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Regenerating Islet Derived Protein 4 (REG4)
Regenerating Islet Derived Protein 4 (REG4)
GISP; REG-IV; RELP; Regenerating Gene Type IV; Gastrointestinal Secretory Protein; REG-like protein
The REG4 gene encodes a deduced 158-amino acid protein with an N-terminal signal peptide of 22 amino acids and a predicted molecular mass of 18.2 kD. REG4 maintains conservation of the 6 cysteine residues present in other known members of the REG family. By Northern blot analysis of intestinal mucosa from 12 individuals with inflammatory bowel disease, Hartupee et al. (2001) identified a 1.1-kb REG4 transcript in all samples. Control specimens had low but detectable expression of REG4. REG4 expression was significantly upregulated by inflammation and tissue injury associated with active Crohn disease and ulcerative colitis. RNA dot-blot analysis showed that most of the tissues expressing REG4 are in the gastrointestinal tract, i.e., colon, small intestine, stomach, and pancreas.
Organism species: Homo sapiens (Human)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Regenerating Islet Derived Protein 4 (REG4) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Regenerating Islet Derived Protein 4 (REG4) Bioactivity
Antibodies
MV022Hu22
Monoclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) Flow Cytometry;ICC/IF
Assay Kits
KEV022Hu
ELISA Kit for Regenerating Islet Derived Protein 4 (REG4) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Regenerating Islet Derived Protein 4 (REG4) CLIA assay for Antigen Detection
Organism species: Mus musculus (Mouse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
V022Mu01
Recombinant Regenerating Islet Derived Protein 4 (REG4) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Regenerating Islet Derived Protein 4 (REG4) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) WB; IHC; ICC; IP.
PV022Mu01
Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) Flow Cytometry;ICC/IF
Assay Kits
KEV022Mu
ELISA Kit for Regenerating Islet Derived Protein 4 (REG4) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Regenerating Islet Derived Protein 4 (REG4) CLIA assay for Antigen Detection
Organism species: Rattus norvegicus (Rat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Regenerating Islet Derived Protein 4 (REG4) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Regenerating Islet Derived Protein 4 (REG4) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) WB; IHC; ICC; IP.
PV022Ra01
Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Regenerating Islet Derived Protein 4 (REG4) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Regenerating Islet Derived Protein 4 (REG4) CLIA assay for Antigen Detection
Organism species: Canis familiaris; Canine (Dog)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Regenerating Islet Derived Protein 4 (REG4) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Regenerating Islet Derived Protein 4 (REG4) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Regenerating Islet Derived Protein 4 (REG4) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Regenerating Islet Derived Protein 4 (REG4) CLIA assay for Antigen Detection
Organism species: Sus scrofa; Porcine (Pig)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Regenerating Islet Derived Protein 4 (REG4) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Regenerating Islet Derived Protein 4 (REG4) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Regenerating Islet Derived Protein 4 (REG4) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Regenerating Islet Derived Protein 4 (REG4) CLIA assay for Antigen Detection
Organism species: Bos taurus; Bovine (Cattle)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Regenerating Islet Derived Protein 4 (REG4) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Regenerating Islet Derived Protein 4 (REG4) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Regenerating Islet Derived Protein 4 (REG4) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Regenerating Islet Derived Protein 4 (REG4) CLIA assay for Antigen Detection
Organism species: Rhesus monkey (Simian)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Regenerating Islet Derived Protein 4 (REG4) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Regenerating Islet Derived Protein 4 (REG4) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Regenerating Islet Derived Protein 4 (REG4) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Regenerating Islet Derived Protein 4 (REG4) CLIA assay for Antigen Detection
Organism species: Chicken (Gallus)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Regenerating Islet Derived Protein 4 (REG4) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Regenerating Islet Derived Protein 4 (REG4) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Regenerating Islet Derived Protein 4 (REG4) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Regenerating Islet Derived Protein 4 (REG4) CLIA assay for Antigen Detection
Organism species: Ovis aries; Ovine (Sheep)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Regenerating Islet Derived Protein 4 (REG4) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Regenerating Islet Derived Protein 4 (REG4) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Regenerating Islet Derived Protein 4 (REG4) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Regenerating Islet Derived Protein 4 (REG4) CLIA assay for Antigen Detection
Organism species: Oryctolagus cuniculus (Rabbit)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Regenerating Islet Derived Protein 4 (REG4) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Regenerating Islet Derived Protein 4 (REG4) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Regenerating Islet Derived Protein 4 (REG4) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Regenerating Islet Derived Protein 4 (REG4) CLIA assay for Antigen Detection
Organism species: Cavia (Guinea pig )
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Regenerating Islet Derived Protein 4 (REG4) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Regenerating Islet Derived Protein 4 (REG4) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Regenerating Islet Derived Protein 4 (REG4) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Regenerating Islet Derived Protein 4 (REG4) CLIA assay for Antigen Detection
Organism species: Equus caballus; Equine (Horse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Regenerating Islet Derived Protein 4 (REG4) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Regenerating Islet Derived Protein 4 (REG4) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Regenerating Islet Derived Protein 4 (REG4) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Regenerating Islet Derived Protein 4 (REG4) CLIA assay for Antigen Detection
Organism species: Capra hircus; Caprine (Goat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Regenerating Islet Derived Protein 4 (REG4) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Regenerating Islet Derived Protein 4 (REG4) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Regenerating Islet Derived Protein 4 (REG4) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Regenerating Islet Derived Protein 4 (REG4) CLIA assay for Antigen Detection
Organism species: Pan-species (General)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Regenerating Islet Derived Protein 4 (REG4) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Regenerating Islet Derived Protein 4 (REG4) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Regenerating Islet Derived Protein 4 (REG4) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Regenerating Islet Derived Protein 4 (REG4) CLIA assay for Antigen Detection
Reference
"Isolation and characterization of a cDNA encoding a novel member of the human regenerating protein family: Reg IV." Biochim. Biophys. Acta 1518:287-293(2001) [PubMed ] [Europe PMC ] [Abstract ]
"RELP, a novel human REG-like protein with up-regulated expression in inflammatory and metaplastic gastrointestinal mucosa." Am. J. Pathol. 163:11-20(2003) [PubMed ] [Europe PMC ] [Abstract ]
"Reg IV, a new member of the regenerating gene family, is overexpressed in colorectal carcinomas." Int. J. Cancer 103:185-193(2003) [PubMed ] [Europe PMC ] [Abstract ]
"The DNA sequence and biological annotation of human chromosome 1." Nature 441:315-321(2006) [PubMed ] [Europe PMC ] [Abstract ]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." Genome Res. 14:2121-2127(2004) [PubMed ] [Europe PMC ] [Abstract ]
"Signal peptide prediction based on analysis of experimentally verified cleavage sites." Protein Sci. 13:2819-2824(2004) [PubMed ] [Europe PMC ] [Abstract ]
"Human RegIV protein adopts a typical C-type lectin fold but binds mannan with two calcium-independent sites." J. Mol. Biol. 402:682-695(2010) [PubMed ] [Europe PMC ] [Abstract ]
