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Lumican (LUM)
Lumican (LUM)
LDC; SLRR2D; KSPG lumican; Keratan sulfate proteoglycan lumican
Lumican is a member of the small leucine-rich proteoglycan family that includes decorin, biglycan, fibromodulin, keratocan, epiphycan, and osteoglycin. The protein moiety binds collagen fibrils and the highly charged hydrophilic glycosaminoglycans regulate interfibrillar spacings.Lumican is the major keratan sulfate proteoglycan of the cornea but is also distributed in interstitial collagenous matrices throughout the body. Lumican may regulate collagen fibril organization and circumferential growth, corneal transparency, and epithelial cell migration and tissue repair. Lumican belongs to the family of small leucine-rich repeat proteoglycans. Recent studies have shown that lumican participates in the maintenance of tissue homeostasis and modulates cellular functions including cell proliferation, migration, and differentiation.
Organism species: Homo sapiens (Human)
Organism species: Mus musculus (Mouse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Lumican (LUM) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Lumican (LUM) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Lumican (LUM) WB; IHC; ICC; IP.
PV338Mu01
Polyclonal Antibody to Lumican (LUM) WB; IHC; ICC; IF.
LV338Mu71
Biotin Linked-Polyclonal Antibody to Lumican (LUM) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Lumican (LUM) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Lumican (LUM) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Lumican (LUM) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Lumican (LUM) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Lumican (LUM) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Lumican (LUM) CLIA assay for Antigen Detection
Organism species: Rattus norvegicus (Rat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Lumican (LUM) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Lumican (LUM) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Lumican (LUM) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Lumican (LUM) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Lumican (LUM) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Lumican (LUM) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Lumican (LUM) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Lumican (LUM) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Lumican (LUM) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Lumican (LUM) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Lumican (LUM) CLIA assay for Antigen Detection
Organism species: Canis familiaris; Canine (Dog)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Lumican (LUM) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Lumican (LUM) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Lumican (LUM) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Lumican (LUM) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Lumican (LUM) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Lumican (LUM) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Lumican (LUM) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Lumican (LUM) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Lumican (LUM) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Lumican (LUM) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Lumican (LUM) CLIA assay for Antigen Detection
Organism species: Sus scrofa; Porcine (Pig)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Lumican (LUM) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Lumican (LUM) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Lumican (LUM) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Lumican (LUM) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Lumican (LUM) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Lumican (LUM) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Lumican (LUM) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Lumican (LUM) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Lumican (LUM) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Lumican (LUM) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Lumican (LUM) CLIA assay for Antigen Detection
Organism species: Bos taurus; Bovine (Cattle)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Lumican (LUM) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Lumican (LUM) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Lumican (LUM) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Lumican (LUM) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Lumican (LUM) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Lumican (LUM) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Lumican (LUM) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Lumican (LUM) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Lumican (LUM) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Lumican (LUM) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Lumican (LUM) CLIA assay for Antigen Detection
Organism species: Rhesus monkey (Simian)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Lumican (LUM) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Lumican (LUM) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Lumican (LUM) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Lumican (LUM) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Lumican (LUM) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Lumican (LUM) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Lumican (LUM) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Lumican (LUM) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Lumican (LUM) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Lumican (LUM) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Lumican (LUM) CLIA assay for Antigen Detection
Organism species: Chicken (Gallus)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Lumican (LUM) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Lumican (LUM) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Lumican (LUM) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Lumican (LUM) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Lumican (LUM) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Lumican (LUM) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Lumican (LUM) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Lumican (LUM) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Lumican (LUM) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Lumican (LUM) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Lumican (LUM) CLIA assay for Antigen Detection
Organism species: Ovis aries; Ovine (Sheep)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Lumican (LUM) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Lumican (LUM) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Lumican (LUM) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Lumican (LUM) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Lumican (LUM) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Lumican (LUM) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Lumican (LUM) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Lumican (LUM) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Lumican (LUM) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Lumican (LUM) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Lumican (LUM) CLIA assay for Antigen Detection
Organism species: Oryctolagus cuniculus (Rabbit)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Lumican (LUM) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Lumican (LUM) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Lumican (LUM) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Lumican (LUM) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Lumican (LUM) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Lumican (LUM) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Lumican (LUM) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Lumican (LUM) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Lumican (LUM) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Lumican (LUM) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Lumican (LUM) CLIA assay for Antigen Detection
Organism species: Cavia (Guinea pig )
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Lumican (LUM) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Lumican (LUM) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Lumican (LUM) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Lumican (LUM) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Lumican (LUM) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Lumican (LUM) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Lumican (LUM) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Lumican (LUM) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Lumican (LUM) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Lumican (LUM) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Lumican (LUM) CLIA assay for Antigen Detection
Organism species: Equus caballus; Equine (Horse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Lumican (LUM) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Lumican (LUM) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Lumican (LUM) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Lumican (LUM) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Lumican (LUM) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Lumican (LUM) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Lumican (LUM) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Lumican (LUM) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Lumican (LUM) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Lumican (LUM) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Lumican (LUM) CLIA assay for Antigen Detection
Organism species: Capra hircus; Caprine (Goat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Lumican (LUM) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Lumican (LUM) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Lumican (LUM) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Lumican (LUM) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Lumican (LUM) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Lumican (LUM) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Lumican (LUM) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Lumican (LUM) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Lumican (LUM) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Lumican (LUM) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Lumican (LUM) CLIA assay for Antigen Detection
Organism species: Pan-species (General)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Lumican (LUM) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Lumican (LUM) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Lumican (LUM) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Lumican (LUM) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Lumican (LUM) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Lumican (LUM) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Lumican (LUM) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Lumican (LUM) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Lumican (LUM) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Lumican (LUM) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Lumican (LUM) CLIA assay for Antigen Detection
Reference
"The human lumican gene. Organization, chromosomal location, and expression in articular cartilage." J. Biol. Chem. 270:21942-21949(1995) [PubMed ] [Europe PMC ] [Abstract ]
"Primary structure of human lumican (keratan sulfate proteoglycan) and localization of the gene (LUM) to chromosome 12q21.3-q22." Genomics 27:481-488(1995) [PubMed ] [Europe PMC ] [Abstract ]
"Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed ] [Europe PMC ] [Abstract ]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." Genome Res. 14:2121-2127(2004) [PubMed ] [Europe PMC ] [Abstract ]
"Identification of tyrosine sulfation in extracellular leucine-rich repeat proteins using mass spectrometry." J. Biol. Chem. 279:26-33(2004) [PubMed ] [Europe PMC ] [Abstract ]
"Screening for N-glycosylated proteins by liquid chromatography mass spectrometry." Proteomics 4:454-465(2004) [PubMed ] [Europe PMC ] [Abstract ]
"Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry." J. Proteome Res. 4:2070-2080(2005) [PubMed ] [Europe PMC ] [Abstract ]
"Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry." J. Proteome Res. 8:651-661(2009) [PubMed ] [Europe PMC ] [Abstract ]
"An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome." J. Proteomics 96:253-262(2014) [PubMed ] [Europe PMC ] [Abstract ]
"Resequencing of 29 candidate genes in patients with familial and sporadic amyotrophic lateral sclerosis." Arch. Neurol. 68:587-593(2011) [PubMed ] [Europe PMC ] [Abstract ]
