Call Now

Cluster Of Differentiation (CD163)

M130; MM130; Scavenger receptor cysteine-rich type 1 protein M130; Hemoglobin scavenger receptor

CD163, a hemoglobin scavenger receptor, is expressed in monocytes and macrophages.Acute phase-regulated receptor involved in clearance and endocytosis of hemoglobin/haptoglobin c by macrophages and may thereby protect tissues from free hemoglobin-mediated oxidative damage.

CD163 may play a role in the uptake and recycling of iron, via endocytosis of hemoglobin/haptoglobin and subsequent breakdown of heme. It binds hemoglobin/haptoglobin complexes in a calcium-dependent and pH-dependent manner. It exhibits a higher affinity for complexes of hemoglobin and multimeric haptoglobin of HP*1F phenotype than for complexes of hemoglobin and dimeric haptoglobin of HP*1S phenotype.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins V113Hu01 Recombinant Cluster Of Differentiation (CD163) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Cluster Of Differentiation (CD163) Bioactivity
Antibodies MV113Hu21 Monoclonal Antibody to Cluster Of Differentiation (CD163) WB; IHC; ICC; IP.
PV113Hu01 Polyclonal Antibody to Cluster Of Differentiation (CD163) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Cluster Of Differentiation (CD163) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Cluster Of Differentiation (CD163) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Cluster Of Differentiation (CD163) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Cluster Of Differentiation (CD163) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Cluster Of Differentiation (CD163) Flow Cytometry;ICC/IF
Assay Kits KEV113Hu ELISA Kit for Cluster Of Differentiation (CD163) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Cluster Of Differentiation (CD163) CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins V113Mu02 Recombinant Cluster Of Differentiation (CD163) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Cluster Of Differentiation (CD163) Bioactivity
Antibodies NONE Monoclonal Antibody to Cluster Of Differentiation (CD163) WB; IHC; ICC; IP.
PV113Mu01 Polyclonal Antibody to Cluster Of Differentiation (CD163) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Cluster Of Differentiation (CD163) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Cluster Of Differentiation (CD163) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Cluster Of Differentiation (CD163) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Cluster Of Differentiation (CD163) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Cluster Of Differentiation (CD163) Flow Cytometry;ICC/IF
Assay Kits KEV113Mu ELISA Kit for Cluster Of Differentiation (CD163) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Cluster Of Differentiation (CD163) CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Cluster Of Differentiation (CD163) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Cluster Of Differentiation (CD163) Bioactivity
Antibodies MV113Ra21 Monoclonal Antibody to Cluster Of Differentiation (CD163) WB; IHC; ICC; IP.
PV113Ra01 Polyclonal Antibody to Cluster Of Differentiation (CD163) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Cluster Of Differentiation (CD163) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Cluster Of Differentiation (CD163) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Cluster Of Differentiation (CD163) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Cluster Of Differentiation (CD163) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Cluster Of Differentiation (CD163) Flow Cytometry;ICC/IF
Assay Kits KEV113Ra ELISA Kit for Cluster Of Differentiation (CD163) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Cluster Of Differentiation (CD163) CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Cluster Of Differentiation (CD163) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Cluster Of Differentiation (CD163) Bioactivity
Antibodies NONE Monoclonal Antibody to Cluster Of Differentiation (CD163) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Cluster Of Differentiation (CD163) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Cluster Of Differentiation (CD163) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Cluster Of Differentiation (CD163) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Cluster Of Differentiation (CD163) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Cluster Of Differentiation (CD163) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Cluster Of Differentiation (CD163) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Cluster Of Differentiation (CD163) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Cluster Of Differentiation (CD163) CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Cluster Of Differentiation (CD163) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Cluster Of Differentiation (CD163) Bioactivity
Antibodies NONE Monoclonal Antibody to Cluster Of Differentiation (CD163) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Cluster Of Differentiation (CD163) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Cluster Of Differentiation (CD163) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Cluster Of Differentiation (CD163) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Cluster Of Differentiation (CD163) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Cluster Of Differentiation (CD163) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Cluster Of Differentiation (CD163) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Cluster Of Differentiation (CD163) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Cluster Of Differentiation (CD163) CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Cluster Of Differentiation (CD163) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Cluster Of Differentiation (CD163) Bioactivity
Antibodies NONE Monoclonal Antibody to Cluster Of Differentiation (CD163) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Cluster Of Differentiation (CD163) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Cluster Of Differentiation (CD163) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Cluster Of Differentiation (CD163) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Cluster Of Differentiation (CD163) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Cluster Of Differentiation (CD163) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Cluster Of Differentiation (CD163) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Cluster Of Differentiation (CD163) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Cluster Of Differentiation (CD163) CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Cluster Of Differentiation (CD163) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Cluster Of Differentiation (CD163) Bioactivity
