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S Antigen (SAG)

S-AG; Retina And Pineal Gland; Arrestin; 48 kDa protein; Retinal S-antigen; Rod photoreceptor arrestin

S-antigen; retina and pineal gland  is a Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. S-arrestin, is a major soluble photoreceptor protein that is involved in desensitization of the photoactivated transduction cascade. It is expressed in the retina and the pineal gland and inhibits coupling of rhodopsin to transducin in vitro. Additionally, S-arrestin is highly antigenic, and is capable of inducing experimental autoimmune uveoretinitis. Mutations in this gene have been associated with Oguchi disease, a rare autosomal recessive form of night blindness.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins U930Hu01 Recombinant S Antigen (SAG) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native S Antigen (SAG) Bioactivity
Antibodies NONE Monoclonal Antibody to S Antigen (SAG) WB; IHC; ICC; IP.
PU930Hu01 Polyclonal Antibody to S Antigen (SAG) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to S Antigen (SAG) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to S Antigen (SAG) IHC, WB
NONE HRP Linked-Polyclonal Antibody to S Antigen (SAG) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to S Antigen (SAG) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to S Antigen (SAG) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for S Antigen (SAG) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for S Antigen (SAG) CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins U930Mu01 Recombinant S Antigen (SAG) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native S Antigen (SAG) Bioactivity
Antibodies NONE Monoclonal Antibody to S Antigen (SAG) WB; IHC; ICC; IP.
PU930Mu01 Polyclonal Antibody to S Antigen (SAG) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to S Antigen (SAG) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to S Antigen (SAG) IHC, WB
NONE HRP Linked-Polyclonal Antibody to S Antigen (SAG) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to S Antigen (SAG) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to S Antigen (SAG) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for S Antigen (SAG) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for S Antigen (SAG) CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant S Antigen (SAG) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native S Antigen (SAG) Bioactivity
Antibodies NONE Monoclonal Antibody to S Antigen (SAG) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to S Antigen (SAG) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to S Antigen (SAG) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to S Antigen (SAG) IHC, WB
NONE HRP Linked-Polyclonal Antibody to S Antigen (SAG) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to S Antigen (SAG) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to S Antigen (SAG) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for S Antigen (SAG) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for S Antigen (SAG) CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant S Antigen (SAG) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native S Antigen (SAG) Bioactivity
Antibodies NONE Monoclonal Antibody to S Antigen (SAG) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to S Antigen (SAG) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to S Antigen (SAG) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to S Antigen (SAG) IHC, WB
NONE HRP Linked-Polyclonal Antibody to S Antigen (SAG) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to S Antigen (SAG) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to S Antigen (SAG) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for S Antigen (SAG) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for S Antigen (SAG) CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant S Antigen (SAG) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native S Antigen (SAG) Bioactivity
Antibodies NONE Monoclonal Antibody to S Antigen (SAG) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to S Antigen (SAG) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to S Antigen (SAG) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to S Antigen (SAG) IHC, WB
NONE HRP Linked-Polyclonal Antibody to S Antigen (SAG) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to S Antigen (SAG) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to S Antigen (SAG) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for S Antigen (SAG) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for S Antigen (SAG) CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant S Antigen (SAG) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native S Antigen (SAG) Bioactivity
Antibodies NONE Monoclonal Antibody to S Antigen (SAG) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to S Antigen (SAG) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to S Antigen (SAG) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to S Antigen (SAG) IHC, WB
NONE HRP Linked-Polyclonal Antibody to S Antigen (SAG) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to S Antigen (SAG) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to S Antigen (SAG) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for S Antigen (SAG) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for S Antigen (SAG) CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant S Antigen (SAG) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native S Antigen (SAG) Bioactivity
Antibodies NONE Monoclonal Antibody to S Antigen (SAG) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to S Antigen (SAG) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to S Antigen (SAG) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to S Antigen (SAG) IHC, WB
NONE HRP Linked-Polyclonal Antibody to S Antigen (SAG) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to S Antigen (SAG) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to S Antigen (SAG) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for S Antigen (SAG) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for S Antigen (SAG) CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant S Antigen (SAG) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native S Antigen (SAG) Bioactivity
Antibodies NONE Monoclonal Antibody to S Antigen (SAG) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to S Antigen (SAG) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to S Antigen (SAG) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to S Antigen (SAG) IHC, WB
NONE HRP Linked-Polyclonal Antibody to S Antigen (SAG) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to S Antigen (SAG) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to S Antigen (SAG) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for S Antigen (SAG) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for S Antigen (SAG) CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant S Antigen (SAG) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native S Antigen (SAG) Bioactivity
Antibodies NONE Monoclonal Antibody to S Antigen (SAG) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to S Antigen (SAG) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to S Antigen (SAG) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to S Antigen (SAG) IHC, WB
NONE HRP Linked-Polyclonal Antibody to S Antigen (SAG) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to S Antigen (SAG) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to S Antigen (SAG) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for S Antigen (SAG) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for S Antigen (SAG) CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant S Antigen (SAG) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native S Antigen (SAG) Bioactivity
Antibodies NONE Monoclonal Antibody to S Antigen (SAG) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to S Antigen (SAG) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to S Antigen (SAG) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to S Antigen (SAG) IHC, WB
NONE HRP Linked-Polyclonal Antibody to S Antigen (SAG) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to S Antigen (SAG) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to S Antigen (SAG) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for S Antigen (SAG) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for S Antigen (SAG) CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant S Antigen (SAG) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native S Antigen (SAG) Bioactivity
Antibodies NONE Monoclonal Antibody to S Antigen (SAG) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to S Antigen (SAG) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to S Antigen (SAG) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to S Antigen (SAG) IHC, WB
NONE HRP Linked-Polyclonal Antibody to S Antigen (SAG) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to S Antigen (SAG) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to S Antigen (SAG) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for S Antigen (SAG) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for S Antigen (SAG) CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant S Antigen (SAG) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native S Antigen (SAG) Bioactivity
Antibodies NONE Monoclonal Antibody to S Antigen (SAG) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to S Antigen (SAG) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to S Antigen (SAG) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to S Antigen (SAG) IHC, WB
NONE HRP Linked-Polyclonal Antibody to S Antigen (SAG) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to S Antigen (SAG) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to S Antigen (SAG) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for S Antigen (SAG) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for S Antigen (SAG) CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant S Antigen (SAG) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native S Antigen (SAG) Bioactivity
Antibodies NONE Monoclonal Antibody to S Antigen (SAG) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to S Antigen (SAG) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to S Antigen (SAG) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to S Antigen (SAG) IHC, WB
NONE HRP Linked-Polyclonal Antibody to S Antigen (SAG) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to S Antigen (SAG) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to S Antigen (SAG) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for S Antigen (SAG) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for S Antigen (SAG) CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant S Antigen (SAG) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native S Antigen (SAG) Bioactivity
Antibodies NONE Monoclonal Antibody to S Antigen (SAG) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to S Antigen (SAG) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to S Antigen (SAG) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to S Antigen (SAG) IHC, WB
NONE HRP Linked-Polyclonal Antibody to S Antigen (SAG) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to S Antigen (SAG) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to S Antigen (SAG) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for S Antigen (SAG) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for S Antigen (SAG) CLIA assay for Antigen Detection

