. The NCAD gene encodes a 907-amino acid protein that includes a 159-amino acid signal sequence. Human and mouse nucleotide sequences are 96% identical.

Organism species: Homo sapiens (Human)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	V353Hu01	Recombinant Cadherin, Neuronal (CDH2)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Cadherin, Neuronal (CDH2)	Bioactivity
Antibodies	MV353Hu22	Monoclonal Antibody to Cadherin, Neuronal (CDH2)	WB; IHC; ICC; IP.
	PV353Hu01	Polyclonal Antibody to Cadherin, Neuronal (CDH2)	WB; IHC; ICC; IF.
	LV353Hu71	Biotin Linked-Polyclonal Antibody to Cadherin, Neuronal (CDH2)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Cadherin, Neuronal (CDH2)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Cadherin, Neuronal (CDH2)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Cadherin, Neuronal (CDH2)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Cadherin, Neuronal (CDH2)	Flow Cytometry;ICC/IF
Assay Kits	KEV353Hu	ELISA Kit for Cadherin, Neuronal (CDH2)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Cadherin, Neuronal (CDH2)	CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Cadherin, Neuronal (CDH2)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Cadherin, Neuronal (CDH2)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Cadherin, Neuronal (CDH2)	WB; IHC; ICC; IP.
	PV353Mu01	Polyclonal Antibody to Cadherin, Neuronal (CDH2)	WB; IHC; ICC; IF.
	LV353Mu71	Biotin Linked-Polyclonal Antibody to Cadherin, Neuronal (CDH2)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Cadherin, Neuronal (CDH2)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Cadherin, Neuronal (CDH2)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Cadherin, Neuronal (CDH2)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Cadherin, Neuronal (CDH2)	Flow Cytometry;ICC/IF
Assay Kits	KEV353Mu	ELISA Kit for Cadherin, Neuronal (CDH2)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Cadherin, Neuronal (CDH2)	CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Cadherin, Neuronal (CDH2)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Cadherin, Neuronal (CDH2)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Cadherin, Neuronal (CDH2)	WB; IHC; ICC; IP.
	PV353Ra01	Polyclonal Antibody to Cadherin, Neuronal (CDH2)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Cadherin, Neuronal (CDH2)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Cadherin, Neuronal (CDH2)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Cadherin, Neuronal (CDH2)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Cadherin, Neuronal (CDH2)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Cadherin, Neuronal (CDH2)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Cadherin, Neuronal (CDH2)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Cadherin, Neuronal (CDH2)	CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Cadherin, Neuronal (CDH2)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Cadherin, Neuronal (CDH2)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Cadherin, Neuronal (CDH2)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Cadherin, Neuronal (CDH2)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Cadherin, Neuronal (CDH2)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Cadherin, Neuronal (CDH2)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Cadherin, Neuronal (CDH2)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Cadherin, Neuronal (CDH2)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Cadherin, Neuronal (CDH2)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Cadherin, Neuronal (CDH2)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Cadherin, Neuronal (CDH2)	CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Cadherin, Neuronal (CDH2)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Cadherin, Neuronal (CDH2)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Cadherin, Neuronal (CDH2)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Cadherin, Neuronal (CDH2)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Cadherin, Neuronal (CDH2)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Cadherin, Neuronal (CDH2)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Cadherin, Neuronal (CDH2)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Cadherin, Neuronal (CDH2)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Cadherin, Neuronal (CDH2)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Cadherin, Neuronal (CDH2)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Cadherin, Neuronal (CDH2)	CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Cadherin, Neuronal (CDH2)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Cadherin, Neuronal (CDH2)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Cadherin, Neuronal (CDH2)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Cadherin, Neuronal (CDH2)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Cadherin, Neuronal (CDH2)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Cadherin, Neuronal (CDH2)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Cadherin, Neuronal (CDH2)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Cadherin, Neuronal (CDH2)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Cadherin, Neuronal (CDH2)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Cadherin, Neuronal (CDH2)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Cadherin, Neuronal (CDH2)	CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Cadherin, Neuronal (CDH2)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Cadherin, Neuronal (CDH2)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Cadherin, Neuronal (CDH2)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Cadherin, Neuronal (CDH2)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Cadherin, Neuronal (CDH2)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Cadherin, Neuronal (CDH2)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Cadherin, Neuronal (CDH2)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Cadherin, Neuronal (CDH2)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Cadherin, Neuronal (CDH2)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Cadherin, Neuronal (CDH2)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Cadherin, Neuronal (CDH2)	CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Cadherin, Neuronal (CDH2)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Cadherin, Neuronal (CDH2)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Cadherin, Neuronal (CDH2)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Cadherin, Neuronal (CDH2)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Cadherin, Neuronal (CDH2)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Cadherin, Neuronal (CDH2)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Cadherin, Neuronal (CDH2)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Cadherin, Neuronal (CDH2)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Cadherin, Neuronal (CDH2)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Cadherin, Neuronal (CDH2)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Cadherin, Neuronal (CDH2)	CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Cadherin, Neuronal (CDH2)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Cadherin, Neuronal (CDH2)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Cadherin, Neuronal (CDH2)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Cadherin, Neuronal (CDH2)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Cadherin, Neuronal (CDH2)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Cadherin, Neuronal (CDH2)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Cadherin, Neuronal (CDH2)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Cadherin, Neuronal (CDH2)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Cadherin, Neuronal (CDH2)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Cadherin, Neuronal (CDH2)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Cadherin, Neuronal (CDH2)	CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Cadherin, Neuronal (CDH2)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Cadherin, Neuronal (CDH2)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Cadherin, Neuronal (CDH2)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Cadherin, Neuronal (CDH2)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Cadherin, Neuronal (CDH2)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Cadherin, Neuronal (CDH2)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Cadherin, Neuronal (CDH2)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Cadherin, Neuronal (CDH2)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Cadherin, Neuronal (CDH2)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Cadherin, Neuronal (CDH2)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Cadherin, Neuronal (CDH2)	CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Cadherin, Neuronal (CDH2)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Cadherin, Neuronal (CDH2)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Cadherin, Neuronal (CDH2)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Cadherin, Neuronal (CDH2)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Cadherin, Neuronal (CDH2)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Cadherin, Neuronal (CDH2)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Cadherin, Neuronal (CDH2)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Cadherin, Neuronal (CDH2)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Cadherin, Neuronal (CDH2)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Cadherin, Neuronal (CDH2)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Cadherin, Neuronal (CDH2)	CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Cadherin, Neuronal (CDH2)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Cadherin, Neuronal (CDH2)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Cadherin, Neuronal (CDH2)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Cadherin, Neuronal (CDH2)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Cadherin, Neuronal (CDH2)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Cadherin, Neuronal (CDH2)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Cadherin, Neuronal (CDH2)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Cadherin, Neuronal (CDH2)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Cadherin, Neuronal (CDH2)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Cadherin, Neuronal (CDH2)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Cadherin, Neuronal (CDH2)	CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Cadherin, Neuronal (CDH2)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Cadherin, Neuronal (CDH2)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Cadherin, Neuronal (CDH2)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Cadherin, Neuronal (CDH2)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Cadherin, Neuronal (CDH2)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Cadherin, Neuronal (CDH2)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Cadherin, Neuronal (CDH2)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Cadherin, Neuronal (CDH2)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Cadherin, Neuronal (CDH2)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Cadherin, Neuronal (CDH2)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Cadherin, Neuronal (CDH2)	CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Cadherin, Neuronal (CDH2)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Cadherin, Neuronal (CDH2)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Cadherin, Neuronal (CDH2)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Cadherin, Neuronal (CDH2)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Cadherin, Neuronal (CDH2)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Cadherin, Neuronal (CDH2)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Cadherin, Neuronal (CDH2)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Cadherin, Neuronal (CDH2)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Cadherin, Neuronal (CDH2)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Cadherin, Neuronal (CDH2)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Cadherin, Neuronal (CDH2)	CLIA assay for Antigen Detection

Reference

"Human N-cadherin: nucleotide and deduced amino acid sequence."
Nucleic Acids Res. 18:5896-5896(1990) [PubMed] [Europe PMC] [Abstract]

"Extrajunctional distribution of N-cadherin in cultured human endothelial cells."
J. Cell Sci. 102:7-17(1992) [PubMed] [Europe PMC] [Abstract]

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

"DNA sequence and analysis of human chromosome 18."
Nature 437:551-555(2005) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"N-cadherin gene maps to human chromosome 18 and is not linked to the E-cadherin gene."
J. Neurochem. 55:805-812(1990) [PubMed] [Europe PMC] [Abstract]

"Structure of the human N-cadherin gene: YAC analysis and fine chromosomal mapping to 18q11.2."
Genomics 22:172-179(1994) [PubMed] [Europe PMC] [Abstract]

"Adhesion signaling by a novel mitotic substrate of src kinases."
Oncogene 24:5333-5343(2005) [PubMed] [Europe PMC] [Abstract]

"Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."
J. Proteome Res. 8:651-661(2009) [PubMed] [Europe PMC] [Abstract]