Glutamate Receptor Interacting Protein 1 (GRIP1)
In situ hybridization of embryonic day 17 (E17) rat embryos showed that Grip1 is expressed relatively homogeneously and strongly throughout most regions of the nervous system. Grip1 was expressed at very low levels in many nonneuronal tissues of E17 rat, with the highest levels found in nasal cavities and major blood vessels. Coimmunoprecipitation analysis demonstrated that Grip1 and Efnb1 interact in E14 mouse embryos.
Bruckner et al. (1999) found that GRIP1 is recruited into rafts through association with EFNB1. In addition, a GRIP1-associated serine/threonine kinase activity was recruited into EFNB1/GRIP1 complexes. Bruckner et al. (1999) suggested that GRIP proteins provide a scaffold for the assembly of a multiprotein signaling complex downstream of ephrin B ligands.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV086Hu01 | Recombinant Glutamate Receptor Interacting Protein 1 (GRIP1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV086Hu01 | Monoclonal Antibody to Glutamate Receptor Interacting Protein 1 (GRIP1) | WB; IHC; ICC; IP. |
| PAV086Hu01 | Polyclonal Antibody to Glutamate Receptor Interacting Protein 1 (GRIP1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV086Hu01 | CLIA Kit for Glutamate Receptor Interacting Protein 1 (GRIP1) | CLIA assay for Antigen Detection |
| ELV086Hu01 | ELISA Kit for Glutamate Receptor Interacting Protein 1 (GRIP1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV086Mu01 | Recombinant Glutamate Receptor Interacting Protein 1 (GRIP1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV086Mu01 | Monoclonal Antibody to Glutamate Receptor Interacting Protein 1 (GRIP1) | WB; IHC; ICC; IP. |
| PAV086Mu01 | Polyclonal Antibody to Glutamate Receptor Interacting Protein 1 (GRIP1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV086Mu01 | CLIA Kit for Glutamate Receptor Interacting Protein 1 (GRIP1) | CLIA assay for Antigen Detection |
| ELV086Mu01 | ELISA Kit for Glutamate Receptor Interacting Protein 1 (GRIP1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV086Ra01 | Recombinant Glutamate Receptor Interacting Protein 1 (GRIP1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV086Ra01 | Monoclonal Antibody to Glutamate Receptor Interacting Protein 1 (GRIP1) | WB; IHC; ICC; IP. |
| PAV086Ra01 | Polyclonal Antibody to Glutamate Receptor Interacting Protein 1 (GRIP1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV086Ra01 | CLIA Kit for Glutamate Receptor Interacting Protein 1 (GRIP1) | CLIA assay for Antigen Detection |
| ELV086Ra01 | ELISA Kit for Glutamate Receptor Interacting Protein 1 (GRIP1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV086Ca01 | Recombinant Glutamate Receptor Interacting Protein 1 (GRIP1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV086Ca01 | Monoclonal Antibody to Glutamate Receptor Interacting Protein 1 (GRIP1) | WB; IHC; ICC; IP. |
| PAV086Ca01 | Polyclonal Antibody to Glutamate Receptor Interacting Protein 1 (GRIP1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV086Ca01 | CLIA Kit for Glutamate Receptor Interacting Protein 1 (GRIP1) | CLIA assay for Antigen Detection |
| ELV086Ca01 | ELISA Kit for Glutamate Receptor Interacting Protein 1 (GRIP1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV086Po01 | Recombinant Glutamate Receptor Interacting Protein 1 (GRIP1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV086Po01 | Monoclonal Antibody to Glutamate Receptor Interacting Protein 1 (GRIP1) | WB; IHC; ICC; IP. |
| PAV086Po01 | Polyclonal Antibody to Glutamate Receptor Interacting Protein 1 (GRIP1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV086Po01 | CLIA Kit for Glutamate Receptor Interacting Protein 1 (GRIP1) | CLIA assay for Antigen Detection |
| ELV086Po01 | ELISA Kit for Glutamate Receptor Interacting Protein 1 (GRIP1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV086Bo01 | Recombinant Glutamate Receptor Interacting Protein 1 (GRIP1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV086Bo01 | Monoclonal Antibody to Glutamate Receptor Interacting Protein 1 (GRIP1) | WB; IHC; ICC; IP. |
| PAV086Bo01 | Polyclonal Antibody to Glutamate Receptor Interacting Protein 1 (GRIP1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV086Bo01 | CLIA Kit for Glutamate Receptor Interacting Protein 1 (GRIP1) | CLIA assay for Antigen Detection |
| ELV086Bo01 | ELISA Kit for Glutamate Receptor Interacting Protein 1 (GRIP1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV086Rb01 | Recombinant Glutamate Receptor Interacting Protein 1 (GRIP1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV086Rb01 | Monoclonal Antibody to Glutamate Receptor Interacting Protein 1 (GRIP1) | WB; IHC; ICC; IP. |
| PAV086Rb01 | Polyclonal Antibody to Glutamate Receptor Interacting Protein 1 (GRIP1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV086Rb01 | CLIA Kit for Glutamate Receptor Interacting Protein 1 (GRIP1) | CLIA assay for Antigen Detection |
| ELV086Rb01 | ELISA Kit for Glutamate Receptor Interacting Protein 1 (GRIP1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV086Mo01 | Recombinant Glutamate Receptor Interacting Protein 1 (GRIP1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV086Mo01 | Monoclonal Antibody to Glutamate Receptor Interacting Protein 1 (GRIP1) | WB; IHC; ICC; IP. |
| PAV086Mo01 | Polyclonal Antibody to Glutamate Receptor Interacting Protein 1 (GRIP1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV086Mo01 | CLIA Kit for Glutamate Receptor Interacting Protein 1 (GRIP1) | CLIA assay for Antigen Detection |
| ELV086Mo01 | ELISA Kit for Glutamate Receptor Interacting Protein 1 (GRIP1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"The finished DNA sequence of human chromosome 12."
Nature 440:346-351(2006) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"EphrinB ligands recruit GRIP family PDZ adaptor proteins into raft membrane microdomains."
Neuron 22:511-524(1999) [PubMed] [Europe PMC] [Abstract]
"The carboxyl terminus of the prolactin-releasing peptide receptor interacts with PDZ domain proteins involved in alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor clustering."
Mol. Pharmacol. 60:916-923(2001) [PubMed] [Europe PMC] [Abstract]
"Mutations in GRIP1 cause Fraser syndrome."
J. Med. Genet. 49:303-306(2012) [PubMed] [Europe PMC] [Abstract]
"The methyltransferase WBSCR22/Merm1 enhances glucocorticoid receptor function and is regulated in lung inflammation and cancer."
J. Biol. Chem. 289:8931-8946(2014) [PubMed] [Europe PMC] [Abstract]