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Histone Acetyltransferase 1 (HAT1)

KAT1; Histone acetyltransferase type B catalytic subunit

Histone acetyltransferases (HAT) are enzymes that acetylate conserved lysine amino acids on histone proteins by transferring an acetyl group from acetyl CoA to form ε-N-acetyl lysine.

Histone acetyltransferase 1, alsoknown as HAT1, is a type B histone acetyltransferase (HAT) that is involved in the rapid acetylation of newly synthesized cytoplasmic histones, which are in turn imported into the nucleus for de novo deposition onto nascent DNA chains. Histone acetylation, particularly of histone H4, plays an important role in replication-dependent chromatin assembly. Specifically, this HAT can acetylate soluble but not nucleosomal histone H4 at lysines 5 and 12, and to a lesser degree, histone H2A at lysine 5.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins U890Hu01 Recombinant Histone Acetyltransferase 1 (HAT1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Histone Acetyltransferase 1 (HAT1) Bioactivity
Antibodies MU890Hu22 Monoclonal Antibody to Histone Acetyltransferase 1 (HAT1) WB; IHC; ICC; IP.
PU890Hu01 Polyclonal Antibody to Histone Acetyltransferase 1 (HAT1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Histone Acetyltransferase 1 (HAT1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Histone Acetyltransferase 1 (HAT1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Histone Acetyltransferase 1 (HAT1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Histone Acetyltransferase 1 (HAT1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Histone Acetyltransferase 1 (HAT1) Flow Cytometry;ICC/IF
Assay Kits KEU890Hu ELISA Kit for Histone Acetyltransferase 1 (HAT1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Histone Acetyltransferase 1 (HAT1) CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins U890Mu01 Recombinant Histone Acetyltransferase 1 (HAT1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Histone Acetyltransferase 1 (HAT1) Bioactivity
Antibodies NONE Monoclonal Antibody to Histone Acetyltransferase 1 (HAT1) WB; IHC; ICC; IP.
PU890Mu01 Polyclonal Antibody to Histone Acetyltransferase 1 (HAT1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Histone Acetyltransferase 1 (HAT1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Histone Acetyltransferase 1 (HAT1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Histone Acetyltransferase 1 (HAT1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Histone Acetyltransferase 1 (HAT1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Histone Acetyltransferase 1 (HAT1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Histone Acetyltransferase 1 (HAT1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Histone Acetyltransferase 1 (HAT1) CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins U890Ra01 Recombinant Histone Acetyltransferase 1 (HAT1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Histone Acetyltransferase 1 (HAT1) Bioactivity
Antibodies MU890Ra21 Monoclonal Antibody to Histone Acetyltransferase 1 (HAT1) WB; IHC; ICC; IP.
PU890Ra01 Polyclonal Antibody to Histone Acetyltransferase 1 (HAT1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Histone Acetyltransferase 1 (HAT1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Histone Acetyltransferase 1 (HAT1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Histone Acetyltransferase 1 (HAT1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Histone Acetyltransferase 1 (HAT1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Histone Acetyltransferase 1 (HAT1) Flow Cytometry;ICC/IF
Assay Kits KEU890Ra ELISA Kit for Histone Acetyltransferase 1 (HAT1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Histone Acetyltransferase 1 (HAT1) CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Histone Acetyltransferase 1 (HAT1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Histone Acetyltransferase 1 (HAT1) Bioactivity
Antibodies NONE Monoclonal Antibody to Histone Acetyltransferase 1 (HAT1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Histone Acetyltransferase 1 (HAT1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Histone Acetyltransferase 1 (HAT1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Histone Acetyltransferase 1 (HAT1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Histone Acetyltransferase 1 (HAT1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Histone Acetyltransferase 1 (HAT1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Histone Acetyltransferase 1 (HAT1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Histone Acetyltransferase 1 (HAT1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Histone Acetyltransferase 1 (HAT1) CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Histone Acetyltransferase 1 (HAT1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Histone Acetyltransferase 1 (HAT1) Bioactivity
Antibodies NONE Monoclonal Antibody to Histone Acetyltransferase 1 (HAT1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Histone Acetyltransferase 1 (HAT1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Histone Acetyltransferase 1 (HAT1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Histone Acetyltransferase 1 (HAT1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Histone Acetyltransferase 1 (HAT1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Histone Acetyltransferase 1 (HAT1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Histone Acetyltransferase 1 (HAT1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Histone Acetyltransferase 1 (HAT1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Histone Acetyltransferase 1 (HAT1) CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Histone Acetyltransferase 1 (HAT1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Histone Acetyltransferase 1 (HAT1) Bioactivity
Antibodies NONE Monoclonal Antibody to Histone Acetyltransferase 1 (HAT1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Histone Acetyltransferase 1 (HAT1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Histone Acetyltransferase 1 (HAT1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Histone Acetyltransferase 1 (HAT1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Histone Acetyltransferase 1 (HAT1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Histone Acetyltransferase 1 (HAT1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Histone Acetyltransferase 1 (HAT1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Histone Acetyltransferase 1 (HAT1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Histone Acetyltransferase 1 (HAT1) CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Histone Acetyltransferase 1 (HAT1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Histone Acetyltransferase 1 (HAT1) Bioactivity