Antibodies NONE Monoclonal Antibody to Cluster Of Differentiation (CD163) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Cluster Of Differentiation (CD163) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Cluster Of Differentiation (CD163) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Cluster Of Differentiation (CD163) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Cluster Of Differentiation (CD163) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Cluster Of Differentiation (CD163) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Cluster Of Differentiation (CD163) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Cluster Of Differentiation (CD163) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Cluster Of Differentiation (CD163) CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Cluster Of Differentiation (CD163) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Cluster Of Differentiation (CD163) Bioactivity
Antibodies NONE Monoclonal Antibody to Cluster Of Differentiation (CD163) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Cluster Of Differentiation (CD163) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Cluster Of Differentiation (CD163) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Cluster Of Differentiation (CD163) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Cluster Of Differentiation (CD163) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Cluster Of Differentiation (CD163) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Cluster Of Differentiation (CD163) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Cluster Of Differentiation (CD163) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Cluster Of Differentiation (CD163) CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Cluster Of Differentiation (CD163) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Cluster Of Differentiation (CD163) Bioactivity
Antibodies NONE Monoclonal Antibody to Cluster Of Differentiation (CD163) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Cluster Of Differentiation (CD163) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Cluster Of Differentiation (CD163) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Cluster Of Differentiation (CD163) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Cluster Of Differentiation (CD163) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Cluster Of Differentiation (CD163) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Cluster Of Differentiation (CD163) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Cluster Of Differentiation (CD163) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Cluster Of Differentiation (CD163) CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Cluster Of Differentiation (CD163) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Cluster Of Differentiation (CD163) Bioactivity
Antibodies NONE Monoclonal Antibody to Cluster Of Differentiation (CD163) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Cluster Of Differentiation (CD163) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Cluster Of Differentiation (CD163) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Cluster Of Differentiation (CD163) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Cluster Of Differentiation (CD163) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Cluster Of Differentiation (CD163) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Cluster Of Differentiation (CD163) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Cluster Of Differentiation (CD163) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Cluster Of Differentiation (CD163) CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Cluster Of Differentiation (CD163) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Cluster Of Differentiation (CD163) Bioactivity
Antibodies NONE Monoclonal Antibody to Cluster Of Differentiation (CD163) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Cluster Of Differentiation (CD163) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Cluster Of Differentiation (CD163) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Cluster Of Differentiation (CD163) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Cluster Of Differentiation (CD163) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Cluster Of Differentiation (CD163) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Cluster Of Differentiation (CD163) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Cluster Of Differentiation (CD163) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Cluster Of Differentiation (CD163) CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Cluster Of Differentiation (CD163) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Cluster Of Differentiation (CD163) Bioactivity
Antibodies NONE Monoclonal Antibody to Cluster Of Differentiation (CD163) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Cluster Of Differentiation (CD163) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Cluster Of Differentiation (CD163) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Cluster Of Differentiation (CD163) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Cluster Of Differentiation (CD163) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Cluster Of Differentiation (CD163) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Cluster Of Differentiation (CD163) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Cluster Of Differentiation (CD163) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Cluster Of Differentiation (CD163) CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Cluster Of Differentiation (CD163) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Cluster Of Differentiation (CD163) Bioactivity
Antibodies NONE Monoclonal Antibody to Cluster Of Differentiation (CD163) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Cluster Of Differentiation (CD163) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Cluster Of Differentiation (CD163) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Cluster Of Differentiation (CD163) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Cluster Of Differentiation (CD163) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Cluster Of Differentiation (CD163) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Cluster Of Differentiation (CD163) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Cluster Of Differentiation (CD163) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Cluster Of Differentiation (CD163) CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Cluster Of Differentiation (CD163) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Cluster Of Differentiation (CD163) Bioactivity
Antibodies NONE Monoclonal Antibody to Cluster Of Differentiation (CD163) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Cluster Of Differentiation (CD163) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Cluster Of Differentiation (CD163) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Cluster Of Differentiation (CD163) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Cluster Of Differentiation (CD163) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Cluster Of Differentiation (CD163) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Cluster Of Differentiation (CD163) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Cluster Of Differentiation (CD163) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Cluster Of Differentiation (CD163) CLIA assay for Antigen Detection

