Interferon Regulatory Factor 4 (IRF4)

LSIRF; MUM1; NF-EM5; Lymphocyte-specific interferon regulatory factor; Multiple myeloma oncogene 1

SPN	V084
HGNC	6119
MGI	1096873
PubMed	24591370
RGD	1308050
UniProt	Q15306
Wiki	IRF4

By fluorescence and confocal microscopy, Negishi et al. (2005) demonstrated that IRF4 interacted with MYD88 in the cytoplasm of human embryonic kidney cells. Mutation and coimmunoprecipitation analysis showed that IRF4 interacted with the TIR/IL1 region of MYD88.

IRF4 inhibited interaction of MYD88 with IRF5, which interacts with the same central region of MYD88 as IRF4, but it did not block interaction of MYD88 with IRF7 , which binds to the N terminus. IRF5-dependent gene induction was inhibited by IRF4, and IRF4-deficient macrophages were hyperresponsive to Toll-like receptor (TLR) stimuli. Negishi et al. (2005) concluded that IRF4 negatively regulates TLR signaling by selectively competing with IRF5.

Organism species: Homo sapiens (Human)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Interferon Regulatory Factor 4 (IRF4)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Interferon Regulatory Factor 4 (IRF4)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Interferon Regulatory Factor 4 (IRF4)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Interferon Regulatory Factor 4 (IRF4)	CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Interferon Regulatory Factor 4 (IRF4)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Interferon Regulatory Factor 4 (IRF4)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	WB; IHC; ICC; IP.
	PV084Mu01	Polyclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Interferon Regulatory Factor 4 (IRF4)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Interferon Regulatory Factor 4 (IRF4)	CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	V084Ra01	Recombinant Interferon Regulatory Factor 4 (IRF4)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Interferon Regulatory Factor 4 (IRF4)	Bioactivity
Antibodies	MV084Ra21	Monoclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	WB; IHC; ICC; IP.
	PV084Ra01	Polyclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Interferon Regulatory Factor 4 (IRF4)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Interferon Regulatory Factor 4 (IRF4)	CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Interferon Regulatory Factor 4 (IRF4)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Interferon Regulatory Factor 4 (IRF4)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Interferon Regulatory Factor 4 (IRF4)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Interferon Regulatory Factor 4 (IRF4)	CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Interferon Regulatory Factor 4 (IRF4)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Interferon Regulatory Factor 4 (IRF4)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Interferon Regulatory Factor 4 (IRF4)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Interferon Regulatory Factor 4 (IRF4)	CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Interferon Regulatory Factor 4 (IRF4)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Interferon Regulatory Factor 4 (IRF4)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Interferon Regulatory Factor 4 (IRF4)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Interferon Regulatory Factor 4 (IRF4)	CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Interferon Regulatory Factor 4 (IRF4)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Interferon Regulatory Factor 4 (IRF4)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Interferon Regulatory Factor 4 (IRF4)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Interferon Regulatory Factor 4 (IRF4)	CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Interferon Regulatory Factor 4 (IRF4)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Interferon Regulatory Factor 4 (IRF4)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Interferon Regulatory Factor 4 (IRF4)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Interferon Regulatory Factor 4 (IRF4)	CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Interferon Regulatory Factor 4 (IRF4)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Interferon Regulatory Factor 4 (IRF4)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Interferon Regulatory Factor 4 (IRF4)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Interferon Regulatory Factor 4 (IRF4)	CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Interferon Regulatory Factor 4 (IRF4)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Interferon Regulatory Factor 4 (IRF4)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Interferon Regulatory Factor 4 (IRF4)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Interferon Regulatory Factor 4 (IRF4)	CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Interferon Regulatory Factor 4 (IRF4)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Interferon Regulatory Factor 4 (IRF4)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Interferon Regulatory Factor 4 (IRF4)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Interferon Regulatory Factor 4 (IRF4)	CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Interferon Regulatory Factor 4 (IRF4)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Interferon Regulatory Factor 4 (IRF4)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Interferon Regulatory Factor 4 (IRF4)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Interferon Regulatory Factor 4 (IRF4)	CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Interferon Regulatory Factor 4 (IRF4)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Interferon Regulatory Factor 4 (IRF4)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Interferon Regulatory Factor 4 (IRF4)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Interferon Regulatory Factor 4 (IRF4)	CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Interferon Regulatory Factor 4 (IRF4)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Interferon Regulatory Factor 4 (IRF4)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Interferon Regulatory Factor 4 (IRF4)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Interferon Regulatory Factor 4 (IRF4)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Interferon Regulatory Factor 4 (IRF4)	CLIA assay for Antigen Detection

Reference

"Cloning of human lymphocyte-specific interferon regulatory factor (hLSIRF/hIRF4) and mapping of the gene to 6p23-p25."
Genomics 37:229-233(1996) [PubMed] [Europe PMC] [Abstract]

"Deregulation of MUM1/IRF4 by chromosomal translocation in multiple myeloma."
Nat. Genet. 17:226-230(1997) [PubMed] [Europe PMC] [Abstract]

"The DNA sequence and analysis of human chromosome 6."
Nature 425:805-811(2003) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"SPI-B activates transcription via a unique proline, serine, and threonine domain and exhibits DNA binding affinity differences from PU.1."
J. Biol. Chem. 274:11115-11124(1999) [PubMed] [Europe PMC] [Abstract]

"Molecular cloning of IBP, a SWAP-70 homologous GEF, which is highly expressed in the immune system."
Hum. Immunol. 64:389-401(2003) [PubMed] [Europe PMC] [Abstract]

"A genome-wide association study identifies novel alleles associated with hair color and skin pigmentation."
PLoS Genet. 4:E1000074-E1000074(2008) [PubMed] [Europe PMC] [Abstract]

"Initial characterization of the human central proteome."
BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

"A polymorphism in IRF4 affects human pigmentation through a tyrosinase-dependent MITF/TFAP2A pathway."
Cell 155:1022-1033(2013) [PubMed] [Europe PMC] [Abstract]

"Solution structure of the IRF domain of human interferon regulator factor 4."
Submitted (OCT-2006) to the PDB data bank