Potassium Chloride Cotransporters 2 (KCC2)
SLC12A5; Solute Carrier Family 12(Potassium/Chloride Transporters)Member 5; Chloride potassium symporter 5; K-Cl cotransporter 2; Neuronal K-Cl cotransporter
The cation-chloride cotransporter gene family includes that Na-Cl cotransporter (NCC), the Na-K-2Cl cotransporters (NKCCs), and the K-Cl cotransporters (KCCs). KCCs normally lower intracellular chloride concentrations below the electrochemical equilibrium potential. Depending on the chemical concentration gradients of potassium and chloride, KCC2 can operate as a net efflux or influx pathway (Hubner et al., 2001).
This potassium-chloride transporter is an integral membrane K-Cl cotransporter that can function in either a net efflux or influx pathway, depending on the chemical concentration gradients of potassium and chloride. The encoded protein can act as a homomultimer, or as a heteromultimer with other K-Cl cotransporters, to maintain chloride homeostasis in neurons.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV189Hu01 | Recombinant Potassium Chloride Cotransporters 2 (KCC2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV189Hu01 | Monoclonal Antibody to Potassium Chloride Cotransporters 2 (KCC2) | WB; IHC; ICC; IP. |
| PAV189Hu01 | Polyclonal Antibody to Potassium Chloride Cotransporters 2 (KCC2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV189Hu01 | CLIA Kit for Potassium Chloride Cotransporters 2 (KCC2) | CLIA assay for Antigen Detection |
| ELV189Hu01 | ELISA Kit for Potassium Chloride Cotransporters 2 (KCC2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV189Mu01 | Recombinant Potassium Chloride Cotransporters 2 (KCC2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV189Mu01 | Monoclonal Antibody to Potassium Chloride Cotransporters 2 (KCC2) | WB; IHC; ICC; IP. |
| PAV189Mu01 | Polyclonal Antibody to Potassium Chloride Cotransporters 2 (KCC2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV189Mu01 | CLIA Kit for Potassium Chloride Cotransporters 2 (KCC2) | CLIA assay for Antigen Detection |
| ELV189Mu01 | ELISA Kit for Potassium Chloride Cotransporters 2 (KCC2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV189Ra01 | Recombinant Potassium Chloride Cotransporters 2 (KCC2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV189Ra01 | Monoclonal Antibody to Potassium Chloride Cotransporters 2 (KCC2) | WB; IHC; ICC; IP. |
| PAV189Ra01 | Polyclonal Antibody to Potassium Chloride Cotransporters 2 (KCC2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV189Ra01 | CLIA Kit for Potassium Chloride Cotransporters 2 (KCC2) | CLIA assay for Antigen Detection |
| ELV189Ra01 | ELISA Kit for Potassium Chloride Cotransporters 2 (KCC2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV189Ca01 | Recombinant Potassium Chloride Cotransporters 2 (KCC2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV189Ca01 | Monoclonal Antibody to Potassium Chloride Cotransporters 2 (KCC2) | WB; IHC; ICC; IP. |
| PAV189Ca01 | Polyclonal Antibody to Potassium Chloride Cotransporters 2 (KCC2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV189Ca01 | CLIA Kit for Potassium Chloride Cotransporters 2 (KCC2) | CLIA assay for Antigen Detection |
| ELV189Ca01 | ELISA Kit for Potassium Chloride Cotransporters 2 (KCC2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV189Po01 | Recombinant Potassium Chloride Cotransporters 2 (KCC2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV189Po01 | Monoclonal Antibody to Potassium Chloride Cotransporters 2 (KCC2) | WB; IHC; ICC; IP. |
| PAV189Po01 | Polyclonal Antibody to Potassium Chloride Cotransporters 2 (KCC2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV189Po01 | CLIA Kit for Potassium Chloride Cotransporters 2 (KCC2) | CLIA assay for Antigen Detection |
| ELV189Po01 | ELISA Kit for Potassium Chloride Cotransporters 2 (KCC2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV189Bo01 | Recombinant Potassium Chloride Cotransporters 2 (KCC2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV189Bo01 | Monoclonal Antibody to Potassium Chloride Cotransporters 2 (KCC2) | WB; IHC; ICC; IP. |
| PAV189Bo01 | Polyclonal Antibody to Potassium Chloride Cotransporters 2 (KCC2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV189Bo01 | CLIA Kit for Potassium Chloride Cotransporters 2 (KCC2) | CLIA assay for Antigen Detection |
| ELV189Bo01 | ELISA Kit for Potassium Chloride Cotransporters 2 (KCC2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV189Rb01 | Recombinant Potassium Chloride Cotransporters 2 (KCC2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV189Rb01 | Monoclonal Antibody to Potassium Chloride Cotransporters 2 (KCC2) | WB; IHC; ICC; IP. |
| PAV189Rb01 | Polyclonal Antibody to Potassium Chloride Cotransporters 2 (KCC2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV189Rb01 | CLIA Kit for Potassium Chloride Cotransporters 2 (KCC2) | CLIA assay for Antigen Detection |
| ELV189Rb01 | ELISA Kit for Potassium Chloride Cotransporters 2 (KCC2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV189Mo01 | Recombinant Potassium Chloride Cotransporters 2 (KCC2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV189Mo01 | Monoclonal Antibody to Potassium Chloride Cotransporters 2 (KCC2) | WB; IHC; ICC; IP. |
| PAV189Mo01 | Polyclonal Antibody to Potassium Chloride Cotransporters 2 (KCC2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV189Mo01 | CLIA Kit for Potassium Chloride Cotransporters 2 (KCC2) | CLIA assay for Antigen Detection |
| ELV189Mo01 | ELISA Kit for Potassium Chloride Cotransporters 2 (KCC2) | Enzyme-linked immunosorbent assay for Antigen Detection |
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