Reference

"A new macrophage differentiation antigen which is a member of the scavenger receptor superfamily."
Eur. J. Immunol. 23:2320-2325(1993) [PubMed] [Europe PMC] [Abstract]

"Genomic organization and chromosomal localization of the human CD163 (M130) gene: a member of the scavenger receptor cysteine-rich superfamily."
Biochem. Biophys. Res. Commun. 260:466-474(1999) [PubMed] [Europe PMC] [Abstract]

"The finished DNA sequence of human chromosome 12."
Nature 440:346-351(2006) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Shedding of CD163, a novel regulatory mechanism for a member of the scavenger receptor cysteine-rich family."
Biochem. Biophys. Res. Commun. 256:110-113(1999) [PubMed] [Europe PMC] [Abstract]

"Regulation of CD 163 on human macrophages: cross-linking of CD163 induces signaling and activation."
J. Leukoc. Biol. 66:858-866(1999) [PubMed] [Europe PMC] [Abstract]

"Regulation of scavenger receptor CD163 expression in human monocytes and macrophages by pro- and antiinflammatory stimuli."
J. Leukoc. Biol. 67:97-103(2000) [PubMed] [Europe PMC] [Abstract]

"Interaction of CD163 with the regulatory subunit of casein kinase II (CKII) and dependence of CD163 signaling on CKII and protein kinase C."
Eur. J. Immunol. 31:999-1009(2001) [PubMed] [Europe PMC] [Abstract]

"Identification of the haemoglobin scavenger receptor."
Nature 409:198-201(2001) [PubMed] [Europe PMC] [Abstract]

"Elevated levels of soluble CD163 in sera and fluids from rheumatoid arthritis patients and inhibition of the shedding of CD163 by TIMP-3."
Clin. Exp. Immunol. 130:156-161(2002) [PubMed] [Europe PMC] [Abstract]

"Only the soluble form of the scavenger receptor CD163 acts inhibitory on phorbol ester-activated T-lymphocytes, whereas membrane-bound protein has no effect."
FEBS Lett. 526:93-96(2002) [PubMed] [Europe PMC] [Abstract]

"Endotoxin induces rapid metalloproteinase-mediated shedding followed by up-regulation of the monocyte hemoglobin scavenger receptor CD163."
J. Leukoc. Biol. 72:711-717(2002) [PubMed] [Europe PMC] [Abstract]

"CD163: a regulated hemoglobin scavenger receptor with a role in the anti-inflammatory response."
Ann. Med. 36:347-354(2004) [PubMed] [Europe PMC] [Abstract]

"Molecular characterization of the haptoglobin.hemoglobin receptor CD163. Ligand binding properties of the scavenger receptor cysteine-rich domain region."
J. Biol. Chem. 279:51561-51567(2004) [PubMed] [Europe PMC] [Abstract]

"Cross-linking of FcgammaR triggers shedding of the hemoglobin-haptoglobin scavenger receptor CD163."
J. Leukoc. Biol. 76:271-277(2004) [PubMed] [Europe PMC] [Abstract]

"Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry."
J. Proteome Res. 4:2070-2080(2005) [PubMed] [Europe PMC] [Abstract]

"The macrophage scavenger receptor CD163: endocytic properties of cytoplasmic tail variants."
J. Leukoc. Biol. 79:837-845(2006) [PubMed] [Europe PMC] [Abstract]

"Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."
J. Proteome Res. 8:651-661(2009) [PubMed] [Europe PMC] [Abstract]

"A strategy for precise and large scale identification of core fucosylated glycoproteins."
Mol. Cell. Proteomics 8:913-923(2009) [PubMed] [Europe PMC] [Abstract]

"An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]