Mothers Against Decapentaplegic Homolog 4 (Smad4)
DPC4; JIP; MADH4; Deletion target in pancreatic carcinoma 4
SMAD4 is a 552 amino acid protein involved in cell signaling. It belongs to the Darfwin family of proteins which modulate members of the TGF beta protein superfamily. It binds receptor regulated SMADs such as SMAD1 or SMAD2 and forms a complex that binds to DNA and serves as a transcription factor. It is the only known mammalian coSMAD. It is a homolog of the Drosophila protein: "Mothers against decapentaplegic".
The SMAD proteins are homologs of both the drosophila protein, mothers against decapentaplegic (MAD) and the C. elegans protein SMA. The name is a combination of the two. During Drosophila research, it was found that a mutation in the gene, MAD, in the mother, repressed the gene, decapentaplegic, in the embryo.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU916Hu01 | Recombinant Mothers Against Decapentaplegic Homolog 4 (Smad4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU916Hu01 | Monoclonal Antibody to Mothers Against Decapentaplegic Homolog 4 (Smad4) | WB; IHC; ICC; IP. |
| PAU916Hu01 | Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 4 (Smad4) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU916Hu01 | CLIA Kit for Mothers Against Decapentaplegic Homolog 4 (Smad4) | CLIA assay for Antigen Detection |
| ELU916Hu01 | ELISA Kit for Mothers Against Decapentaplegic Homolog 4 (Smad4) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU916Mu01 | Recombinant Mothers Against Decapentaplegic Homolog 4 (Smad4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU916Mu01 | Monoclonal Antibody to Mothers Against Decapentaplegic Homolog 4 (Smad4) | WB; IHC; ICC; IP. |
| PAU916Mu01 | Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 4 (Smad4) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU916Mu01 | CLIA Kit for Mothers Against Decapentaplegic Homolog 4 (Smad4) | CLIA assay for Antigen Detection |
| ELU916Mu01 | ELISA Kit for Mothers Against Decapentaplegic Homolog 4 (Smad4) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU916Ra01 | Recombinant Mothers Against Decapentaplegic Homolog 4 (Smad4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU916Ra01 | Monoclonal Antibody to Mothers Against Decapentaplegic Homolog 4 (Smad4) | WB; IHC; ICC; IP. |
| PAU916Ra01 | Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 4 (Smad4) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU916Ra01 | CLIA Kit for Mothers Against Decapentaplegic Homolog 4 (Smad4) | CLIA assay for Antigen Detection |
| ELU916Ra01 | ELISA Kit for Mothers Against Decapentaplegic Homolog 4 (Smad4) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU916Ca01 | Recombinant Mothers Against Decapentaplegic Homolog 4 (Smad4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU916Ca01 | Monoclonal Antibody to Mothers Against Decapentaplegic Homolog 4 (Smad4) | WB; IHC; ICC; IP. |
| PAU916Ca01 | Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 4 (Smad4) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU916Ca01 | CLIA Kit for Mothers Against Decapentaplegic Homolog 4 (Smad4) | CLIA assay for Antigen Detection |
| ELU916Ca01 | ELISA Kit for Mothers Against Decapentaplegic Homolog 4 (Smad4) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU916Po01 | Recombinant Mothers Against Decapentaplegic Homolog 4 (Smad4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU916Po01 | Monoclonal Antibody to Mothers Against Decapentaplegic Homolog 4 (Smad4) | WB; IHC; ICC; IP. |
| PAU916Po01 | Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 4 (Smad4) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU916Po01 | CLIA Kit for Mothers Against Decapentaplegic Homolog 4 (Smad4) | CLIA assay for Antigen Detection |
| ELU916Po01 | ELISA Kit for Mothers Against Decapentaplegic Homolog 4 (Smad4) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU916Bo01 | Recombinant Mothers Against Decapentaplegic Homolog 4 (Smad4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU916Bo01 | Monoclonal Antibody to Mothers Against Decapentaplegic Homolog 4 (Smad4) | WB; IHC; ICC; IP. |
| PAU916Bo01 | Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 4 (Smad4) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU916Bo01 | CLIA Kit for Mothers Against Decapentaplegic Homolog 4 (Smad4) | CLIA assay for Antigen Detection |
| ELU916Bo01 | ELISA Kit for Mothers Against Decapentaplegic Homolog 4 (Smad4) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU916Rb01 | Recombinant Mothers Against Decapentaplegic Homolog 4 (Smad4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU916Rb01 | Monoclonal Antibody to Mothers Against Decapentaplegic Homolog 4 (Smad4) | WB; IHC; ICC; IP. |
| PAU916Rb01 | Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 4 (Smad4) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU916Rb01 | CLIA Kit for Mothers Against Decapentaplegic Homolog 4 (Smad4) | CLIA assay for Antigen Detection |
| ELU916Rb01 | ELISA Kit for Mothers Against Decapentaplegic Homolog 4 (Smad4) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU916Mo01 | Recombinant Mothers Against Decapentaplegic Homolog 4 (Smad4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU916Mo01 | Monoclonal Antibody to Mothers Against Decapentaplegic Homolog 4 (Smad4) | WB; IHC; ICC; IP. |
| PAU916Mo01 | Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 4 (Smad4) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU916Mo01 | CLIA Kit for Mothers Against Decapentaplegic Homolog 4 (Smad4) | CLIA assay for Antigen Detection |
| ELU916Mo01 | ELISA Kit for Mothers Against Decapentaplegic Homolog 4 (Smad4) | Enzyme-linked immunosorbent assay for Antigen Detection |
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