Prominin 1 (PROM1)
CD133; PROML1; Macular Dystrophy,Retinal 2; Stargardt Disease 4(Autosomal Dominant); Prominin-like protein 1; Antigen AC133
CD133 is a glycoprotein also known in humans and rodents as Prominin 1 (PROM1).It is the founding member of pentaspan transmembrane glycoproteins (5-transmembrane, 5-TM), which specifically localizes to cellular protrusions. CD133 is expressed in hematopoietic stem cells, endothelial progenitor cells, glioblastomas, neuronal and glial stem cells and some other cell types.
In contrast, AC133-1 was prominent in fetal brain and adult skeletal muscle and absent in fetal liver and kidney and in adult pancreas, kidney, bone marrow, hematopoietic stem cells, and placenta. RT-PCR and flow cytometric analysis revealed expression of AC133-2 in basal epidermal stem cells, and the expression was downregulated in cultured basal cells.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV318Hu01 | Recombinant Prominin 1 (PROM1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV318Hu01 | Monoclonal Antibody to Prominin 1 (PROM1) | WB; IHC; ICC; IP. |
| PAV318Hu01 | Polyclonal Antibody to Prominin 1 (PROM1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV318Hu01 | CLIA Kit for Prominin 1 (PROM1) | CLIA assay for Antigen Detection |
| ELV318Hu01 | ELISA Kit for Prominin 1 (PROM1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV318Mu01 | Recombinant Prominin 1 (PROM1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV318Mu01 | Monoclonal Antibody to Prominin 1 (PROM1) | WB; IHC; ICC; IP. |
| PAV318Mu01 | Polyclonal Antibody to Prominin 1 (PROM1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV318Mu01 | CLIA Kit for Prominin 1 (PROM1) | CLIA assay for Antigen Detection |
| ELV318Mu01 | ELISA Kit for Prominin 1 (PROM1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV318Ra01 | Recombinant Prominin 1 (PROM1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV318Ra01 | Monoclonal Antibody to Prominin 1 (PROM1) | WB; IHC; ICC; IP. |
| PAV318Ra01 | Polyclonal Antibody to Prominin 1 (PROM1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV318Ra01 | CLIA Kit for Prominin 1 (PROM1) | CLIA assay for Antigen Detection |
| ELV318Ra01 | ELISA Kit for Prominin 1 (PROM1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV318Ca01 | Recombinant Prominin 1 (PROM1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV318Ca01 | Monoclonal Antibody to Prominin 1 (PROM1) | WB; IHC; ICC; IP. |
| PAV318Ca01 | Polyclonal Antibody to Prominin 1 (PROM1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV318Ca01 | CLIA Kit for Prominin 1 (PROM1) | CLIA assay for Antigen Detection |
| ELV318Ca01 | ELISA Kit for Prominin 1 (PROM1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV318Po01 | Recombinant Prominin 1 (PROM1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV318Po01 | Monoclonal Antibody to Prominin 1 (PROM1) | WB; IHC; ICC; IP. |
| PAV318Po01 | Polyclonal Antibody to Prominin 1 (PROM1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV318Po01 | CLIA Kit for Prominin 1 (PROM1) | CLIA assay for Antigen Detection |
| ELV318Po01 | ELISA Kit for Prominin 1 (PROM1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV318Bo01 | Recombinant Prominin 1 (PROM1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV318Bo01 | Monoclonal Antibody to Prominin 1 (PROM1) | WB; IHC; ICC; IP. |
| PAV318Bo01 | Polyclonal Antibody to Prominin 1 (PROM1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV318Bo01 | CLIA Kit for Prominin 1 (PROM1) | CLIA assay for Antigen Detection |
| ELV318Bo01 | ELISA Kit for Prominin 1 (PROM1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV318Rb01 | Recombinant Prominin 1 (PROM1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV318Rb01 | Monoclonal Antibody to Prominin 1 (PROM1) | WB; IHC; ICC; IP. |
| PAV318Rb01 | Polyclonal Antibody to Prominin 1 (PROM1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV318Rb01 | CLIA Kit for Prominin 1 (PROM1) | CLIA assay for Antigen Detection |
| ELV318Rb01 | ELISA Kit for Prominin 1 (PROM1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV318Mo01 | Recombinant Prominin 1 (PROM1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV318Mo01 | Monoclonal Antibody to Prominin 1 (PROM1) | WB; IHC; ICC; IP. |
| PAV318Mo01 | Polyclonal Antibody to Prominin 1 (PROM1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV318Mo01 | CLIA Kit for Prominin 1 (PROM1) | CLIA assay for Antigen Detection |
| ELV318Mo01 | ELISA Kit for Prominin 1 (PROM1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
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"CD133 suppresses neuroblastoma cell differentiation via signal pathway modification."
Oncogene 30:97-105(2011) [PubMed] [Europe PMC] [Abstract]
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Hum. Mol. Genet. 9:27-34(2000) [PubMed] [Europe PMC] [Abstract]
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Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
"Post-translational regulation of CD133 by ATase1/ATase2-mediated lysine acetylation."
J. Mol. Biol. 426:2175-2182(2014) [PubMed] [Europe PMC] [Abstract]
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J. Clin. Invest. 118:2908-2916(2008) [PubMed] [Europe PMC] [Abstract]