Golgi Protein 73 (GP73)
GOLM1; GOLPH2; C9orf155; Golgi Membrane Protein 1; Golgi Phosphoprotein 2
Golgi protein-73 (GP73), a resident Golgi glycoprotein, is up-regulated in hepatocellular carcinoma (HCC). GP73 is a novel serum marker for HCC.
The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. 1 is a type II Golgi transmembrane protein. It processes protein synthesized in the rough endoplasmic reticulum and assists in the transport of protein cargo through the Golgi apparatus. The expression of this encoded protein has been observed to be upregulated in response to viral infection. Two alternatively spliced transcript variants encoding the same protein have been described for this gene.It is overexpressed in prostate cancer.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV170Hu01 | Recombinant Golgi Protein 73 (GP73) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV170Hu01 | Monoclonal Antibody to Golgi Protein 73 (GP73) | WB; IHC; ICC; IP. |
| PAV170Hu01 | Polyclonal Antibody to Golgi Protein 73 (GP73) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV170Hu01 | CLIA Kit for Golgi Protein 73 (GP73) | CLIA assay for Antigen Detection |
| ELV170Hu01 | ELISA Kit for Golgi Protein 73 (GP73) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV170Mu01 | Recombinant Golgi Protein 73 (GP73) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV170Mu01 | Monoclonal Antibody to Golgi Protein 73 (GP73) | WB; IHC; ICC; IP. |
| PAV170Mu01 | Polyclonal Antibody to Golgi Protein 73 (GP73) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV170Mu01 | CLIA Kit for Golgi Protein 73 (GP73) | CLIA assay for Antigen Detection |
| ELV170Mu01 | ELISA Kit for Golgi Protein 73 (GP73) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV170Ra01 | Recombinant Golgi Protein 73 (GP73) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV170Ra01 | Monoclonal Antibody to Golgi Protein 73 (GP73) | WB; IHC; ICC; IP. |
| PAV170Ra01 | Polyclonal Antibody to Golgi Protein 73 (GP73) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV170Ra01 | CLIA Kit for Golgi Protein 73 (GP73) | CLIA assay for Antigen Detection |
| ELV170Ra01 | ELISA Kit for Golgi Protein 73 (GP73) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV170Ca01 | Recombinant Golgi Protein 73 (GP73) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV170Ca01 | Monoclonal Antibody to Golgi Protein 73 (GP73) | WB; IHC; ICC; IP. |
| PAV170Ca01 | Polyclonal Antibody to Golgi Protein 73 (GP73) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV170Ca01 | CLIA Kit for Golgi Protein 73 (GP73) | CLIA assay for Antigen Detection |
| ELV170Ca01 | ELISA Kit for Golgi Protein 73 (GP73) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV170Po01 | Recombinant Golgi Protein 73 (GP73) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV170Po01 | Monoclonal Antibody to Golgi Protein 73 (GP73) | WB; IHC; ICC; IP. |
| PAV170Po01 | Polyclonal Antibody to Golgi Protein 73 (GP73) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV170Po01 | CLIA Kit for Golgi Protein 73 (GP73) | CLIA assay for Antigen Detection |
| ELV170Po01 | ELISA Kit for Golgi Protein 73 (GP73) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV170Bo01 | Recombinant Golgi Protein 73 (GP73) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV170Bo01 | Monoclonal Antibody to Golgi Protein 73 (GP73) | WB; IHC; ICC; IP. |
| PAV170Bo01 | Polyclonal Antibody to Golgi Protein 73 (GP73) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV170Bo01 | CLIA Kit for Golgi Protein 73 (GP73) | CLIA assay for Antigen Detection |
| ELV170Bo01 | ELISA Kit for Golgi Protein 73 (GP73) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV170Rb01 | Recombinant Golgi Protein 73 (GP73) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV170Rb01 | Monoclonal Antibody to Golgi Protein 73 (GP73) | WB; IHC; ICC; IP. |
| PAV170Rb01 | Polyclonal Antibody to Golgi Protein 73 (GP73) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV170Rb01 | CLIA Kit for Golgi Protein 73 (GP73) | CLIA assay for Antigen Detection |
| ELV170Rb01 | ELISA Kit for Golgi Protein 73 (GP73) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV170Mo01 | Recombinant Golgi Protein 73 (GP73) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV170Mo01 | Monoclonal Antibody to Golgi Protein 73 (GP73) | WB; IHC; ICC; IP. |
| PAV170Mo01 | Polyclonal Antibody to Golgi Protein 73 (GP73) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV170Mo01 | CLIA Kit for Golgi Protein 73 (GP73) | CLIA assay for Antigen Detection |
| ELV170Mo01 | ELISA Kit for Golgi Protein 73 (GP73) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"GP73, a novel Golgi-localized protein upregulated by viral infection."
Gene 249:53-65(2000) [PubMed] [Europe PMC] [Abstract]
"The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment."
Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
"Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries."
DNA Res. 12:117-126(2005) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"Cycling of early Golgi proteins via the cell surface and endosomes upon lumenal pH disruption."
Traffic 3:641-653(2002) [PubMed] [Europe PMC] [Abstract]
"Expression of GP73, a resident Golgi membrane protein, in viral and nonviral liver disease."
Hepatology 35:1431-1440(2002) [PubMed] [Europe PMC] [Abstract]
"Upregulation of the Golgi protein GP73 by adenovirus infection requires the E1A CtBP interaction domain."
Virology 301:236-246(2002) [PubMed] [Europe PMC] [Abstract]
"Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry."
J. Proteome Res. 4:2070-2080(2005) [PubMed] [Europe PMC] [Abstract]
"Identification of N-linked glycoproteins in human saliva by glycoprotein capture and mass spectrometry."
J. Proteome Res. 5:1493-1503(2006) [PubMed] [Europe PMC] [Abstract]
"A strategy for precise and large scale identification of core fucosylated glycoproteins."
Mol. Cell. Proteomics 8:913-923(2009) [PubMed] [Europe PMC] [Abstract]
"Dymeclin, the gene underlying Dyggve-Melchior-Clausen syndrome, encodes a protein integral to extracellular matrix and Golgi organization and is associated with protein secretion pathways critical in bone development."
Hum. Mutat. 32:231-239(2011) [PubMed] [Europe PMC] [Abstract]
"An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]