Antibodies NONE Monoclonal Antibody to Histone Acetyltransferase 1 (HAT1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Histone Acetyltransferase 1 (HAT1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Histone Acetyltransferase 1 (HAT1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Histone Acetyltransferase 1 (HAT1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Histone Acetyltransferase 1 (HAT1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Histone Acetyltransferase 1 (HAT1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Histone Acetyltransferase 1 (HAT1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Histone Acetyltransferase 1 (HAT1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Histone Acetyltransferase 1 (HAT1) CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Histone Acetyltransferase 1 (HAT1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Histone Acetyltransferase 1 (HAT1) Bioactivity
Antibodies NONE Monoclonal Antibody to Histone Acetyltransferase 1 (HAT1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Histone Acetyltransferase 1 (HAT1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Histone Acetyltransferase 1 (HAT1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Histone Acetyltransferase 1 (HAT1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Histone Acetyltransferase 1 (HAT1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Histone Acetyltransferase 1 (HAT1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Histone Acetyltransferase 1 (HAT1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Histone Acetyltransferase 1 (HAT1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Histone Acetyltransferase 1 (HAT1) CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Histone Acetyltransferase 1 (HAT1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Histone Acetyltransferase 1 (HAT1) Bioactivity
Antibodies NONE Monoclonal Antibody to Histone Acetyltransferase 1 (HAT1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Histone Acetyltransferase 1 (HAT1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Histone Acetyltransferase 1 (HAT1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Histone Acetyltransferase 1 (HAT1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Histone Acetyltransferase 1 (HAT1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Histone Acetyltransferase 1 (HAT1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Histone Acetyltransferase 1 (HAT1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Histone Acetyltransferase 1 (HAT1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Histone Acetyltransferase 1 (HAT1) CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Histone Acetyltransferase 1 (HAT1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Histone Acetyltransferase 1 (HAT1) Bioactivity
Antibodies NONE Monoclonal Antibody to Histone Acetyltransferase 1 (HAT1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Histone Acetyltransferase 1 (HAT1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Histone Acetyltransferase 1 (HAT1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Histone Acetyltransferase 1 (HAT1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Histone Acetyltransferase 1 (HAT1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Histone Acetyltransferase 1 (HAT1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Histone Acetyltransferase 1 (HAT1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Histone Acetyltransferase 1 (HAT1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Histone Acetyltransferase 1 (HAT1) CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Histone Acetyltransferase 1 (HAT1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Histone Acetyltransferase 1 (HAT1) Bioactivity
Antibodies NONE Monoclonal Antibody to Histone Acetyltransferase 1 (HAT1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Histone Acetyltransferase 1 (HAT1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Histone Acetyltransferase 1 (HAT1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Histone Acetyltransferase 1 (HAT1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Histone Acetyltransferase 1 (HAT1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Histone Acetyltransferase 1 (HAT1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Histone Acetyltransferase 1 (HAT1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Histone Acetyltransferase 1 (HAT1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Histone Acetyltransferase 1 (HAT1) CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Histone Acetyltransferase 1 (HAT1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Histone Acetyltransferase 1 (HAT1) Bioactivity
Antibodies NONE Monoclonal Antibody to Histone Acetyltransferase 1 (HAT1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Histone Acetyltransferase 1 (HAT1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Histone Acetyltransferase 1 (HAT1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Histone Acetyltransferase 1 (HAT1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Histone Acetyltransferase 1 (HAT1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Histone Acetyltransferase 1 (HAT1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Histone Acetyltransferase 1 (HAT1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Histone Acetyltransferase 1 (HAT1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Histone Acetyltransferase 1 (HAT1) CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Histone Acetyltransferase 1 (HAT1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Histone Acetyltransferase 1 (HAT1) Bioactivity
Antibodies NONE Monoclonal Antibody to Histone Acetyltransferase 1 (HAT1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Histone Acetyltransferase 1 (HAT1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Histone Acetyltransferase 1 (HAT1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Histone Acetyltransferase 1 (HAT1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Histone Acetyltransferase 1 (HAT1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Histone Acetyltransferase 1 (HAT1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Histone Acetyltransferase 1 (HAT1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Histone Acetyltransferase 1 (HAT1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Histone Acetyltransferase 1 (HAT1) CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Histone Acetyltransferase 1 (HAT1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Histone Acetyltransferase 1 (HAT1) Bioactivity
Antibodies NONE Monoclonal Antibody to Histone Acetyltransferase 1 (HAT1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Histone Acetyltransferase 1 (HAT1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Histone Acetyltransferase 1 (HAT1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Histone Acetyltransferase 1 (HAT1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Histone Acetyltransferase 1 (HAT1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Histone Acetyltransferase 1 (HAT1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Histone Acetyltransferase 1 (HAT1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Histone Acetyltransferase 1 (HAT1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Histone Acetyltransferase 1 (HAT1) CLIA assay for Antigen Detection

