Orosomucoid 2 (ORM2)
AGP-B; AGP2; Alpha-1-Acid Glycoprotein Type 2
Whereas the ORM1 locus was polymorphic, the ORM2 locus appeared to be monomorphic. Later, however, Yuasa et al. (1987) demonstrated polymorphism of the ORM2 locus, with 6 alleles in the Japanese population. By studies of orosomucoid cDNA clones isolated from mouse liver, Escallon et al. (1987) presented evidence for the expression of a second structural locus (ORM2) in human plasma as well as for the detection of genetically determined variation at the ORM2 locus in American blacks by the use of a sensitive enzyme-linked immunoblotting technique. After thin-layer polyacrylamide isoelectric focusing (IEF) in gels containing 6 M urea, the isoprotein species coded by the second locus did not segregate with the predominant alleles at the ORM1 locus. Variation in ORM2 was not observed in U.S. whites or in several other populations studied.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV060Hu01 | Recombinant Orosomucoid 2 (ORM2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV060Hu01 | Monoclonal Antibody to Orosomucoid 2 (ORM2) | WB; IHC; ICC; IP. |
| PAV060Hu01 | Polyclonal Antibody to Orosomucoid 2 (ORM2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV060Hu01 | CLIA Kit for Orosomucoid 2 (ORM2) | CLIA assay for Antigen Detection |
| ELV060Hu01 | ELISA Kit for Orosomucoid 2 (ORM2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV060Mu01 | Recombinant Orosomucoid 2 (ORM2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV060Mu01 | Monoclonal Antibody to Orosomucoid 2 (ORM2) | WB; IHC; ICC; IP. |
| PAV060Mu01 | Polyclonal Antibody to Orosomucoid 2 (ORM2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV060Mu01 | CLIA Kit for Orosomucoid 2 (ORM2) | CLIA assay for Antigen Detection |
| ELV060Mu01 | ELISA Kit for Orosomucoid 2 (ORM2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV060Ra01 | Recombinant Orosomucoid 2 (ORM2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV060Ra01 | Monoclonal Antibody to Orosomucoid 2 (ORM2) | WB; IHC; ICC; IP. |
| PAV060Ra01 | Polyclonal Antibody to Orosomucoid 2 (ORM2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV060Ra01 | CLIA Kit for Orosomucoid 2 (ORM2) | CLIA assay for Antigen Detection |
| ELV060Ra01 | ELISA Kit for Orosomucoid 2 (ORM2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV060Ca01 | Recombinant Orosomucoid 2 (ORM2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV060Ca01 | Monoclonal Antibody to Orosomucoid 2 (ORM2) | WB; IHC; ICC; IP. |
| PAV060Ca01 | Polyclonal Antibody to Orosomucoid 2 (ORM2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV060Ca01 | CLIA Kit for Orosomucoid 2 (ORM2) | CLIA assay for Antigen Detection |
| ELV060Ca01 | ELISA Kit for Orosomucoid 2 (ORM2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV060Po01 | Recombinant Orosomucoid 2 (ORM2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV060Po01 | Monoclonal Antibody to Orosomucoid 2 (ORM2) | WB; IHC; ICC; IP. |
| PAV060Po01 | Polyclonal Antibody to Orosomucoid 2 (ORM2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV060Po01 | CLIA Kit for Orosomucoid 2 (ORM2) | CLIA assay for Antigen Detection |
| ELV060Po01 | ELISA Kit for Orosomucoid 2 (ORM2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV060Bo01 | Recombinant Orosomucoid 2 (ORM2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV060Bo01 | Monoclonal Antibody to Orosomucoid 2 (ORM2) | WB; IHC; ICC; IP. |
| PAV060Bo01 | Polyclonal Antibody to Orosomucoid 2 (ORM2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV060Bo01 | CLIA Kit for Orosomucoid 2 (ORM2) | CLIA assay for Antigen Detection |
| ELV060Bo01 | ELISA Kit for Orosomucoid 2 (ORM2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV060Rb01 | Recombinant Orosomucoid 2 (ORM2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV060Rb01 | Monoclonal Antibody to Orosomucoid 2 (ORM2) | WB; IHC; ICC; IP. |
| PAV060Rb01 | Polyclonal Antibody to Orosomucoid 2 (ORM2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV060Rb01 | CLIA Kit for Orosomucoid 2 (ORM2) | CLIA assay for Antigen Detection |
| ELV060Rb01 | ELISA Kit for Orosomucoid 2 (ORM2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV060Mo01 | Recombinant Orosomucoid 2 (ORM2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV060Mo01 | Monoclonal Antibody to Orosomucoid 2 (ORM2) | WB; IHC; ICC; IP. |
| PAV060Mo01 | Polyclonal Antibody to Orosomucoid 2 (ORM2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV060Mo01 | CLIA Kit for Orosomucoid 2 (ORM2) | CLIA assay for Antigen Detection |
| ELV060Mo01 | ELISA Kit for Orosomucoid 2 (ORM2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"Structure and expression of the genes coding for human alpha 1-acid glycoprotein."
EMBO J. 6:2289-2296(1987) [PubMed] [Europe PMC] [Abstract]
"Structure and characterisation of a duplicated human alpha 1 acid glycoprotein gene."
Gene 66:97-106(1988) [PubMed] [Europe PMC] [Abstract]
"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
"DNA sequence and analysis of human chromosome 9."
Nature 429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"The disulfide bonds of alpha1-acid glycoprotein."
Biochemistry 13:2694-2697(1974) [PubMed] [Europe PMC] [Abstract]
"Analysis of the five glycosylation sites of human alpha 1-acid glycoprotein."
Biochem. J. 283:105-112(1992) [PubMed] [Europe PMC] [Abstract]
"A new strategy for identification of N-glycosylated proteins and unambiguous assignment of their glycosylation sites using HILIC enrichment and partial deglycosylation."
J. Proteome Res. 3:556-566(2004) [PubMed] [Europe PMC] [Abstract]
"A proteomic analysis of human bile."
Mol. Cell. Proteomics 3:715-728(2004) [PubMed] [Europe PMC] [Abstract]
"Screening for N-glycosylated proteins by liquid chromatography mass spectrometry."
Proteomics 4:454-465(2004) [PubMed] [Europe PMC] [Abstract]
"Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry."
J. Proteome Res. 4:2070-2080(2005) [PubMed] [Europe PMC] [Abstract]
"Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."
J. Proteome Res. 8:651-661(2009) [PubMed] [Europe PMC] [Abstract]
"Enrichment of glycopeptides for glycan structure and attachment site identification."
Nat. Methods 6:809-811(2009) [PubMed] [Europe PMC] [Abstract]
"Human urinary glycoproteomics; attachment site specific analysis of N-and O-linked glycosylations by CID and ECD."
Mol. Cell. Proteomics 0:0-0(2011) [PubMed] [Europe PMC] [Abstract]
"Structural insights into differences in drug-binding selectivity between two forms of human {alpha}1-acid glycoprotein genetic variants, the A and F1*S forms."
J. Biol. Chem. 286:14427-14434(2011) [PubMed] [Europe PMC] [Abstract]