Sorbitol Dehydrogenase (SDH)
SORD; L-iditol 2-dehydrogenase
Sorbitol dehydrogenase is an enzyme in carbohydrate metabolism converting sorbitol, the sugar alcohol form of glucose, into fructose. Together with aldose reductase, it provides a way for the body to produce fructose from glucose without using ATP. Sorbitol dehydrogenase uses NAD+ as a cofactor; its reaction is sorbitol + NAD+ + H+ --> fructose + NADH. A zinc ion is also involved in catalysis. Organs that use it most frequently include the liver and seminal vesicle; it is found in all kinds of organisms from bacteria to humans. A secondary use is the metabolism of dietary sorbitol, though sorbitol is known not to absorb as well in the intestine as its related compounds glucose and fructose, and is usually found in quite small amounts in the diet anyway (except when used as an artificial sweetener).
Organism species: Homo sapiens (Human)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | RPV339Hu01 | Recombinant Sorbitol Dehydrogenase (SDH) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | MAV339Hu01 | Monoclonal Antibody to Sorbitol Dehydrogenase (SDH) | WB; IHC; ICC; IP. |
PAV339Hu01 | Polyclonal Antibody to Sorbitol Dehydrogenase (SDH) | WB; IHC; ICC; IF. | |
Assay Kits | CLV339Hu01 | CLIA Kit for Sorbitol Dehydrogenase (SDH) | CLIA assay for Antigen Detection |
ELV339Hu01 | ELISA Kit for Sorbitol Dehydrogenase (SDH) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | RPV339Mu01 | Recombinant Sorbitol Dehydrogenase (SDH) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | MAV339Mu01 | Monoclonal Antibody to Sorbitol Dehydrogenase (SDH) | WB; IHC; ICC; IP. |
PAV339Mu01 | Polyclonal Antibody to Sorbitol Dehydrogenase (SDH) | WB; IHC; ICC; IF. | |
Assay Kits | CLV339Mu01 | CLIA Kit for Sorbitol Dehydrogenase (SDH) | CLIA assay for Antigen Detection |
ELV339Mu01 | ELISA Kit for Sorbitol Dehydrogenase (SDH) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | RPV339Ra01 | Recombinant Sorbitol Dehydrogenase (SDH) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | MAV339Ra01 | Monoclonal Antibody to Sorbitol Dehydrogenase (SDH) | WB; IHC; ICC; IP. |
PAV339Ra01 | Polyclonal Antibody to Sorbitol Dehydrogenase (SDH) | WB; IHC; ICC; IF. | |
Assay Kits | CLV339Ra01 | CLIA Kit for Sorbitol Dehydrogenase (SDH) | CLIA assay for Antigen Detection |
ELV339Ra01 | ELISA Kit for Sorbitol Dehydrogenase (SDH) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | RPV339Ca01 | Recombinant Sorbitol Dehydrogenase (SDH) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | MAV339Ca01 | Monoclonal Antibody to Sorbitol Dehydrogenase (SDH) | WB; IHC; ICC; IP. |
PAV339Ca01 | Polyclonal Antibody to Sorbitol Dehydrogenase (SDH) | WB; IHC; ICC; IF. | |
Assay Kits | CLV339Ca01 | CLIA Kit for Sorbitol Dehydrogenase (SDH) | CLIA assay for Antigen Detection |
ELV339Ca01 | ELISA Kit for Sorbitol Dehydrogenase (SDH) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | RPV339Po01 | Recombinant Sorbitol Dehydrogenase (SDH) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | MAV339Po01 | Monoclonal Antibody to Sorbitol Dehydrogenase (SDH) | WB; IHC; ICC; IP. |
PAV339Po01 | Polyclonal Antibody to Sorbitol Dehydrogenase (SDH) | WB; IHC; ICC; IF. | |
Assay Kits | CLV339Po01 | CLIA Kit for Sorbitol Dehydrogenase (SDH) | CLIA assay for Antigen Detection |
ELV339Po01 | ELISA Kit for Sorbitol Dehydrogenase (SDH) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | RPV339Bo01 | Recombinant Sorbitol Dehydrogenase (SDH) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | MAV339Bo01 | Monoclonal Antibody to Sorbitol Dehydrogenase (SDH) | WB; IHC; ICC; IP. |
PAV339Bo01 | Polyclonal Antibody to Sorbitol Dehydrogenase (SDH) | WB; IHC; ICC; IF. | |
Assay Kits | CLV339Bo01 | CLIA Kit for Sorbitol Dehydrogenase (SDH) | CLIA assay for Antigen Detection |
ELV339Bo01 | ELISA Kit for Sorbitol Dehydrogenase (SDH) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | RPV339Rb01 | Recombinant Sorbitol Dehydrogenase (SDH) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | MAV339Rb01 | Monoclonal Antibody to Sorbitol Dehydrogenase (SDH) | WB; IHC; ICC; IP. |
PAV339Rb01 | Polyclonal Antibody to Sorbitol Dehydrogenase (SDH) | WB; IHC; ICC; IF. | |
Assay Kits | CLV339Rb01 | CLIA Kit for Sorbitol Dehydrogenase (SDH) | CLIA assay for Antigen Detection |
ELV339Rb01 | ELISA Kit for Sorbitol Dehydrogenase (SDH) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | RPV339Mo01 | Recombinant Sorbitol Dehydrogenase (SDH) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | MAV339Mo01 | Monoclonal Antibody to Sorbitol Dehydrogenase (SDH) | WB; IHC; ICC; IP. |
PAV339Mo01 | Polyclonal Antibody to Sorbitol Dehydrogenase (SDH) | WB; IHC; ICC; IF. | |
Assay Kits | CLV339Mo01 | CLIA Kit for Sorbitol Dehydrogenase (SDH) | CLIA assay for Antigen Detection |
ELV339Mo01 | ELISA Kit for Sorbitol Dehydrogenase (SDH) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
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"Structural organization of the human sorbitol dehydrogenase gene (SORD)."
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Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
"Sorbitol dehydrogenase expression is regulated by androgens in the human prostate."
Oncol. Rep. 23:1233-1239(2010) [PubMed] [Europe PMC] [Abstract]
"ZAC1 is up-regulated by hypertonicity and decreases sorbitol dehydrogenase expression, allowing accumulation of sorbitol in kidney cells."
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J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
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