Interleukin 18 Receptor 1 (IL18R1)

CDw218a; CD218a; IL18-R1; IL-1Rrp; IL1RRP; CD218 antigen-like family member A; IL1 receptor-related protein

SPN	V186
HGNC	5988
MGI	105383
PubMed	18774397
RGD	1308589
UniProt	Q13478
Wiki	IL18R1

interleukin-18 receptor 1 is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18), and is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. This gene along with four other members of the interleukin 1 receptor family, including IL1R2, IL1R1, ILRL2 (IL-1Rrp2), and IL1RL1 (T1/ST2), form a gene cluster on chromosome 2q.

Northern blot analysis revealed that IL1RRP is expressed in lung, leukocytes, spleen, liver, thymus, prostate, small intestine, colon, placenta, and heart, and is absent from brain, skeletal muscle, pancreas, and kidney.

Organism species: Homo sapiens (Human)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPV186Hu01	Recombinant Interleukin 18 Receptor 1 (IL18R1)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAV186Hu01	Monoclonal Antibody to Interleukin 18 Receptor 1 (IL18R1)	WB; IHC; ICC; IP.
Antibodies	PAV186Hu01	Polyclonal Antibody to Interleukin 18 Receptor 1 (IL18R1)	WB; IHC; ICC; IF.
Assay Kits	CLV186Hu01	CLIA Kit for Interleukin 18 Receptor 1 (IL18R1)	CLIA assay for Antigen Detection
Assay Kits	ELV186Hu01	ELISA Kit for Interleukin 18 Receptor 1 (IL18R1)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPV186Mu01	Recombinant Interleukin 18 Receptor 1 (IL18R1)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAV186Mu01	Monoclonal Antibody to Interleukin 18 Receptor 1 (IL18R1)	WB; IHC; ICC; IP.
Antibodies	PAV186Mu01	Polyclonal Antibody to Interleukin 18 Receptor 1 (IL18R1)	WB; IHC; ICC; IF.
Assay Kits	CLV186Mu01	CLIA Kit for Interleukin 18 Receptor 1 (IL18R1)	CLIA assay for Antigen Detection
Assay Kits	ELV186Mu01	ELISA Kit for Interleukin 18 Receptor 1 (IL18R1)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPV186Ra01	Recombinant Interleukin 18 Receptor 1 (IL18R1)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAV186Ra01	Monoclonal Antibody to Interleukin 18 Receptor 1 (IL18R1)	WB; IHC; ICC; IP.
Antibodies	PAV186Ra01	Polyclonal Antibody to Interleukin 18 Receptor 1 (IL18R1)	WB; IHC; ICC; IF.
Assay Kits	CLV186Ra01	CLIA Kit for Interleukin 18 Receptor 1 (IL18R1)	CLIA assay for Antigen Detection
Assay Kits	ELV186Ra01	ELISA Kit for Interleukin 18 Receptor 1 (IL18R1)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPV186Ca01	Recombinant Interleukin 18 Receptor 1 (IL18R1)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAV186Ca01	Monoclonal Antibody to Interleukin 18 Receptor 1 (IL18R1)	WB; IHC; ICC; IP.
Antibodies	PAV186Ca01	Polyclonal Antibody to Interleukin 18 Receptor 1 (IL18R1)	WB; IHC; ICC; IF.
Assay Kits	CLV186Ca01	CLIA Kit for Interleukin 18 Receptor 1 (IL18R1)	CLIA assay for Antigen Detection
Assay Kits	ELV186Ca01	ELISA Kit for Interleukin 18 Receptor 1 (IL18R1)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPV186Po01	Recombinant Interleukin 18 Receptor 1 (IL18R1)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAV186Po01	Monoclonal Antibody to Interleukin 18 Receptor 1 (IL18R1)	WB; IHC; ICC; IP.
Antibodies	PAV186Po01	Polyclonal Antibody to Interleukin 18 Receptor 1 (IL18R1)	WB; IHC; ICC; IF.
Assay Kits	CLV186Po01	CLIA Kit for Interleukin 18 Receptor 1 (IL18R1)	CLIA assay for Antigen Detection
Assay Kits	ELV186Po01	ELISA Kit for Interleukin 18 Receptor 1 (IL18R1)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPV186Bo01	Recombinant Interleukin 18 Receptor 1 (IL18R1)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAV186Bo01	Monoclonal Antibody to Interleukin 18 Receptor 1 (IL18R1)	WB; IHC; ICC; IP.
Antibodies	PAV186Bo01	Polyclonal Antibody to Interleukin 18 Receptor 1 (IL18R1)	WB; IHC; ICC; IF.
Assay Kits	CLV186Bo01	CLIA Kit for Interleukin 18 Receptor 1 (IL18R1)	CLIA assay for Antigen Detection
Assay Kits	ELV186Bo01	ELISA Kit for Interleukin 18 Receptor 1 (IL18R1)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPV186Rb01	Recombinant Interleukin 18 Receptor 1 (IL18R1)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAV186Rb01	Monoclonal Antibody to Interleukin 18 Receptor 1 (IL18R1)	WB; IHC; ICC; IP.
Antibodies	PAV186Rb01	Polyclonal Antibody to Interleukin 18 Receptor 1 (IL18R1)	WB; IHC; ICC; IF.
Assay Kits	CLV186Rb01	CLIA Kit for Interleukin 18 Receptor 1 (IL18R1)	CLIA assay for Antigen Detection
Assay Kits	ELV186Rb01	ELISA Kit for Interleukin 18 Receptor 1 (IL18R1)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPV186Mo01	Recombinant Interleukin 18 Receptor 1 (IL18R1)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAV186Mo01	Monoclonal Antibody to Interleukin 18 Receptor 1 (IL18R1)	WB; IHC; ICC; IP.
Antibodies	PAV186Mo01	Polyclonal Antibody to Interleukin 18 Receptor 1 (IL18R1)	WB; IHC; ICC; IF.
Assay Kits	CLV186Mo01	CLIA Kit for Interleukin 18 Receptor 1 (IL18R1)	CLIA assay for Antigen Detection
Assay Kits	ELV186Mo01	ELISA Kit for Interleukin 18 Receptor 1 (IL18R1)	Enzyme-linked immunosorbent assay for Antigen Detection

Reference

"IL-1Rrp is a novel receptor-like molecule similar to the type I interleukin-1 receptor and its homologues T1/ST2 and IL-1R AcP."
J. Biol. Chem. 271:3967-3970(1996) [PubMed] [Europe PMC] [Abstract]

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

"Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Purification and characterization of the human interleukin-18 receptor."
J. Biol. Chem. 272:25737-25742(1997) [PubMed] [Europe PMC] [Abstract]