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Cadherin, Heart (CDHH)

CDH13; P105; T-cad; Cadherin 13; T-Cadherin; H-Cadherin; Truncated cadherin

T-cadherin also known as cadherin 13, H-cadherin (heart) (CDH13) is a unique member of cadherin superfamily because it lacks the transmembrane and cytoplasmic domains and is anchored to the cells membrane through the GPI anchor. Classical cadherins are necessary for cell-cell contacts, dynamic regulation of morphogenetic processes in embryos and tissue integrity in adult organism. Cadherins function as membrane receptors mediating outside-in signals, activating small GTPases and beta-catenin/Wnt pathway, and resulting in dynamic cytoskeleton reorganization and changes in the phenotype. T-cadherin is a GPI-anchored member of cadherin superfamily, which lacks a direct contact with cytoskeleton and therefore is not involved in cell-cell adhesion.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins U939Hu01 Recombinant Cadherin, Heart (CDHH) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Cadherin, Heart (CDHH) Bioactivity
Antibodies MU939Hu22 Monoclonal Antibody to Cadherin, Heart (CDHH) WB; IHC; ICC; IP.
PU939Hu01 Polyclonal Antibody to Cadherin, Heart (CDHH) WB; IHC; ICC; IF.
LU939Hu71 Biotin Linked-Polyclonal Antibody to Cadherin, Heart (CDHH) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Cadherin, Heart (CDHH) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Cadherin, Heart (CDHH) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Cadherin, Heart (CDHH) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Cadherin, Heart (CDHH) Flow Cytometry;ICC/IF
Assay Kits KEU939Hu ELISA Kit for Cadherin, Heart (CDHH) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Cadherin, Heart (CDHH) CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins U939Mu02 Recombinant Cadherin, Heart (CDHH) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Cadherin, Heart (CDHH) Bioactivity
Antibodies NONE Monoclonal Antibody to Cadherin, Heart (CDHH) WB; IHC; ICC; IP.
PU939Mu01 Polyclonal Antibody to Cadherin, Heart (CDHH) WB; IHC; ICC; IF.
LU939Mu71 Biotin Linked-Polyclonal Antibody to Cadherin, Heart (CDHH) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Cadherin, Heart (CDHH) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Cadherin, Heart (CDHH) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Cadherin, Heart (CDHH) Flow Cytometry
LU939Mu81 FITC Linked-Polyclonal Antibody to Cadherin, Heart (CDHH) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Cadherin, Heart (CDHH) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Cadherin, Heart (CDHH) CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Cadherin, Heart (CDHH) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Cadherin, Heart (CDHH) Bioactivity
Antibodies NONE Monoclonal Antibody to Cadherin, Heart (CDHH) WB; IHC; ICC; IP.
PU939Ra01 Polyclonal Antibody to Cadherin, Heart (CDHH) WB; IHC; ICC; IF.
LU939Ra71 Biotin Linked-Polyclonal Antibody to Cadherin, Heart (CDHH) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Cadherin, Heart (CDHH) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Cadherin, Heart (CDHH) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Cadherin, Heart (CDHH) Flow Cytometry
LU939Ra81 FITC Linked-Polyclonal Antibody to Cadherin, Heart (CDHH) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Cadherin, Heart (CDHH) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Cadherin, Heart (CDHH) CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Cadherin, Heart (CDHH) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Cadherin, Heart (CDHH) Bioactivity
Antibodies NONE Monoclonal Antibody to Cadherin, Heart (CDHH) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Cadherin, Heart (CDHH) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Cadherin, Heart (CDHH) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Cadherin, Heart (CDHH) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Cadherin, Heart (CDHH) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Cadherin, Heart (CDHH) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Cadherin, Heart (CDHH) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Cadherin, Heart (CDHH) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Cadherin, Heart (CDHH) CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Cadherin, Heart (CDHH) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Cadherin, Heart (CDHH) Bioactivity
Antibodies NONE Monoclonal Antibody to Cadherin, Heart (CDHH) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Cadherin, Heart (CDHH) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Cadherin, Heart (CDHH) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Cadherin, Heart (CDHH) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Cadherin, Heart (CDHH) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Cadherin, Heart (CDHH) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Cadherin, Heart (CDHH) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Cadherin, Heart (CDHH) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Cadherin, Heart (CDHH) CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Cadherin, Heart (CDHH) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Cadherin, Heart (CDHH) Bioactivity
Antibodies NONE Monoclonal Antibody to Cadherin, Heart (CDHH) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Cadherin, Heart (CDHH) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Cadherin, Heart (CDHH) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Cadherin, Heart (CDHH) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Cadherin, Heart (CDHH) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Cadherin, Heart (CDHH) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Cadherin, Heart (CDHH) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Cadherin, Heart (CDHH) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Cadherin, Heart (CDHH) CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Cadherin, Heart (CDHH) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Cadherin, Heart (CDHH) Bioactivity
Antibodies NONE Monoclonal Antibody to Cadherin, Heart (CDHH) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Cadherin, Heart (CDHH) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Cadherin, Heart (CDHH) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Cadherin, Heart (CDHH) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Cadherin, Heart (CDHH) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Cadherin, Heart (CDHH) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Cadherin, Heart (CDHH) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Cadherin, Heart (CDHH) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Cadherin, Heart (CDHH) CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Cadherin, Heart (CDHH) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Cadherin, Heart (CDHH) Bioactivity
Antibodies NONE Monoclonal Antibody to Cadherin, Heart (CDHH) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Cadherin, Heart (CDHH) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Cadherin, Heart (CDHH) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Cadherin, Heart (CDHH) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Cadherin, Heart (CDHH) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Cadherin, Heart (CDHH) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Cadherin, Heart (CDHH) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Cadherin, Heart (CDHH) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Cadherin, Heart (CDHH) CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Cadherin, Heart (CDHH) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Cadherin, Heart (CDHH) Bioactivity
Antibodies NONE Monoclonal Antibody to Cadherin, Heart (CDHH) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Cadherin, Heart (CDHH) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Cadherin, Heart (CDHH) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Cadherin, Heart (CDHH) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Cadherin, Heart (CDHH) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Cadherin, Heart (CDHH) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Cadherin, Heart (CDHH) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Cadherin, Heart (CDHH) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Cadherin, Heart (CDHH) CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Cadherin, Heart (CDHH) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Cadherin, Heart (CDHH) Bioactivity
Antibodies NONE Monoclonal Antibody to Cadherin, Heart (CDHH) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Cadherin, Heart (CDHH) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Cadherin, Heart (CDHH) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Cadherin, Heart (CDHH) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Cadherin, Heart (CDHH) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Cadherin, Heart (CDHH) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Cadherin, Heart (CDHH) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Cadherin, Heart (CDHH) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Cadherin, Heart (CDHH) CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Cadherin, Heart (CDHH) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Cadherin, Heart (CDHH) Bioactivity
Antibodies NONE Monoclonal Antibody to Cadherin, Heart (CDHH) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Cadherin, Heart (CDHH) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Cadherin, Heart (CDHH) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Cadherin, Heart (CDHH) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Cadherin, Heart (CDHH) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Cadherin, Heart (CDHH) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Cadherin, Heart (CDHH) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Cadherin, Heart (CDHH) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Cadherin, Heart (CDHH) CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Cadherin, Heart (CDHH) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Cadherin, Heart (CDHH) Bioactivity
Antibodies NONE Monoclonal Antibody to Cadherin, Heart (CDHH) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Cadherin, Heart (CDHH) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Cadherin, Heart (CDHH) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Cadherin, Heart (CDHH) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Cadherin, Heart (CDHH) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Cadherin, Heart (CDHH) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Cadherin, Heart (CDHH) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Cadherin, Heart (CDHH) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Cadherin, Heart (CDHH) CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Cadherin, Heart (CDHH) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Cadherin, Heart (CDHH) Bioactivity
Antibodies NONE Monoclonal Antibody to Cadherin, Heart (CDHH) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Cadherin, Heart (CDHH) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Cadherin, Heart (CDHH) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Cadherin, Heart (CDHH) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Cadherin, Heart (CDHH) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Cadherin, Heart (CDHH) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Cadherin, Heart (CDHH) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Cadherin, Heart (CDHH) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Cadherin, Heart (CDHH) CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Cadherin, Heart (CDHH) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Cadherin, Heart (CDHH) Bioactivity
Antibodies NONE Monoclonal Antibody to Cadherin, Heart (CDHH) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Cadherin, Heart (CDHH) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Cadherin, Heart (CDHH) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Cadherin, Heart (CDHH) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Cadherin, Heart (CDHH) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Cadherin, Heart (CDHH) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Cadherin, Heart (CDHH) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Cadherin, Heart (CDHH) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Cadherin, Heart (CDHH) CLIA assay for Antigen Detection

