Neprilysin (NEP)
CD10; MME; CALLA; SFE; Atriopeptidase; Enkephalinase; Skin fibroblast elastase; Common Acute Lymphoblastic Leukemia Antigen; Membrane Metallo-Endopeptidase
Neprilysin is a zinc-dependent metalloprotease enzyme that degrades a number of small secreted peptides, most notably the amyloid beta peptide whose abnormal misfolding and aggregation in neural tissue has been implicated as a cause of Alzheimer's disease. Synthesized as a membrane-bound protein, the neprilysin ectodomain is released into the extracellular domain after it has been transported from the Golgi apparatus to the cell surface.
In neurons, neprilysin is regulated by the protein nicastrin, a component of the gamma secretase complex that performs a necessary step in processing amyloid precursor protein to amyloid beta.Neprilysin is also associated with other biochemical processes, and is particularly highly expressed in kidney and lung tissues.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV055Hu01 | Recombinant Neprilysin (NEP) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV055Hu01 | Monoclonal Antibody to Neprilysin (NEP) | WB; IHC; ICC; IP. |
| PAV055Hu01 | Polyclonal Antibody to Neprilysin (NEP) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV055Hu01 | CLIA Kit for Neprilysin (NEP) | CLIA assay for Antigen Detection |
| ELV055Hu01 | ELISA Kit for Neprilysin (NEP) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV055Mu01 | Recombinant Neprilysin (NEP) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV055Mu01 | Monoclonal Antibody to Neprilysin (NEP) | WB; IHC; ICC; IP. |
| PAV055Mu01 | Polyclonal Antibody to Neprilysin (NEP) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV055Mu01 | CLIA Kit for Neprilysin (NEP) | CLIA assay for Antigen Detection |
| ELV055Mu01 | ELISA Kit for Neprilysin (NEP) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV055Ra01 | Recombinant Neprilysin (NEP) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV055Ra01 | Monoclonal Antibody to Neprilysin (NEP) | WB; IHC; ICC; IP. |
| PAV055Ra01 | Polyclonal Antibody to Neprilysin (NEP) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV055Ra01 | CLIA Kit for Neprilysin (NEP) | CLIA assay for Antigen Detection |
| ELV055Ra01 | ELISA Kit for Neprilysin (NEP) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV055Ca01 | Recombinant Neprilysin (NEP) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV055Ca01 | Monoclonal Antibody to Neprilysin (NEP) | WB; IHC; ICC; IP. |
| PAV055Ca01 | Polyclonal Antibody to Neprilysin (NEP) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV055Ca01 | CLIA Kit for Neprilysin (NEP) | CLIA assay for Antigen Detection |
| ELV055Ca01 | ELISA Kit for Neprilysin (NEP) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV055Po01 | Recombinant Neprilysin (NEP) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV055Po01 | Monoclonal Antibody to Neprilysin (NEP) | WB; IHC; ICC; IP. |
| PAV055Po01 | Polyclonal Antibody to Neprilysin (NEP) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV055Po01 | CLIA Kit for Neprilysin (NEP) | CLIA assay for Antigen Detection |
| ELV055Po01 | ELISA Kit for Neprilysin (NEP) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV055Bo01 | Recombinant Neprilysin (NEP) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV055Bo01 | Monoclonal Antibody to Neprilysin (NEP) | WB; IHC; ICC; IP. |
| PAV055Bo01 | Polyclonal Antibody to Neprilysin (NEP) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV055Bo01 | CLIA Kit for Neprilysin (NEP) | CLIA assay for Antigen Detection |
| ELV055Bo01 | ELISA Kit for Neprilysin (NEP) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV055Rb01 | Recombinant Neprilysin (NEP) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV055Rb01 | Monoclonal Antibody to Neprilysin (NEP) | WB; IHC; ICC; IP. |
| PAV055Rb01 | Polyclonal Antibody to Neprilysin (NEP) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV055Rb01 | CLIA Kit for Neprilysin (NEP) | CLIA assay for Antigen Detection |
| ELV055Rb01 | ELISA Kit for Neprilysin (NEP) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV055Mo01 | Recombinant Neprilysin (NEP) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV055Mo01 | Monoclonal Antibody to Neprilysin (NEP) | WB; IHC; ICC; IP. |
| PAV055Mo01 | Polyclonal Antibody to Neprilysin (NEP) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV055Mo01 | CLIA Kit for Neprilysin (NEP) | CLIA assay for Antigen Detection |
| ELV055Mo01 | ELISA Kit for Neprilysin (NEP) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
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