Interleukin 3 Receptor Alpha (IL3Ra)
CD123; IL3R-A; IL3RY; IL3RAY; IL3R; IL3RAY; IL3RY; hIL-3Ra
interleukin-3 receptor is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5).
The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudoautosomal region on chromosomes X or Y.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV329Hu01 | Recombinant Interleukin 3 Receptor Alpha (IL3Ra) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV329Hu01 | Monoclonal Antibody to Interleukin 3 Receptor Alpha (IL3Ra) | WB; IHC; ICC; IP. |
| PAV329Hu01 | Polyclonal Antibody to Interleukin 3 Receptor Alpha (IL3Ra) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV329Hu01 | CLIA Kit for Interleukin 3 Receptor Alpha (IL3Ra) | CLIA assay for Antigen Detection |
| ELV329Hu01 | ELISA Kit for Interleukin 3 Receptor Alpha (IL3Ra) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV329Mu01 | Recombinant Interleukin 3 Receptor Alpha (IL3Ra) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV329Mu01 | Monoclonal Antibody to Interleukin 3 Receptor Alpha (IL3Ra) | WB; IHC; ICC; IP. |
| PAV329Mu01 | Polyclonal Antibody to Interleukin 3 Receptor Alpha (IL3Ra) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV329Mu01 | CLIA Kit for Interleukin 3 Receptor Alpha (IL3Ra) | CLIA assay for Antigen Detection |
| ELV329Mu01 | ELISA Kit for Interleukin 3 Receptor Alpha (IL3Ra) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV329Ra01 | Recombinant Interleukin 3 Receptor Alpha (IL3Ra) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV329Ra01 | Monoclonal Antibody to Interleukin 3 Receptor Alpha (IL3Ra) | WB; IHC; ICC; IP. |
| PAV329Ra01 | Polyclonal Antibody to Interleukin 3 Receptor Alpha (IL3Ra) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV329Ra01 | CLIA Kit for Interleukin 3 Receptor Alpha (IL3Ra) | CLIA assay for Antigen Detection |
| ELV329Ra01 | ELISA Kit for Interleukin 3 Receptor Alpha (IL3Ra) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV329Ca01 | Recombinant Interleukin 3 Receptor Alpha (IL3Ra) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV329Ca01 | Monoclonal Antibody to Interleukin 3 Receptor Alpha (IL3Ra) | WB; IHC; ICC; IP. |
| PAV329Ca01 | Polyclonal Antibody to Interleukin 3 Receptor Alpha (IL3Ra) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV329Ca01 | CLIA Kit for Interleukin 3 Receptor Alpha (IL3Ra) | CLIA assay for Antigen Detection |
| ELV329Ca01 | ELISA Kit for Interleukin 3 Receptor Alpha (IL3Ra) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV329Po01 | Recombinant Interleukin 3 Receptor Alpha (IL3Ra) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV329Po01 | Monoclonal Antibody to Interleukin 3 Receptor Alpha (IL3Ra) | WB; IHC; ICC; IP. |
| PAV329Po01 | Polyclonal Antibody to Interleukin 3 Receptor Alpha (IL3Ra) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV329Po01 | CLIA Kit for Interleukin 3 Receptor Alpha (IL3Ra) | CLIA assay for Antigen Detection |
| ELV329Po01 | ELISA Kit for Interleukin 3 Receptor Alpha (IL3Ra) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV329Bo01 | Recombinant Interleukin 3 Receptor Alpha (IL3Ra) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV329Bo01 | Monoclonal Antibody to Interleukin 3 Receptor Alpha (IL3Ra) | WB; IHC; ICC; IP. |
| PAV329Bo01 | Polyclonal Antibody to Interleukin 3 Receptor Alpha (IL3Ra) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV329Bo01 | CLIA Kit for Interleukin 3 Receptor Alpha (IL3Ra) | CLIA assay for Antigen Detection |
| ELV329Bo01 | ELISA Kit for Interleukin 3 Receptor Alpha (IL3Ra) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV329Rb01 | Recombinant Interleukin 3 Receptor Alpha (IL3Ra) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV329Rb01 | Monoclonal Antibody to Interleukin 3 Receptor Alpha (IL3Ra) | WB; IHC; ICC; IP. |
| PAV329Rb01 | Polyclonal Antibody to Interleukin 3 Receptor Alpha (IL3Ra) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV329Rb01 | CLIA Kit for Interleukin 3 Receptor Alpha (IL3Ra) | CLIA assay for Antigen Detection |
| ELV329Rb01 | ELISA Kit for Interleukin 3 Receptor Alpha (IL3Ra) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV329Mo01 | Recombinant Interleukin 3 Receptor Alpha (IL3Ra) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV329Mo01 | Monoclonal Antibody to Interleukin 3 Receptor Alpha (IL3Ra) | WB; IHC; ICC; IP. |
| PAV329Mo01 | Polyclonal Antibody to Interleukin 3 Receptor Alpha (IL3Ra) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV329Mo01 | CLIA Kit for Interleukin 3 Receptor Alpha (IL3Ra) | CLIA assay for Antigen Detection |
| ELV329Mo01 | ELISA Kit for Interleukin 3 Receptor Alpha (IL3Ra) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"Expression cloning of the human IL-3 receptor cDNA reveals a shared beta subunit for the human IL-3 and GM-CSF receptors."
Cell 66:1165-1174(1991) [PubMed] [Europe PMC] [Abstract]
"Structure of the gene encoding the alpha subunit of the human interleukin 3 receptor."
Biochem. Biophys. Res. Commun. 208:360-367(1995) [PubMed] [Europe PMC] [Abstract]
"A new isoform of IL-3 receptor alpha with novel differentiation activity and high affinity binding mode."
J. Biol. Chem. 284:5763-5773(2009) [PubMed] [Europe PMC] [Abstract]
"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
"The DNA sequence of the human X chromosome."
Nature 434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]