Reference

"The sequence of human retinal S-antigen reveals similarities with alpha-transducin."
FEBS Lett. 234:39-43(1988) [PubMed] [Europe PMC] [Abstract]

Erratum
FEBS Lett. 236:507-507(1988)

"Defects in the rhodopsin kinase gene in the Oguchi form of stationary night blindness."
Nat. Genet. 15:175-178(1997) [PubMed] [Europe PMC] [Abstract]

"Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]

"Mapping of transcription start sites of human retina expressed genes."
BMC Genomics 8:42-42(2007) [PubMed] [Europe PMC] [Abstract]

"A homozygous 1-base pair deletion in the arrestin gene is a frequent cause of Oguchi disease in Japanese."
Nat. Genet. 10:360-362(1995) [PubMed] [Europe PMC] [Abstract]

"Arrestin gene mutations in autosomal recessive retinitis pigmentosa."
Arch. Ophthalmol. 116:498-501(1998) [PubMed] [Europe PMC] [Abstract]

"Robust self-association is a common feature of mammalian visual arrestin-1."
Biochemistry 50:2235-2242(2011) [PubMed] [Europe PMC] [Abstract]

"Evaluation of the human arrestin gene in patients with retinitis pigmentosa and stationary night blindness."
Invest. Ophthalmol. Vis. Sci. 39:665-670(1998) [PubMed] [Europe PMC] [Abstract]