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Ras GTPase Activating Protein 1 (RASA1)

Ras-GAP; RasGAP; CM-AVM; CMAVM; GAP; PKWS; RASA; P120GAP; RAS P21 Protein Activator 1; Capillary Malformation-Arteriovenous Malformation

RAS p21 protein activator 1 is a 120-kDa cytosolic human protein that provides two principal activities:Inactivation of Ras from its active GTP-bound form to its unactive GDP-bound form by enhancing the endogenous GTPase activity of Ras, via its C-terminal GAP domain Mitogenic signal transmission towards downstream interacting partners through its N-terminal SH2-SH3-SH2 domains. The protein is located in the cytoplasm and is part of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins V219Hu01 Recombinant Ras GTPase Activating Protein 1 (RASA1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Ras GTPase Activating Protein 1 (RASA1) Bioactivity
Antibodies NONE Monoclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) WB; IHC; ICC; IP.
PV219Hu01 Polyclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Ras GTPase Activating Protein 1 (RASA1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Ras GTPase Activating Protein 1 (RASA1) CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Ras GTPase Activating Protein 1 (RASA1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Ras GTPase Activating Protein 1 (RASA1) Bioactivity
Antibodies NONE Monoclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Ras GTPase Activating Protein 1 (RASA1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Ras GTPase Activating Protein 1 (RASA1) CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Ras GTPase Activating Protein 1 (RASA1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Ras GTPase Activating Protein 1 (RASA1) Bioactivity
Antibodies NONE Monoclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Ras GTPase Activating Protein 1 (RASA1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Ras GTPase Activating Protein 1 (RASA1) CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Ras GTPase Activating Protein 1 (RASA1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Ras GTPase Activating Protein 1 (RASA1) Bioactivity
Antibodies NONE Monoclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Ras GTPase Activating Protein 1 (RASA1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Ras GTPase Activating Protein 1 (RASA1) CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Ras GTPase Activating Protein 1 (RASA1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Ras GTPase Activating Protein 1 (RASA1) Bioactivity
Antibodies NONE Monoclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Ras GTPase Activating Protein 1 (RASA1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Ras GTPase Activating Protein 1 (RASA1) CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Ras GTPase Activating Protein 1 (RASA1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Ras GTPase Activating Protein 1 (RASA1) Bioactivity
Antibodies NONE Monoclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Ras GTPase Activating Protein 1 (RASA1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Ras GTPase Activating Protein 1 (RASA1) CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Ras GTPase Activating Protein 1 (RASA1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Ras GTPase Activating Protein 1 (RASA1) Bioactivity
Antibodies NONE Monoclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Ras GTPase Activating Protein 1 (RASA1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Ras GTPase Activating Protein 1 (RASA1) CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Ras GTPase Activating Protein 1 (RASA1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Ras GTPase Activating Protein 1 (RASA1) Bioactivity
Antibodies NONE Monoclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Ras GTPase Activating Protein 1 (RASA1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Ras GTPase Activating Protein 1 (RASA1) CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Ras GTPase Activating Protein 1 (RASA1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Ras GTPase Activating Protein 1 (RASA1) Bioactivity
Antibodies NONE Monoclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Ras GTPase Activating Protein 1 (RASA1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Ras GTPase Activating Protein 1 (RASA1) CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Ras GTPase Activating Protein 1 (RASA1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Ras GTPase Activating Protein 1 (RASA1) Bioactivity
Antibodies NONE Monoclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Ras GTPase Activating Protein 1 (RASA1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Ras GTPase Activating Protein 1 (RASA1) CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Ras GTPase Activating Protein 1 (RASA1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Ras GTPase Activating Protein 1 (RASA1) Bioactivity
Antibodies NONE Monoclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Ras GTPase Activating Protein 1 (RASA1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Ras GTPase Activating Protein 1 (RASA1) CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Ras GTPase Activating Protein 1 (RASA1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Ras GTPase Activating Protein 1 (RASA1) Bioactivity
Antibodies NONE Monoclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Ras GTPase Activating Protein 1 (RASA1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Ras GTPase Activating Protein 1 (RASA1) CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Ras GTPase Activating Protein 1 (RASA1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Ras GTPase Activating Protein 1 (RASA1) Bioactivity
Antibodies NONE Monoclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Ras GTPase Activating Protein 1 (RASA1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Ras GTPase Activating Protein 1 (RASA1) CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Ras GTPase Activating Protein 1 (RASA1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Ras GTPase Activating Protein 1 (RASA1) Bioactivity
Antibodies NONE Monoclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Ras GTPase Activating Protein 1 (RASA1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Ras GTPase Activating Protein 1 (RASA1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Ras GTPase Activating Protein 1 (RASA1) CLIA assay for Antigen Detection

Reference

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"N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."
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Submitted (MAY-2007) to the PDB data bank

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"Capillary malformation-arteriovenous malformation, a new clinical and genetic disorder caused by RASA1 mutations."
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"RASA1 mutations and associated phenotypes in 68 families with capillary malformation-arteriovenous malformation."
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