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Cytohesin 1 (CYTH1)

CYT1; B2-1; SEC7; PSCD1; Pleckstrin Homology,Sec7 And Coiled-Coil Domains 1

Pleckstrin homology, Sec7 and coiled/coil domains 1 (PSCD1) is a member of the PSCD family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. The PSCD1 is highly expressed in natural killer and peripheral T cells, and regulates the adhesiveness of integrins at the plasma membrane of lymphocytes. PSCD1 protein is 83% homologous to PSCD2.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins V255Hu01 Recombinant Cytohesin 1 (CYTH1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Cytohesin 1 (CYTH1) Bioactivity
Antibodies NONE Monoclonal Antibody to Cytohesin 1 (CYTH1) WB; IHC; ICC; IP.
PV255Hu01 Polyclonal Antibody to Cytohesin 1 (CYTH1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Cytohesin 1 (CYTH1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Cytohesin 1 (CYTH1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Cytohesin 1 (CYTH1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Cytohesin 1 (CYTH1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Cytohesin 1 (CYTH1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Cytohesin 1 (CYTH1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Cytohesin 1 (CYTH1) CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Cytohesin 1 (CYTH1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Cytohesin 1 (CYTH1) Bioactivity
Antibodies NONE Monoclonal Antibody to Cytohesin 1 (CYTH1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Cytohesin 1 (CYTH1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Cytohesin 1 (CYTH1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Cytohesin 1 (CYTH1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Cytohesin 1 (CYTH1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Cytohesin 1 (CYTH1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Cytohesin 1 (CYTH1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Cytohesin 1 (CYTH1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Cytohesin 1 (CYTH1) CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Cytohesin 1 (CYTH1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Cytohesin 1 (CYTH1) Bioactivity
Antibodies NONE Monoclonal Antibody to Cytohesin 1 (CYTH1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Cytohesin 1 (CYTH1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Cytohesin 1 (CYTH1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Cytohesin 1 (CYTH1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Cytohesin 1 (CYTH1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Cytohesin 1 (CYTH1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Cytohesin 1 (CYTH1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Cytohesin 1 (CYTH1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Cytohesin 1 (CYTH1) CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Cytohesin 1 (CYTH1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Cytohesin 1 (CYTH1) Bioactivity
Antibodies NONE Monoclonal Antibody to Cytohesin 1 (CYTH1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Cytohesin 1 (CYTH1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Cytohesin 1 (CYTH1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Cytohesin 1 (CYTH1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Cytohesin 1 (CYTH1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Cytohesin 1 (CYTH1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Cytohesin 1 (CYTH1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Cytohesin 1 (CYTH1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Cytohesin 1 (CYTH1) CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Cytohesin 1 (CYTH1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Cytohesin 1 (CYTH1) Bioactivity
Antibodies NONE Monoclonal Antibody to Cytohesin 1 (CYTH1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Cytohesin 1 (CYTH1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Cytohesin 1 (CYTH1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Cytohesin 1 (CYTH1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Cytohesin 1 (CYTH1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Cytohesin 1 (CYTH1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Cytohesin 1 (CYTH1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Cytohesin 1 (CYTH1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Cytohesin 1 (CYTH1) CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Cytohesin 1 (CYTH1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Cytohesin 1 (CYTH1) Bioactivity
Antibodies NONE Monoclonal Antibody to Cytohesin 1 (CYTH1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Cytohesin 1 (CYTH1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Cytohesin 1 (CYTH1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Cytohesin 1 (CYTH1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Cytohesin 1 (CYTH1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Cytohesin 1 (CYTH1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Cytohesin 1 (CYTH1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Cytohesin 1 (CYTH1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Cytohesin 1 (CYTH1) CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Cytohesin 1 (CYTH1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Cytohesin 1 (CYTH1) Bioactivity
Antibodies NONE Monoclonal Antibody to Cytohesin 1 (CYTH1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Cytohesin 1 (CYTH1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Cytohesin 1 (CYTH1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Cytohesin 1 (CYTH1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Cytohesin 1 (CYTH1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Cytohesin 1 (CYTH1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Cytohesin 1 (CYTH1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Cytohesin 1 (CYTH1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Cytohesin 1 (CYTH1) CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Cytohesin 1 (CYTH1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Cytohesin 1 (CYTH1) Bioactivity
Antibodies NONE Monoclonal Antibody to Cytohesin 1 (CYTH1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Cytohesin 1 (CYTH1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Cytohesin 1 (CYTH1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Cytohesin 1 (CYTH1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Cytohesin 1 (CYTH1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Cytohesin 1 (CYTH1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Cytohesin 1 (CYTH1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Cytohesin 1 (CYTH1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Cytohesin 1 (CYTH1) CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Cytohesin 1 (CYTH1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Cytohesin 1 (CYTH1) Bioactivity
Antibodies NONE Monoclonal Antibody to Cytohesin 1 (CYTH1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Cytohesin 1 (CYTH1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Cytohesin 1 (CYTH1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Cytohesin 1 (CYTH1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Cytohesin 1 (CYTH1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Cytohesin 1 (CYTH1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Cytohesin 1 (CYTH1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Cytohesin 1 (CYTH1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Cytohesin 1 (CYTH1) CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Cytohesin 1 (CYTH1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Cytohesin 1 (CYTH1) Bioactivity
Antibodies NONE Monoclonal Antibody to Cytohesin 1 (CYTH1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Cytohesin 1 (CYTH1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Cytohesin 1 (CYTH1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Cytohesin 1 (CYTH1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Cytohesin 1 (CYTH1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Cytohesin 1 (CYTH1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Cytohesin 1 (CYTH1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Cytohesin 1 (CYTH1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Cytohesin 1 (CYTH1) CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Cytohesin 1 (CYTH1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Cytohesin 1 (CYTH1) Bioactivity
Antibodies NONE Monoclonal Antibody to Cytohesin 1 (CYTH1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Cytohesin 1 (CYTH1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Cytohesin 1 (CYTH1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Cytohesin 1 (CYTH1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Cytohesin 1 (CYTH1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Cytohesin 1 (CYTH1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Cytohesin 1 (CYTH1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Cytohesin 1 (CYTH1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Cytohesin 1 (CYTH1) CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Cytohesin 1 (CYTH1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Cytohesin 1 (CYTH1) Bioactivity
Antibodies NONE Monoclonal Antibody to Cytohesin 1 (CYTH1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Cytohesin 1 (CYTH1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Cytohesin 1 (CYTH1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Cytohesin 1 (CYTH1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Cytohesin 1 (CYTH1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Cytohesin 1 (CYTH1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Cytohesin 1 (CYTH1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Cytohesin 1 (CYTH1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Cytohesin 1 (CYTH1) CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Cytohesin 1 (CYTH1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Cytohesin 1 (CYTH1) Bioactivity
Antibodies NONE Monoclonal Antibody to Cytohesin 1 (CYTH1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Cytohesin 1 (CYTH1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Cytohesin 1 (CYTH1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Cytohesin 1 (CYTH1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Cytohesin 1 (CYTH1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Cytohesin 1 (CYTH1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Cytohesin 1 (CYTH1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Cytohesin 1 (CYTH1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Cytohesin 1 (CYTH1) CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Cytohesin 1 (CYTH1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Cytohesin 1 (CYTH1) Bioactivity
Antibodies NONE Monoclonal Antibody to Cytohesin 1 (CYTH1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Cytohesin 1 (CYTH1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Cytohesin 1 (CYTH1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Cytohesin 1 (CYTH1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Cytohesin 1 (CYTH1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Cytohesin 1 (CYTH1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Cytohesin 1 (CYTH1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Cytohesin 1 (CYTH1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Cytohesin 1 (CYTH1) CLIA assay for Antigen Detection