Reference

"Cloning of five human cadherins clarifies characteristic features of cadherin extracellular domain and provides further evidence for two structurally different types of cadherin."
Cell Adhes. Commun. 2:15-26(1994) [PubMed] [Europe PMC] [Abstract]

"H-cadherin, a novel cadherin with growth inhibitory functions and diminished expression in human breast cancer."
Nat. Med. 2:776-782(1996) [PubMed] [Europe PMC] [Abstract]

"The H-cadherin (CDH13) gene is inactivated in human lung cancer."
Hum. Genet. 103:96-101(1998) [PubMed] [Europe PMC] [Abstract]

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

"The sequence and analysis of duplication-rich human chromosome 16."
Nature 432:988-994(2004) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Identification of an atypical lipoprotein-binding protein from human aortic smooth muscle as T-cadherin."
FEBS Lett. 421:208-212(1998) [PubMed] [Europe PMC] [Abstract]

"Expression of T-cadherin (CDH13, H-Cadherin) in human brain and its characteristics as a negative growth regulator of epidermal growth factor in neuroblastoma cells."
J. Neurochem. 74:1489-1497(2000) [PubMed] [Europe PMC] [Abstract]

"The glycosyl phosphatidylinositol anchor of human T-cadherin binds lipoproteins."
Biochem. Biophys. Res. Commun. 276:1240-1247(2000) [PubMed] [Europe PMC] [Abstract]

"Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry."
J. Proteome Res. 4:2070-2080(2005) [PubMed] [Europe PMC] [Abstract]

"Modification-specific proteomics of plasma membrane proteins: identification and characterization of glycosylphosphatidylinositol-anchored proteins released upon phospholipase D treatment."
J. Proteome Res. 5:935-943(2006) [PubMed] [Europe PMC] [Abstract]

"Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."
J. Proteome Res. 8:651-661(2009) [PubMed] [Europe PMC] [Abstract]

"Resequencing of 29 candidate genes in patients with familial and sporadic amyotrophic lateral sclerosis."
Arch. Neurol. 68:587-593(2011) [PubMed] [Europe PMC] [Abstract]