Breast And Kidney Expressed Chemokine (BRAK)
CXCL14; SCYB14; BRAK; NJAC; Bolekine; Kec; MIP2-G; MIP2g; BMAC; KS1; Chemokine(C-X-C-Motif)ligand 14; Small Inducible Cytokine Subfamily B(Cys-X-Cys)Member 14
Chemokine (C-X-C motif) ligand 14 (CXCL14) is a small cytokine belonging to the CXC chemokine family that is also known as BRAK (for breast and kidney-expressed chemokine).Mature CXCL14 has many of the conserved features of the CXC chemokine subfamily but has some differences too, such as a shorter N-terminus and five extra amino acids in the region between its third and fourth cysteines.
CXCL14 is constitutively expressed at high levels in many normal tissues, where its cellular source is thought to be fibroblasts.However, it is reduced or absent from most cancer cells.This chemokine is chemotactic for monocytes and can activate these cells in the presence of an inflammatory mediator called prostaglandin-E2 (PGE2).
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV228Hu01 | Recombinant Breast And Kidney Expressed Chemokine (BRAK) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV228Hu01 | Monoclonal Antibody to Breast And Kidney Expressed Chemokine (BRAK) | WB; IHC; ICC; IP. |
| PAV228Hu01 | Polyclonal Antibody to Breast And Kidney Expressed Chemokine (BRAK) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV228Hu01 | CLIA Kit for Breast And Kidney Expressed Chemokine (BRAK) | CLIA assay for Antigen Detection |
| ELV228Hu01 | ELISA Kit for Breast And Kidney Expressed Chemokine (BRAK) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV228Mu01 | Recombinant Breast And Kidney Expressed Chemokine (BRAK) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV228Mu01 | Monoclonal Antibody to Breast And Kidney Expressed Chemokine (BRAK) | WB; IHC; ICC; IP. |
| PAV228Mu01 | Polyclonal Antibody to Breast And Kidney Expressed Chemokine (BRAK) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV228Mu01 | CLIA Kit for Breast And Kidney Expressed Chemokine (BRAK) | CLIA assay for Antigen Detection |
| ELV228Mu01 | ELISA Kit for Breast And Kidney Expressed Chemokine (BRAK) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV228Ra01 | Recombinant Breast And Kidney Expressed Chemokine (BRAK) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV228Ra01 | Monoclonal Antibody to Breast And Kidney Expressed Chemokine (BRAK) | WB; IHC; ICC; IP. |
| PAV228Ra01 | Polyclonal Antibody to Breast And Kidney Expressed Chemokine (BRAK) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV228Ra01 | CLIA Kit for Breast And Kidney Expressed Chemokine (BRAK) | CLIA assay for Antigen Detection |
| ELV228Ra01 | ELISA Kit for Breast And Kidney Expressed Chemokine (BRAK) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV228Ca01 | Recombinant Breast And Kidney Expressed Chemokine (BRAK) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV228Ca01 | Monoclonal Antibody to Breast And Kidney Expressed Chemokine (BRAK) | WB; IHC; ICC; IP. |
| PAV228Ca01 | Polyclonal Antibody to Breast And Kidney Expressed Chemokine (BRAK) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV228Ca01 | CLIA Kit for Breast And Kidney Expressed Chemokine (BRAK) | CLIA assay for Antigen Detection |
| ELV228Ca01 | ELISA Kit for Breast And Kidney Expressed Chemokine (BRAK) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV228Po01 | Recombinant Breast And Kidney Expressed Chemokine (BRAK) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV228Po01 | Monoclonal Antibody to Breast And Kidney Expressed Chemokine (BRAK) | WB; IHC; ICC; IP. |
| PAV228Po01 | Polyclonal Antibody to Breast And Kidney Expressed Chemokine (BRAK) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV228Po01 | CLIA Kit for Breast And Kidney Expressed Chemokine (BRAK) | CLIA assay for Antigen Detection |
| ELV228Po01 | ELISA Kit for Breast And Kidney Expressed Chemokine (BRAK) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV228Bo01 | Recombinant Breast And Kidney Expressed Chemokine (BRAK) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV228Bo01 | Monoclonal Antibody to Breast And Kidney Expressed Chemokine (BRAK) | WB; IHC; ICC; IP. |
| PAV228Bo01 | Polyclonal Antibody to Breast And Kidney Expressed Chemokine (BRAK) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV228Bo01 | CLIA Kit for Breast And Kidney Expressed Chemokine (BRAK) | CLIA assay for Antigen Detection |
| ELV228Bo01 | ELISA Kit for Breast And Kidney Expressed Chemokine (BRAK) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV228Rb01 | Recombinant Breast And Kidney Expressed Chemokine (BRAK) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV228Rb01 | Monoclonal Antibody to Breast And Kidney Expressed Chemokine (BRAK) | WB; IHC; ICC; IP. |
| PAV228Rb01 | Polyclonal Antibody to Breast And Kidney Expressed Chemokine (BRAK) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV228Rb01 | CLIA Kit for Breast And Kidney Expressed Chemokine (BRAK) | CLIA assay for Antigen Detection |
| ELV228Rb01 | ELISA Kit for Breast And Kidney Expressed Chemokine (BRAK) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV228Mo01 | Recombinant Breast And Kidney Expressed Chemokine (BRAK) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV228Mo01 | Monoclonal Antibody to Breast And Kidney Expressed Chemokine (BRAK) | WB; IHC; ICC; IP. |
| PAV228Mo01 | Polyclonal Antibody to Breast And Kidney Expressed Chemokine (BRAK) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV228Mo01 | CLIA Kit for Breast And Kidney Expressed Chemokine (BRAK) | CLIA assay for Antigen Detection |
| ELV228Mo01 | ELISA Kit for Breast And Kidney Expressed Chemokine (BRAK) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"In vivo expression of the novel CXC chemokine BRAK in normal and cancerous human tissue."
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Nature 431:268-274(2004) [PubMed] [Europe PMC] [Abstract]
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Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"Cloning of BRAK, a novel divergent CXC chemokine preferentially expressed in normal versus malignant cells."
Biochem. Biophys. Res. Commun. 255:703-706(1999) [PubMed] [Europe PMC] [Abstract]
"Structural determinants involved in the regulation of CXCL14/BRAK expression by the 26 S proteasome."
J. Mol. Biol. 363:813-822(2006) [PubMed] [Europe PMC] [Abstract]