Reference

"Cloning and sequencing of a human cDNA from cytolytic NK/T cells with homology to yeast SEC7."
Biochim. Biophys. Acta 1132:75-78(1992) [PubMed] [Europe PMC] [Abstract]

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

"DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage."
Nature 440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Similarities in function and gene structure of cytohesin-4 and cytohesin-1, guanine nucleotide-exchange proteins for ADP-ribosylation factors."
J. Biol. Chem. 275:3221-3230(2000) [PubMed] [Europe PMC] [Abstract]

"Specific functional interaction of human cytohesin-1 and ADP-ribosylation factor domain protein (ARD1)."
J. Biol. Chem. 275:21331-21339(2000) [PubMed] [Europe PMC] [Abstract]

"Cybr, a cytokine-inducible protein that binds cytohesin-1 and regulates its activity."
Proc. Natl. Acad. Sci. U.S.A. 99:2625-2629(2002) [PubMed] [Europe PMC] [Abstract]

"The Arl4 family of small G proteins can recruit the cytohesin Arf6 exchange factors to the plasma membrane."
Curr. Biol. 17:711-716(2007) [PubMed] [Europe PMC] [Abstract]

"N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."
Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]

"Solution structure of the cytohesin-1 (B2-1) Sec7 domain and its interaction with the GTPase ADP ribosylation factor 1."
Proc. Natl. Acad. Sci. U.S.A. 95:7909-7914(1998) [PubMed] [Europe PMC] [Abstract]