Reference

"Nucleosomal DNA regulates the core-histone-binding subunit of the human Hat1 acetyltransferase."
Curr. Biol. 8:96-108(1998) [PubMed] [Europe PMC] [Abstract]

"Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Effects of acetylation of histone H4 at lysines 8 and 16 on activity of the Hat1 histone acetyltransferase."
J. Biol. Chem. 276:43499-43502(2001) [PubMed] [Europe PMC] [Abstract]

"Quantitative real-time RT-PCR analysis of eight novel estrogen-regulated genes in breast cancer."
Int. J. Biol. Markers 18:123-129(2003) [PubMed] [Europe PMC] [Abstract]

"Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]

"Irradiation with heavy-ion particles changes the cellular distribution of human histone acetyltransferase HAT1."
Mol. Cell. Biochem. 339:271-284(2010) [PubMed] [Europe PMC] [Abstract]

"The program for processing newly synthesized histones H3.1 and H4."
Nat. Struct. Mol. Biol. 17:1343-1351(2010) [PubMed] [Europe PMC] [Abstract]

"Initial characterization of the human central proteome."
BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

"Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features."
Mol. Cell. Proteomics 11:M111.015131-M111.015131(2012) [PubMed] [Europe PMC] [Abstract]

"Structural basis for substrate specificity and catalysis of human histone acetyltransferase 1."
Proc. Natl. Acad. Sci. U.S.A. 109:8925-8930(2012) [PubMed] [Europe PMC] [Abstract]

"The consensus coding sequences of human breast and colorectal cancers."
Science 314:268-274(2006) [PubMed] [Europe PMC] [Abstract]