Cluster Of Differentiation 226 (CD226)
DNAM1; PTA1; TLiSA1; DNAX accessory molecule 1
CD226 is a ~65 kDa glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set and is encoded by a gene on human chromosome 18q22.3. CD226 mediates cellular adhesion to other cells bearing an unidentified ligand and cross-linking CD226 with antibodies causes cellular activation.
CD226 belongs to the immunoglobulin (Ig) superfamily and is expressed on the majority of natural killer (NK) cells, T cells, monocytes, and platelets. Through its interaction with various ligands, including LFA1, CD155 (PVR), and CD112 (PVRL2), CD226 plays an important role in T cell- and NK cell-mediated recognition and lysis of tumor cells.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV169Hu01 | Recombinant Cluster Of Differentiation 226 (CD226) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV169Hu01 | Monoclonal Antibody to Cluster Of Differentiation 226 (CD226) | WB; IHC; ICC; IP. |
| PAV169Hu01 | Polyclonal Antibody to Cluster Of Differentiation 226 (CD226) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV169Hu01 | CLIA Kit for Cluster Of Differentiation 226 (CD226) | CLIA assay for Antigen Detection |
| ELV169Hu01 | ELISA Kit for Cluster Of Differentiation 226 (CD226) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV169Mu01 | Recombinant Cluster Of Differentiation 226 (CD226) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV169Mu01 | Monoclonal Antibody to Cluster Of Differentiation 226 (CD226) | WB; IHC; ICC; IP. |
| PAV169Mu01 | Polyclonal Antibody to Cluster Of Differentiation 226 (CD226) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV169Mu01 | CLIA Kit for Cluster Of Differentiation 226 (CD226) | CLIA assay for Antigen Detection |
| ELV169Mu01 | ELISA Kit for Cluster Of Differentiation 226 (CD226) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV169Ra01 | Recombinant Cluster Of Differentiation 226 (CD226) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV169Ra01 | Monoclonal Antibody to Cluster Of Differentiation 226 (CD226) | WB; IHC; ICC; IP. |
| PAV169Ra01 | Polyclonal Antibody to Cluster Of Differentiation 226 (CD226) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV169Ra01 | CLIA Kit for Cluster Of Differentiation 226 (CD226) | CLIA assay for Antigen Detection |
| ELV169Ra01 | ELISA Kit for Cluster Of Differentiation 226 (CD226) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV169Ca01 | Recombinant Cluster Of Differentiation 226 (CD226) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV169Ca01 | Monoclonal Antibody to Cluster Of Differentiation 226 (CD226) | WB; IHC; ICC; IP. |
| PAV169Ca01 | Polyclonal Antibody to Cluster Of Differentiation 226 (CD226) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV169Ca01 | CLIA Kit for Cluster Of Differentiation 226 (CD226) | CLIA assay for Antigen Detection |
| ELV169Ca01 | ELISA Kit for Cluster Of Differentiation 226 (CD226) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV169Po01 | Recombinant Cluster Of Differentiation 226 (CD226) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV169Po01 | Monoclonal Antibody to Cluster Of Differentiation 226 (CD226) | WB; IHC; ICC; IP. |
| PAV169Po01 | Polyclonal Antibody to Cluster Of Differentiation 226 (CD226) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV169Po01 | CLIA Kit for Cluster Of Differentiation 226 (CD226) | CLIA assay for Antigen Detection |
| ELV169Po01 | ELISA Kit for Cluster Of Differentiation 226 (CD226) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV169Bo01 | Recombinant Cluster Of Differentiation 226 (CD226) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV169Bo01 | Monoclonal Antibody to Cluster Of Differentiation 226 (CD226) | WB; IHC; ICC; IP. |
| PAV169Bo01 | Polyclonal Antibody to Cluster Of Differentiation 226 (CD226) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV169Bo01 | CLIA Kit for Cluster Of Differentiation 226 (CD226) | CLIA assay for Antigen Detection |
| ELV169Bo01 | ELISA Kit for Cluster Of Differentiation 226 (CD226) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV169Rb01 | Recombinant Cluster Of Differentiation 226 (CD226) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV169Rb01 | Monoclonal Antibody to Cluster Of Differentiation 226 (CD226) | WB; IHC; ICC; IP. |
| PAV169Rb01 | Polyclonal Antibody to Cluster Of Differentiation 226 (CD226) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV169Rb01 | CLIA Kit for Cluster Of Differentiation 226 (CD226) | CLIA assay for Antigen Detection |
| ELV169Rb01 | ELISA Kit for Cluster Of Differentiation 226 (CD226) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV169Mo01 | Recombinant Cluster Of Differentiation 226 (CD226) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV169Mo01 | Monoclonal Antibody to Cluster Of Differentiation 226 (CD226) | WB; IHC; ICC; IP. |
| PAV169Mo01 | Polyclonal Antibody to Cluster Of Differentiation 226 (CD226) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV169Mo01 | CLIA Kit for Cluster Of Differentiation 226 (CD226) | CLIA assay for Antigen Detection |
| ELV169Mo01 | ELISA Kit for Cluster Of Differentiation 226 (CD226) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
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Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
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Int. Immunol. 16:533-538(2004) [PubMed] [Europe PMC] [Abstract]
"PVR (CD155) and Nectin-2 (CD112) as ligands of the human DNAM-1 (CD226) activating receptor: involvement in tumor cell lysis."
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